NU2058

Compound • C1144297

Synonyms

NU2058 • O(6)-cyclohexylmethylguanine

Linked items?Related concepts, ordered by their global importance in the network.

Prostatic Neoplasms    CDK2 gene    RB1 gene    CDKN1B gene    TYMS gene   

Related concepts

# Concept name Type Relation Support Score
1 TYMS gene Gene Known Explain 14.48496
2 CDKN1B gene Gene Known Explain 7.42473
3 RB1 gene Gene Known Explain 4.15918
4 CDK2 gene Gene Known Explain 3.16745
5 Prostatic Neoplasms Disease Known Explain 3.12441
6 AG 337 Compound Inferred Explain 0.03922
7 dUMP metabolic process Function Inferred Explain 0.02744
8 Dihydrofolate Compound Inferred Explain 0.02694
9 geraniol Compound Inferred Explain 0.02688
10 cyclopentenone Compound Inferred Explain 0.02496
11 dTMP biosynthetic process Function Inferred Explain 0.02054
12 thymidylate synthase activity Function Inferred Explain 0.01991
13 Rectal Carcinoma Disease Inferred Explain 0.01897
14 maxacalcitol Compound Inferred Explain 0.01703
15 response to organophosphorus Function Inferred Explain 0.01690
16 Prednisone Compound Inferred Explain 0.01611
17 ZD 9331 Compound Inferred Explain 0.01551
18 deoxyribonucleoside monophosphate biosynthetic process Function Inferred Explain 0.01539
19 BL1521 Compound Inferred Explain 0.01312
20 gamboge acid Compound Inferred Explain 0.01191
21 CB 1093 Compound Inferred Explain 0.01129
22 MULTIPLE ENDOCRINE NEOPLASIA, TYPE IV Disease Inferred Explain 0.01110
23 FTI 277 Compound Inferred Explain 0.01087
24 Digestive System Neoplasms Disease Inferred Explain 0.01001
25 Neuroendocrine Tumors Disease Inferred Explain 0.00929
26 Folfox protocol Other Inferred Explain 0.00923
27 KH 1060 Compound Inferred Explain 0.00911
28 equiguard Compound Inferred Explain 0.00902
29 6-(methylamino)pyrido(3,4-d)pyrimidine Compound Inferred Explain 0.00864
30 Floxuridine Compound Inferred Explain 0.00863
31 6-Mercaptopurine Compound Inferred Explain 0.00847
32 5,10-methylenetetrahydrofolate Compound Inferred Explain 0.00837
33 ICI D1694 Compound Inferred Explain 0.00834
34 1,1-bis(3'-indolyl)-1-(4-trifluoromethylphenyl)methane Compound Inferred Explain 0.00769
35 Tongue Neoplasms Disease Inferred Explain 0.00757
36 11beta-dichloro compound Compound Inferred Explain 0.00751
37 pemetrexed Compound Inferred Explain 0.00736
38 Programmed Cell Death, Type II Function Inferred Explain 0.00727
39 Medphalan Compound Inferred Explain 0.00695
40 Oligomycins Compound Inferred Explain 0.00658
41 EB 1089 Compound Inferred Explain 0.00641
42 Thymidine Monophosphate Compound Inferred Explain 0.00585
43 Chlorambucil Compound Inferred Explain 0.00582
44 CP-654577 Compound Inferred Explain 0.00575
45 2,4-thiazolidinedione Compound Inferred Explain 0.00561
46 S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea Compound Inferred Explain 0.00552
47 Reticulosarcoma Disease Inferred Explain 0.00550
48 Deoxyuracil Nucleotides Compound Inferred Explain 0.00539
49 Calcium Phytate Compound Inferred Explain 0.00528
50 Glucocorticoids Compound Inferred Explain 0.00526
51 Lymphoma, Follicular Disease Inferred Explain 0.00513
52 CDKN1A gene Gene Inferred Explain 0.00493
53 Carboplatin Compound Inferred Explain 0.00483
54 transforming growth factor beta receptor, cytoplasmic mediator activity Function Inferred Explain 0.00459
55 ZD1839 Compound Inferred Explain 0.00458
56 CCND1 gene Gene Inferred Explain 0.00456
57 One Carbon Pool by Folate Pathway Function Inferred Explain 0.00452
58 S,S'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea Compound Inferred Explain 0.00449
59 Leucovorin Compound Inferred Explain 0.00434
60 NSC 628503 Compound Inferred Explain 0.00429
61 CCNE1 gene Gene Inferred Explain 0.00419
62 panduratin A Compound Inferred Explain 0.00413
63 N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine Compound Inferred Explain 0.00404
64 allose Compound Inferred Explain 0.00400
65 Vorinostat Compound Inferred Explain 0.00398
66 Nucleotide Biosynthesis Function Inferred Explain 0.00391
67 Camptothecin Compound Inferred Explain 0.00382
68 17-(allylamino)-17-demethoxygeldanamycin Compound Inferred Explain 0.00376
69 L 868275 Compound Inferred Explain 0.00364
70 Berberine Compound Inferred Explain 0.00348
71 2-hydroxy-9-cis-octadecenoic acid Compound Inferred Explain 0.00347
72 Malathion Compound Inferred Explain 0.00342
73 SPDYA gene Gene Inferred Explain 0.00339
74 ethylenimine quinone Compound Inferred Explain 0.00337
75 Lamivudine Compound Inferred Explain 0.00335
76 pyrimidin-2-one beta-ribofuranoside Compound Inferred Explain 0.00330
77 olomoucine Compound Inferred Explain 0.00325
78 IPR020940 Domain Inferred Explain 0.00325
79 cofactor binding Function Inferred Explain 0.00323
80 oxaliplatin Compound Inferred Explain 0.00323
81 CDK4 gene Gene Inferred Explain 0.00319
82 ircinin-1 Compound Inferred Explain 0.00319
83 N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide Compound Inferred Explain 0.00318
84 Thymidylate synthase, C-terminal Domain Inferred Explain 0.00315
85 AG 1879 Compound Inferred Explain 0.00302
86 diindolylmethane Compound Inferred Explain 0.00301
87 bicalutamide Compound Inferred Explain 0.00297
88 Cholecalciferol Compound Inferred Explain 0.00297
89 negative regulation of kinase activity Function Inferred Explain 0.00296
90 Neoplasm Recurrence, Local Disease Inferred Explain 0.00290
91 HS 1030 Compound Inferred Explain 0.00289
92 HS-1199 Compound Inferred Explain 0.00289
93 CCND2 gene Gene Inferred Explain 0.00289
94 Lovastatin Compound Inferred Explain 0.00289
95 Head and Neck Neoplasms Disease Inferred Explain 0.00287
96 benzyloxycarbonylleucyl-leucyl-leucine aldehyde Compound Inferred Explain 0.00286
97 CDK6 gene Gene Inferred Explain 0.00286
98 Tegafur Compound Inferred Explain 0.00284
99 capecitabine Compound Inferred Explain 0.00282
100 dUMP biosynthetic process Function Inferred Explain 0.00282