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ABCB1 gene

Gene • C0376622

Definition

This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport.

Synonyms

ABCB1 gene • P-gp • ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Gene • P-GLYCOPROTEIN 1 • MULTIDRUG RESISTANCE 1 • ABC20 • PGY1 • ABCB1 • GP170 • MDR1 • ATP-binding cassette, sub-family B (MDR/TAP), member 1 • ATP-BINDING CASSETTE, SUBFAMILY B, MEMBER 1 • CD243 • DOXORUBICIN RESISTANCE

Linked items?Related concepts, ordered by their global importance in the network.

Protein Binding    integral to membrane    Membrane    Cyclosporine    Benzo(a)pyrene    Tetrachlorodibenzodioxin    ATP binding    nucleotide binding    Estradiol    arsenic trioxide    Calcium Valproate    pirinixic acid    Tretinoin    Fluorouracil    hydrolase activity    Adenosine Triphosphate    decitabine    Biological Transport    Calcitriol    Transmembrane Transport   

Related concepts

# Concept name Type Relation Support Score
1 ABCG2 gene Gene Inferred Explain 0.16997
2 ABCC1 gene Gene Inferred Explain 0.13221
3 GF 120918 Compound Known Explain 0.07881
4 isosafrole Compound Known Explain 0.07723
5 SR 12813 Compound Known Explain 0.07723
6 FK 463 Compound Known Explain 0.07723
7 enkephalin-Leu, Ala(2)-melphalan methyl ester- Compound Known Explain 0.07696
8 tryptanthrine Compound Known Explain 0.07632
9 cepharanthine Compound Known Explain 0.07450
10 taxane Compound Known Explain 0.07409
11 2-pyrrolino-DOX Compound Known Explain 0.07409
12 tectochrysin Compound Known Explain 0.07409
13 6-prenylchrysin Compound Known Explain 0.07409
14 albendazole sulfoxide Compound Known Explain 0.07322
15 oxfendazole Compound Known Explain 0.07322
16 beryllium fluoride Compound Known Explain 0.07317
17 GP 47779 Compound Known Explain 0.07261
18 8-azidoadenosine 5'-triphosphate Compound Known Explain 0.07142
19 apicidin Compound Known Explain 0.07104
20 CYP3A4 gene Gene Inferred Explain 0.06953
21 ABCC2 gene Gene Inferred Explain 0.06903
22 fluoroaluminum Compound Known Explain 0.06696
23 AN 215 Compound Known Explain 0.06439
24 sulfinosine Compound Known Explain 0.06411
25 acetochlor Compound Known Explain 0.06401
26 Hygromycin B Compound Known Explain 0.06400
27 Hydroxyzine Compound Known Explain 0.06344
28 Folicur Compound Known Explain 0.06292
29 plastochromanol 8 Compound Known Explain 0.06188
30 tocotrienol, beta Compound Known Explain 0.06188
31 tocotrienol, delta Compound Known Explain 0.06188
32 desloratadine Compound Known Explain 0.06106
33 azelastine Compound Known Explain 0.06091
34 6-bromoindirubin-3'-oxime Compound Known Explain 0.06090
35 2-pyrrolino-DOX-14-O-glt-RC-121 Compound Known Explain 0.06037
36 Trimethoprim Compound Known Explain 0.06025
37 Ivermectin Compound Known Explain 0.05990
38 Phosphines Compound Known Explain 0.05975
39 ginkgolide A Compound Known Explain 0.05968
40 terameprocol Compound Known Explain 0.05960
41 miltefosine Compound Known Explain 0.05955
42 4',5'-bis(N,N-bis(carboxymethyl)aminomethyl)fluorescein acetoxymethyl ester Compound Known Explain 0.05931
43 Cetirizine Compound Known Explain 0.05895
44 tocotrienol, alpha Compound Known Explain 0.05836
45 R115777 Compound Known Explain 0.05723
46 Vinca Alkaloids Compound Known Explain 0.05722
47 Fenbendazole Compound Known Explain 0.05711
48 meloxicam Compound Known Explain 0.05675
49 KT 5720 Compound Known Explain 0.05672
50 SDZ PSC 833 Compound Known Explain 0.05546
51 Polyacetylenes Compound Known Explain 0.05477
52 PKC412 Compound Known Explain 0.05466
53 Fluanxol Compound Known Explain 0.05464
54 xenobiotic-transporting ATPase activity Function Known Explain 0.05354
55 Technetium Tc 99m Sestamibi Compound Known Explain 0.05345
56 bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate), monocalcium salt Compound Known Explain 0.05275
57 Cyclosporins Compound Known Explain 0.05196
58 intercellular canaliculus Component Known Explain 0.05195
59 hypericin Compound Known Explain 0.05146
60 metolachlor Compound Known Explain 0.05102
61 desethylamiodarone Compound Known Explain 0.05080
62 Diphenhydramine Hydrochloride Compound Known Explain 0.05048
63 Lomustine Compound Known Explain 0.04990
64 imazalil Compound Known Explain 0.04977
65 3-methylquercetin Compound Known Explain 0.04937
66 Digoxin Compound Known Explain 0.04914
67 Iodoacetates Compound Known Explain 0.04899
68 Bay w 6228 Compound Known Explain 0.04878
69 Albendazole Compound Known Explain 0.04759
70 formononetin Compound Known Explain 0.04708
71 LAPTM4B gene Gene Known Explain 0.04677
72 saquinavir mesylate Compound Known Explain 0.04656
73 benzo(k)fluoranthene Compound Known Explain 0.04411
74 ginkgolide B Compound Known Explain 0.04303
75 Chloroform Compound Known Explain 0.04273
76 Puromycin Compound Known Explain 0.04251
77 artesunate Compound Known Explain 0.04161
78 Dormicum Compound Known Explain 0.04146
79 propiconazole Compound Known Explain 0.04140
80 Pratsiol Compound Known Explain 0.04132
81 hyperforin Compound Known Explain 0.04067
82 gabapentin Compound Known Explain 0.04055
83 Acenocoumarol Compound Known Explain 0.03966
84 Sesquiterpenes Compound Known Explain 0.03950
85 AG 1343 Compound Known Explain 0.03940
86 Pravastatin Compound Known Explain 0.03843
87 Polyenes Compound Known Explain 0.03779
88 Quindan Compound Known Explain 0.03759
89 oltipraz Compound Known Explain 0.03715
90 ferric nitrilotriacetate Compound Known Explain 0.03703
91 Reserpine Compound Known Explain 0.03659
92 L 660,711 Compound Known Explain 0.03626
93 chrysene Compound Known Explain 0.03574
94 antibiotic G 418 Compound Known Explain 0.03567
95 triadimefon Compound Known Explain 0.03553
96 Itraconazole Compound Known Explain 0.03532
97 ABCB4 gene Gene Inferred Explain 0.03512
98 razoxane Compound Known Explain 0.03507
99 Triprolidine Compound Known Explain 0.03507
100 Deoxyglucose Compound Known Explain 0.03463