|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
viral inhibition of MHC class I cell surface presentation
|
Disease
|
Known
|
Explain
|
129.43757
|
|
2
|
MHC class I protein binding
|
Function
|
Known
|
Explain
|
67.28680
|
|
3
|
evasion by virus of host immune response
|
Function
|
Known
|
Explain
|
66.90812
|
|
4
|
suppression by virus of host intracellular antiviral response
|
Disease
|
Inferred
|
Explain
|
29.84422
|
|
5
|
Immunoglobulin E-set
|
Domain
|
Known
|
Explain
|
15.06403
|
|
6
|
Endoplasmic Reticulum
|
Component
|
Known
|
Explain
|
1.53953
|
|
7
|
evasion of host defenses by virus
|
Function
|
Inferred
|
Explain
|
1.28747
|
|
8
|
MHC protein binding
|
Function
|
Inferred
|
Explain
|
0.82721
|
|
9
|
Herpesvirus US7/8/9/11, glycoprotein
|
Domain
|
Inferred
|
Explain
|
0.68331
|
|
10
|
TNF-alpha receptor-II, vaccinia C22L type
|
Domain
|
Inferred
|
Explain
|
0.59772
|
|
11
|
CD8B gene
|
Gene
|
Inferred
|
Explain
|
0.49426
|
|
12
|
suppression by virus of host cytokine production
|
Disease
|
Inferred
|
Explain
|
0.45542
|
|
13
|
Zinc finger, hepatitis C virus non-structural 5a-type
|
Domain
|
Inferred
|
Explain
|
0.43255
|
|
14
|
Hepatitis C virus non-structural 5a, region 1b
|
Domain
|
Inferred
|
Explain
|
0.38898
|
|
15
|
ABCB9 gene
|
Gene
|
Inferred
|
Explain
|
0.35480
|
|
16
|
TAPBP gene
|
Gene
|
Inferred
|
Explain
|
0.34064
|
|
17
|
DERL1 gene
|
Gene
|
Inferred
|
Explain
|
0.31952
|
|
18
|
KLRK1 gene
|
Gene
|
Inferred
|
Explain
|
0.31938
|
|
19
|
negative regulation of defense response to virus
|
Function
|
Inferred
|
Explain
|
0.30424
|
|
20
|
evasion or tolerance of host immune response
|
Function
|
Inferred
|
Explain
|
0.30026
|
|
21
|
CD8A gene
|
Gene
|
Inferred
|
Explain
|
0.27245
|
|
22
|
TUBB2C gene
|
Gene
|
Inferred
|
Explain
|
0.26033
|
|
23
|
regulation of defense response to virus by virus
|
Function
|
Inferred
|
Explain
|
0.24972
|
|
24
|
TAP2 gene
|
Gene
|
Inferred
|
Explain
|
0.24216
|
|
25
|
TAP1 gene
|
Gene
|
Inferred
|
Explain
|
0.20234
|
|
26
|
ATP5A1 gene
|
Gene
|
Inferred
|
Explain
|
0.17868
|
|
27
|
ATP5B gene
|
Gene
|
Inferred
|
Explain
|
0.14916
|
|
28
|
EIF2AK2 gene
|
Gene
|
Inferred
|
Explain
|
0.10337
|
|
29
|
TUBB gene
|
Gene
|
Inferred
|
Explain
|
0.10145
|
|
30
|
integral to endoplasmic reticulum membrane
|
Component
|
Inferred
|
Explain
|
0.05546
|
|
31
|
suppression by virus of host extracellular antiviral response
|
Function
|
Inferred
|
Explain
|
0.05137
|
|
32
|
tumor necrosis factor receptor activity
|
Function
|
Inferred
|
Explain
|
0.04502
|
|
33
|
TRGV3 gene
|
Gene
|
Inferred
|
Explain
|
0.03682
|
|
34
|
TNFR/CD27/30/40/95 cysteine-rich region
|
Domain
|
Inferred
|
Explain
|
0.03553
|
|
35
|
suppression by virus of host termination of protein biosynthetic process
|
Disease
|
Inferred
|
Explain
|
0.03144
|
|
36
|
TRBV12-3 gene
|
Gene
|
Inferred
|
Explain
|
0.03131
|
|
37
|
MHC class II protein binding
|
Function
|
Inferred
|
Explain
|
0.02889
|
|
38
|
negative regulation by organism of defense response of other organism during symbiotic interaction
|
Function
|
Inferred
|
Explain
|
0.02760
|
|
39
|
TRAC gene
|
Gene
|
Inferred
|
Explain
|
0.02745
|
|
40
|
modulation by symbiont of host immune response
|
Function
|
Inferred
|
Explain
|
0.02708
|
|
41
|
evasion or tolerance of host defenses
|
Function
|
Inferred
|
Explain
|
0.02274
|
|
42
|
Immune Evasion
|
Function
|
Inferred
|
Explain
|
0.02172
|
|
43
|
evasion or tolerance by symbiont of host-produced phytoalexins
|
Function
|
Inferred
|
Explain
|
0.02067
|
|
44
|
Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit
|
Domain
|
Inferred
|
Explain
|
0.01871
|
|
45
|
evasion or tolerance by symbiont of host-produced nitric oxide
|
Function
|
Inferred
|
Explain
|
0.01805
|
|
46
|
active evasion of host immune response
|
Function
|
Inferred
|
Explain
|
0.01783
|
|
47
|
Arrestin
|
Domain
|
Inferred
|
Explain
|
0.01774
|
|
48
|
GMP phosphodiesterase, delta subunit
|
Domain
|
Inferred
|
Explain
|
0.01704
|
|
49
|
evasion or tolerance by symbiont of host-produced reactive oxygen species
|
Function
|
Inferred
|
Explain
|
0.01700
|
|
50
|
passive evasion of host immune response
|
Function
|
Inferred
|
Explain
|
0.01658
|
|
51
|
response to host immune response
|
Function
|
Inferred
|
Explain
|
0.01573
|
|
52
|
Arrestin, conserved site
|
Domain
|
Inferred
|
Explain
|
0.01572
|
|
53
|
Arrestin, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.01547
|
|
54
|
evasion or tolerance of host defense response
|
Function
|
Inferred
|
Explain
|
0.01530
|
|
55
|
Glucan biosynthesis, periplasmic, MdoG C-terminal
|
Domain
|
Inferred
|
Explain
|
0.01511
|
|
56
|
peptide antigen binding
|
Function
|
Inferred
|
Explain
|
0.01498
|
|
57
|
Glucan biosynthesis, periplasmic, MdoG
|
Domain
|
Inferred
|
Explain
|
0.01445
|
|
58
|
Glycoside hydrolase, family 13, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.01420
|
|
59
|
MD-2-related lipid-recognition
|
Domain
|
Inferred
|
Explain
|
0.01304
|
|
60
|
Endoplasmic reticulum, membrane
|
Component
|
Inferred
|
Explain
|
0.01280
|
|
61
|
Filamin/ABP280 repeat-like
|
Domain
|
Inferred
|
Explain
|
0.01260
|
|
62
|
Filamin/ABP280 repeat
|
Domain
|
Inferred
|
Explain
|
0.01219
|
|
63
|
TAP1 binding
|
Function
|
Inferred
|
Explain
|
0.01199
|
|
64
|
TAP2 binding
|
Function
|
Inferred
|
Explain
|
0.01199
|
|
65
|
Arrestin, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.01143
|
|
66
|
Cyclomaltodextrinase, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.01139
|
|
67
|
Domain of unknown function DUF1929
|
Domain
|
Inferred
|
Explain
|
0.01139
|
|
68
|
Alpha-1,6-glucosidases, pullulanase-type
|
Domain
|
Inferred
|
Explain
|
0.01126
|
|
69
|
Transglutaminase, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.01031
|
|
70
|
Copper resistance protein CopC/internalin, immunoglobulin-like
|
Domain
|
Inferred
|
Explain
|
0.01026
|
|
71
|
Immunoglobulin-like fold
|
Domain
|
Inferred
|
Explain
|
0.00988
|
|
72
|
RHO protein GDP dissociation inhibitor
|
Domain
|
Inferred
|
Explain
|
0.00986
|
|
73
|
Peptidase C25, C-terminal Ig-like region
|
Domain
|
Inferred
|
Explain
|
0.00975
|
|
74
|
Protein of unknown function DUF291
|
Domain
|
Inferred
|
Explain
|
0.00964
|
|
75
|
LY86 gene
|
Gene
|
Inferred
|
Explain
|
0.00942
|
|
76
|
Chitinase A N-terminal
|
Domain
|
Inferred
|
Explain
|
0.00924
|
|
77
|
Transcription factor COE
|
Domain
|
Inferred
|
Explain
|
0.00914
|
|
78
|
Hemocyanin, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.00903
|
|
79
|
virus-host interaction
|
Function
|
Inferred
|
Explain
|
0.00873
|
|
80
|
Malto-oligosyltrehalose trehalohydrolase
|
Domain
|
Inferred
|
Explain
|
0.00864
|
|
81
|
Glycoside hydrolase, family 20, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.00856
|
|
82
|
Cell surface receptor IPT/TIG
|
Domain
|
Inferred
|
Explain
|
0.00847
|
|
83
|
CLEC7A gene
|
Gene
|
Inferred
|
Explain
|
0.00844
|
|
84
|
oligopeptide-transporting ATPase activity
|
Function
|
Inferred
|
Explain
|
0.00826
|
|
85
|
TAP complex
|
Component
|
Inferred
|
Explain
|
0.00812
|
|
86
|
Glycoside hydrolase, family 13, N-terminal Ig-like region
|
Domain
|
Inferred
|
Explain
|
0.00808
|
|
87
|
tapasin binding
|
Function
|
Inferred
|
Explain
|
0.00801
|
|
88
|
1,4-alpha-glucan branching enzyme, core region
|
Domain
|
Inferred
|
Explain
|
0.00800
|
|
89
|
Glycoside hydrolase, family 9, N-terminal, Ig-like
|
Domain
|
Inferred
|
Explain
|
0.00798
|
|
90
|
passive evasion of immune response of other organism during symbiotic interaction
|
Function
|
Inferred
|
Explain
|
0.00794
|
|
91
|
Flaviviral glycoprotein E, immunoglobulin-like
|
Domain
|
Inferred
|
Explain
|
0.00791
|
|
92
|
TGM7 gene
|
Gene
|
Inferred
|
Explain
|
0.00778
|
|
93
|
active evasion of immune response of other organism during symbiotic interaction
|
Function
|
Inferred
|
Explain
|
0.00773
|
|
94
|
Glycogen debranching enzyme GlgX
|
Domain
|
Inferred
|
Explain
|
0.00758
|
|
95
|
PDE6D gene
|
Gene
|
Inferred
|
Explain
|
0.00754
|
|
96
|
Moybdenum cofactor oxidoreductase, dimerisation
|
Domain
|
Inferred
|
Explain
|
0.00745
|
|
97
|
TRIM3 gene
|
Gene
|
Inferred
|
Explain
|
0.00714
|
|
98
|
evasion or tolerance by organism of phytoalexins produced by other organism during symbiotic interaction
|
Function
|
Inferred
|
Explain
|
0.00678
|
|
99
|
IPR020739
|
Domain
|
Inferred
|
Explain
|
0.00672
|
|
100
|
evasion or tolerance by organism of reactive oxygen species produced by other organism during symbiotic interaction
|
Function
|
Inferred
|
Explain
|
0.00658
|