Interleukin-1

Domain • IPR000975

Synonyms

There are no synonyms of this concept in our database.

Linked items?Related concepts, ordered by their global importance in the network.

Extracellular Space    IL1B gene    IL1A gene    IL18 gene    Cytokine, IL-1-like    IL1F5 gene    IL1F7 gene    Interleukin-1, alpha/beta    IL1F8 gene    IL1F9 gene    IL1F6 gene    IPR020877    Interleukin-1 receptor antagonist IL1RA    Interleukin 18   

Related concepts

# Concept name Type Relation Support Score
1 Interleukin-1 receptor antagonist IL1RA Domain Known Explain 22.07974
2 Interleukin 18 Domain Known Explain 19.26421
3 IPR020877 Domain Known Explain 18.52127
4 Interleukin-1, alpha/beta Domain Known Explain 14.58602
5 IL1F6 gene Gene Known Explain 14.13391
6 IL1F8 gene Gene Known Explain 14.02075
7 IL1F9 gene Gene Known Explain 13.31687
8 IL1F7 gene Gene Known Explain 11.85434
9 Cytokine, IL-1-like Domain Known Explain 11.15766
10 IL1F5 gene Gene Known Explain 10.29310
11 IL18 gene Gene Known Explain 4.93751
12 IL1A gene Gene Known Explain 2.23247
13 interleukin-1 receptor binding activity Function Inferred Explain 2.15248
14 interleukin-1 receptor antagonist activity Function Inferred Explain 1.67611
15 Interleukin-1, beta IL1B Domain Inferred Explain 1.46598
16 IL1B gene Gene Known Explain 0.74501
17 Interleukin-1, alpha IL1A Domain Inferred Explain 0.69038
18 Triclosan Compound Inferred Explain 0.66559
19 Extracellular Space Other Known Explain 0.62116
20 Interleukin-1 propeptide Domain Inferred Explain 0.39445
21 cytokine activity Function Inferred Explain 0.38127
22 Lipopolysaccharides Compound Inferred Explain 0.27385
23 IL18BP gene Gene Inferred Explain 0.17058
24 Immune response Function Inferred Explain 0.16771
25 Inflammatory Response Disease Inferred Explain 0.10980
26 IL18R1 gene Gene Inferred Explain 0.08950
27 extracellular region Component Inferred Explain 0.07059
28 SSBP4 gene Gene Inferred Explain 0.05205
29 IL1F10 gene Gene Inferred Explain 0.05182
30 fibroblast growth factor receptor antagonist activity Function Inferred Explain 0.04652
31 SSBP2 gene Gene Inferred Explain 0.04546
32 CASP1 gene Gene Inferred Explain 0.04002
33 negative regulation of cytokine-mediated signaling pathway Function Inferred Explain 0.03635
34 CASP4 gene Gene Inferred Explain 0.03279
35 Intercellular Communication Function Inferred Explain 0.02575
36 vanadyl sulfate Compound Inferred Explain 0.02504
37 paricalcitol Compound Inferred Explain 0.02449
38 interleukin-1, Type II receptor binding Function Inferred Explain 0.02438
39 T-helper 1 type immune response Function Inferred Explain 0.02425
40 Cytokine Receptor Binding Function Inferred Explain 0.02140
41 ZNF512B gene Gene Inferred Explain 0.01860
42 Phosphorus Compound Inferred Explain 0.01847
43 cytokine biosynthesis Function Inferred Explain 0.01845
44 SMAD3 gene Gene Inferred Explain 0.01748
45 IL1RN gene Gene Inferred Explain 0.01720
46 receptor antagonist activity Function Inferred Explain 0.01703
47 Interleukin 1/heparin-binding growth factor Domain Inferred Explain 0.01686
48 MCM6 gene Gene Inferred Explain 0.01506
49 PXDN gene Gene Inferred Explain 0.01494
50 granulocyte macrophage colony-stimulating factor biosynthetic process Function Inferred Explain 0.01414
51 interleukin-13 biosynthetic process Function Inferred Explain 0.01414
52 interferon-gamma biosynthetic process Function Inferred Explain 0.01318
53 interleukin-2 biosynthetic process Function Inferred Explain 0.01255
54 Lipid A Compound Inferred Explain 0.01159
55 Zirconium Compound Inferred Explain 0.01116
56 T-helper 2 type immune response Function Inferred Explain 0.01115
57 positive regulation of granulocyte macrophage colony-stimulating factor production Function Inferred Explain 0.01022
58 SKIL gene Gene Inferred Explain 0.01021
59 chemokine biosynthetic process Function Inferred Explain 0.00947
60 FGF11 gene Gene Inferred Explain 0.00947
61 positive regulation of NK T cell proliferation Function Inferred Explain 0.00916
62 IL18RAP gene Gene Inferred Explain 0.00899
63 anthranilic acid Compound Inferred Explain 0.00896
64 FGF22 gene Gene Inferred Explain 0.00860
65 IL1RL2 gene Gene Inferred Explain 0.00841
66 FK 565 Compound Inferred Explain 0.00837
67 growth factor receptor binding Function Inferred Explain 0.00833
68 interleukin-18 binding activity Function Inferred Explain 0.00832
69 Caffeic Acid Phenethyl Ester Compound Inferred Explain 0.00767
70 FGF12 gene Gene Inferred Explain 0.00765
71 Picryl Chloride Compound Inferred Explain 0.00765
72 FGF16 gene Gene Inferred Explain 0.00759
73 FGF17 gene Gene Inferred Explain 0.00757
74 20-Methylcholanthrene Compound Inferred Explain 0.00730
75 positive regulation of natural killer cell proliferation Function Inferred Explain 0.00724
76 fibroblast growth factor receptor binding Function Inferred Explain 0.00719
77 IL12B gene Gene Inferred Explain 0.00701
78 Iron Chelating Agents Compound Inferred Explain 0.00700
79 positive regulation of interleukin-17 production Function Inferred Explain 0.00693
80 Cytokine-cytokine receptor interaction - Homo sapiens (human) Pathway Inferred Explain 0.00667
81 positive regulation of tissue remodeling Function Inferred Explain 0.00654
82 FGF21 gene Gene Inferred Explain 0.00649
83 Sarcoidosis Disease Inferred Explain 0.00639
84 pyridoxine Compound Inferred Explain 0.00629
85 TLR5 gene Gene Inferred Explain 0.00625
86 FGF20 gene Gene Inferred Explain 0.00623
87 aluminum sulfate Compound Inferred Explain 0.00608
88 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Compound Inferred Explain 0.00600
89 FGF19 gene Gene Inferred Explain 0.00583
90 FGF6 gene Gene Inferred Explain 0.00583
91 FGF14 gene Gene Inferred Explain 0.00576
92 positive regulation of activated T cell proliferation Function Inferred Explain 0.00574
93 FGF5 gene Gene Inferred Explain 0.00573
94 IRAK4 gene Gene Inferred Explain 0.00556
95 positive regulation of interferon-gamma production Function Inferred Explain 0.00542
96 Thiamine Compound Inferred Explain 0.00529
97 IL1RAP gene Gene Inferred Explain 0.00526
98 FGF13 gene Gene Inferred Explain 0.00517
99 FGF18 gene Gene Inferred Explain 0.00503
100 Acetylmuramyl-Alanyl-Isoglutamine Compound Inferred Explain 0.00483