|
2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid
Related concepts
|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
Pleurisy
|
Disease
|
Known
|
Explain
|
44.29737
|
|
2
|
PTGES2 gene
|
Gene
|
Known
|
Explain
|
17.11448
|
|
3
|
Inflammation
|
Disease
|
Known
|
Explain
|
5.12148
|
|
4
|
Pleuropneumonia
|
Disease
|
Inferred
|
Explain
|
4.04412
|
|
5
|
PPARA gene
|
Gene
|
Known
|
Explain
|
3.44124
|
|
6
|
Carrageenan
|
Compound
|
Inferred
|
Explain
|
3.04312
|
|
7
|
PPARG gene
|
Gene
|
Known
|
Explain
|
2.15566
|
|
8
|
IL1B gene
|
Gene
|
Known
|
Explain
|
1.69202
|
|
9
|
PTGS2 gene
|
Gene
|
Known
|
Explain
|
1.57484
|
|
10
|
Pleural Diseases
|
Disease
|
Inferred
|
Explain
|
1.24843
|
|
11
|
Respiratory Tract Infections
|
Disease
|
Inferred
|
Explain
|
0.76800
|
|
12
|
Pneumonia
|
Disease
|
Inferred
|
Explain
|
0.52895
|
|
13
|
prostaglandin-E synthase activity
|
Function
|
Inferred
|
Explain
|
0.07133
|
|
14
|
Prostaglandin H2
|
Compound
|
Inferred
|
Explain
|
0.04449
|
|
15
|
PTGFR gene
|
Gene
|
Inferred
|
Explain
|
0.03986
|
|
16
|
prostaglandin biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.03927
|
|
17
|
Edema
|
Disease
|
Inferred
|
Explain
|
0.02426
|
|
18
|
Empyema, Pleural
|
Disease
|
Inferred
|
Explain
|
0.02130
|
|
19
|
Pleural Tuberculosis
|
Disease
|
Inferred
|
Explain
|
0.02123
|
|
20
|
Lipopolysaccharides
|
Compound
|
Inferred
|
Explain
|
0.02069
|
|
21
|
Fibrosarcoma
|
Disease
|
Inferred
|
Explain
|
0.02038
|
|
22
|
protein disulfide oxidoreductase activity
|
Function
|
Inferred
|
Explain
|
0.02021
|
|
23
|
Hemothorax
|
Disease
|
Inferred
|
Explain
|
0.01990
|
|
24
|
Chylothorax
|
Disease
|
Inferred
|
Explain
|
0.01678
|
|
25
|
Hydrothorax
|
Disease
|
Inferred
|
Explain
|
0.01678
|
|
26
|
Dinoprostone
|
Compound
|
Inferred
|
Explain
|
0.01626
|
|
27
|
Hemopneumothorax
|
Disease
|
Inferred
|
Explain
|
0.01616
|
|
28
|
Chylothorax, congenital
|
Disease
|
Inferred
|
Explain
|
0.01613
|
|
29
|
Arachidonic Acid Metabolism Pathway
|
Function
|
Inferred
|
Explain
|
0.01516
|
|
30
|
EXOSC10 gene
|
Gene
|
Inferred
|
Explain
|
0.01397
|
|
31
|
Arthritis, Adjuvant-Induced
|
Disease
|
Inferred
|
Explain
|
0.01347
|
|
32
|
TZI 41127
|
Compound
|
Inferred
|
Explain
|
0.01250
|
|
33
|
Cell secretion
|
Function
|
Inferred
|
Explain
|
0.01245
|
|
34
|
cacospongionolide B
|
Compound
|
Inferred
|
Explain
|
0.01209
|
|
35
|
petrosaspongiolide m
|
Compound
|
Inferred
|
Explain
|
0.01186
|
|
36
|
aloe emodin
|
Compound
|
Inferred
|
Explain
|
0.01175
|
|
37
|
bolinaquinone
|
Compound
|
Inferred
|
Explain
|
0.01168
|
|
38
|
perfluorooctanoic acid
|
Compound
|
Inferred
|
Explain
|
0.01142
|
|
39
|
flunisolide
|
Compound
|
Inferred
|
Explain
|
0.01138
|
|
40
|
TNF gene
|
Gene
|
Inferred
|
Explain
|
0.01130
|
|
41
|
cell redox homeostasis
|
Function
|
Inferred
|
Explain
|
0.01106
|
|
42
|
Flexidol
|
Compound
|
Inferred
|
Explain
|
0.01099
|
|
43
|
2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran
|
Compound
|
Inferred
|
Explain
|
0.01068
|
|
44
|
Mecholyl
|
Compound
|
Inferred
|
Explain
|
0.01063
|
|
45
|
1-(4-(benzothiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid
|
Compound
|
Inferred
|
Explain
|
0.01030
|
|
46
|
Foreign-Body Reaction
|
Disease
|
Inferred
|
Explain
|
0.01027
|
|
47
|
MDL 28170
|
Compound
|
Inferred
|
Explain
|
0.01018
|
|
48
|
Pleural effusion disorder
|
Disease
|
Inferred
|
Explain
|
0.01000
|
|
49
|
tcdA protein, Clostridium difficile
|
Compound
|
Inferred
|
Explain
|
0.00986
|
|
50
|
ethylisopropylamiloride
|
Compound
|
Inferred
|
Explain
|
0.00984
|
|
51
|
CEBPB gene
|
Gene
|
Inferred
|
Explain
|
0.00958
|
|
52
|
Polysaccharides
|
Compound
|
Inferred
|
Explain
|
0.00943
|
|
53
|
Quartz
|
Compound
|
Inferred
|
Explain
|
0.00937
|
|
54
|
Empyema, Tuberculous
|
Disease
|
Inferred
|
Explain
|
0.00906
|
|
55
|
Bleomycin A2
|
Compound
|
Inferred
|
Explain
|
0.00884
|
|
56
|
Fenoprofen
|
Compound
|
Inferred
|
Explain
|
0.00875
|
|
57
|
Roxithromycin
|
Compound
|
Inferred
|
Explain
|
0.00871
|
|
58
|
nimesulide
|
Compound
|
Inferred
|
Explain
|
0.00867
|
|
59
|
Fibrates
|
Compound
|
Inferred
|
Explain
|
0.00856
|
|
60
|
PTGES gene
|
Gene
|
Inferred
|
Explain
|
0.00852
|
|
61
|
Systemic Inflammatory Response Syndrome
|
Disease
|
Inferred
|
Explain
|
0.00823
|
|
62
|
Freund's Adjuvant
|
Compound
|
Inferred
|
Explain
|
0.00821
|
|
63
|
fatty acid biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.00800
|
|
64
|
Plant Oils
|
Compound
|
Inferred
|
Explain
|
0.00776
|
|
65
|
honokiol
|
Compound
|
Inferred
|
Explain
|
0.00763
|
|
66
|
Metals
|
Compound
|
Inferred
|
Explain
|
0.00745
|
|
67
|
resveratrol
|
Compound
|
Inferred
|
Explain
|
0.00709
|
|
68
|
Pneumothorax
|
Disease
|
Inferred
|
Explain
|
0.00699
|
|
69
|
Zinc Sulfate
|
Compound
|
Inferred
|
Explain
|
0.00698
|
|
70
|
Pleural Neoplasms
|
Disease
|
Inferred
|
Explain
|
0.00697
|
|
71
|
ursolic acid
|
Compound
|
Inferred
|
Explain
|
0.00677
|
|
72
|
Desmodium gangeticum extract
|
Compound
|
Inferred
|
Explain
|
0.00676
|
|
73
|
pioglitazone
|
Compound
|
Inferred
|
Explain
|
0.00668
|
|
74
|
Tolmetin
|
Compound
|
Inferred
|
Explain
|
0.00667
|
|
75
|
Bupivacaine
|
Compound
|
Inferred
|
Explain
|
0.00667
|
|
76
|
Synflex
|
Compound
|
Inferred
|
Explain
|
0.00658
|
|
77
|
isomerase activity
|
Function
|
Inferred
|
Explain
|
0.00635
|
|
78
|
Respiratory Tract Diseases
|
Disease
|
Inferred
|
Explain
|
0.00628
|
|
79
|
Neurogenic Inflammation
|
Other
|
Inferred
|
Explain
|
0.00625
|
|
80
|
Diclofenac
|
Compound
|
Inferred
|
Explain
|
0.00622
|
|
81
|
L 660,711
|
Compound
|
Inferred
|
Explain
|
0.00619
|
|
82
|
Iodine
|
Compound
|
Inferred
|
Explain
|
0.00615
|
|
83
|
Suppurative inflammation
|
Disease
|
Inferred
|
Explain
|
0.00590
|
|
84
|
Analgesics, Anti-Inflammatory
|
Compound
|
Inferred
|
Explain
|
0.00576
|
|
85
|
Mangifera indica extract
|
Compound
|
Inferred
|
Explain
|
0.00566
|
|
86
|
Crotalid Venoms
|
Compound
|
Inferred
|
Explain
|
0.00562
|
|
87
|
Oleanolic Acid
|
Compound
|
Inferred
|
Explain
|
0.00554
|
|
88
|
Pleural Effusion, Malignant
|
Disease
|
Inferred
|
Explain
|
0.00547
|
|
89
|
Triclosan
|
Compound
|
Inferred
|
Explain
|
0.00539
|
|
90
|
Zinc
|
Compound
|
Inferred
|
Explain
|
0.00525
|
|
91
|
Heme
|
Compound
|
Inferred
|
Explain
|
0.00516
|
|
92
|
PTGER4 gene
|
Gene
|
Inferred
|
Explain
|
0.00513
|
|
93
|
H2AFX gene
|
Gene
|
Inferred
|
Explain
|
0.00501
|
|
94
|
Flurbiprofen
|
Compound
|
Inferred
|
Explain
|
0.00498
|
|
95
|
ONO-RS 411
|
Compound
|
Inferred
|
Explain
|
0.00495
|
|
96
|
Silver
|
Compound
|
Inferred
|
Explain
|
0.00480
|
|
97
|
LTB4R gene
|
Gene
|
Inferred
|
Explain
|
0.00476
|
|
98
|
Zymosan
|
Compound
|
Inferred
|
Explain
|
0.00476
|
|
99
|
Anafranil
|
Compound
|
Inferred
|
Explain
|
0.00473
|
|
100
|
mangiferin
|
Compound
|
Inferred
|
Explain
|
0.00473
|
|