|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
smooth muscle adaptation
|
Function
|
Known
|
Explain
|
228.12654
|
|
2
|
NOS3 gene
|
Gene
|
Known
|
Explain
|
14.20794
|
|
3
|
HMOX1 gene
|
Gene
|
Known
|
Explain
|
13.89631
|
|
4
|
smooth muscle atrophy
|
Disease
|
Inferred
|
Explain
|
5.13801
|
|
5
|
smooth muscle hypertrophy
|
Disease
|
Inferred
|
Explain
|
4.13450
|
|
6
|
muscle adaptation
|
Function
|
Inferred
|
Explain
|
3.48213
|
|
7
|
Muscular Atrophy
|
Disease
|
Inferred
|
Explain
|
0.87673
|
|
8
|
Muscle hypertrophy
|
Function
|
Inferred
|
Explain
|
0.15900
|
|
9
|
IL1B gene
|
Gene
|
Inferred
|
Explain
|
0.15640
|
|
10
|
striated muscle adaptation
|
Function
|
Inferred
|
Explain
|
0.10195
|
|
11
|
muscle hypertrophy in response to stress
|
Function
|
Inferred
|
Explain
|
0.08713
|
|
12
|
muscle system process
|
Function
|
Inferred
|
Explain
|
0.07231
|
|
13
|
striated muscle atrophy
|
Disease
|
Inferred
|
Explain
|
0.05155
|
|
14
|
Haem oxygenase
|
Domain
|
Inferred
|
Explain
|
0.04163
|
|
15
|
HMOX2 gene
|
Gene
|
Inferred
|
Explain
|
0.03951
|
|
16
|
Haem oxygenase conserved site
|
Domain
|
Inferred
|
Explain
|
0.03533
|
|
17
|
Haem oxygenase-like
|
Domain
|
Inferred
|
Explain
|
0.03473
|
|
18
|
CYBA gene
|
Gene
|
Inferred
|
Explain
|
0.02657
|
|
19
|
heme oxygenase (decyclizing) activity
|
Function
|
Inferred
|
Explain
|
0.02618
|
|
20
|
Haem oxygenase-like, multi-helical
|
Domain
|
Inferred
|
Explain
|
0.02259
|
|
21
|
heme oxidation
|
Function
|
Inferred
|
Explain
|
0.02118
|
|
22
|
cardiac muscle adaptation
|
Function
|
Inferred
|
Explain
|
0.02009
|
|
23
|
skeletal muscle adaptation
|
Function
|
Inferred
|
Explain
|
0.01741
|
|
24
|
Amyotrophy, monomelic
|
Disease
|
Inferred
|
Explain
|
0.01707
|
|
25
|
Muscular Atrophy, Spinal, Type II
|
Disease
|
Inferred
|
Explain
|
0.01498
|
|
26
|
Scapuloperoneal Form of Spinal Muscular Atrophy
|
Disease
|
Inferred
|
Explain
|
0.01477
|
|
27
|
PKC412
|
Compound
|
Inferred
|
Explain
|
0.01395
|
|
28
|
Mastocytosis, Systemic
|
Disease
|
Inferred
|
Explain
|
0.01387
|
|
29
|
Primrose syndrome
|
Disease
|
Inferred
|
Explain
|
0.01369
|
|
30
|
Juvenile Spinal Muscular Atrophy
|
Disease
|
Inferred
|
Explain
|
0.01355
|
|
31
|
HMN (Hereditary Motor Neuropathy) Proximal Type I
|
Disease
|
Inferred
|
Explain
|
0.01294
|
|
32
|
cardiac muscle atrophy
|
Disease
|
Inferred
|
Explain
|
0.01285
|
|
33
|
AMYOTROPHY, HEREDITARY NEURALGIC
|
Disease
|
Inferred
|
Explain
|
0.01268
|
|
34
|
Hemoglobin
|
Compound
|
Inferred
|
Explain
|
0.01194
|
|
35
|
Globin
|
Compound
|
Inferred
|
Explain
|
0.01194
|
|
36
|
lipopolysaccharide A
|
Compound
|
Inferred
|
Explain
|
0.01117
|
|
37
|
cobaltiprotoporphyrin
|
Compound
|
Inferred
|
Explain
|
0.01110
|
|
38
|
Atrophic
|
Disease
|
Inferred
|
Explain
|
0.01104
|
|
39
|
Spinal Muscular Atrophy
|
Disease
|
Inferred
|
Explain
|
0.01103
|
|
40
|
healing during inflammatory response
|
Function
|
Inferred
|
Explain
|
0.01071
|
|
41
|
Hyperkalemic periodic paralysis
|
Disease
|
Inferred
|
Explain
|
0.01058
|
|
42
|
MUSCULAR ATROPHY, ATAXIA, RETINITIS PIGMENTOSA, AND DIABETES MELLITUS
|
Other
|
Inferred
|
Explain
|
0.01029
|
|
43
|
tin mesoporphyrin
|
Compound
|
Inferred
|
Explain
|
0.01023
|
|
44
|
Alcoholic Silver Nitrate
|
Compound
|
Inferred
|
Explain
|
0.01022
|
|
45
|
cadmium sulfate
|
Compound
|
Inferred
|
Explain
|
0.01022
|
|
46
|
tin protoporphyrin IX
|
Compound
|
Inferred
|
Explain
|
0.01020
|
|
47
|
Allan-Herndon-Dudley syndrome (AHDS)
|
Disease
|
Inferred
|
Explain
|
0.01019
|
|
48
|
Carpal Tunnel Syndrome
|
Disease
|
Inferred
|
Explain
|
0.01009
|
|
49
|
Wieacker-Wolff syndrome
|
Disease
|
Inferred
|
Explain
|
0.00994
|
|
50
|
Biliverdine
|
Compound
|
Inferred
|
Explain
|
0.00989
|
|
51
|
cardiac muscle hypertrophy in response to stress
|
Function
|
Inferred
|
Explain
|
0.00981
|
|
52
|
octachlorostyrene
|
Compound
|
Inferred
|
Explain
|
0.00952
|
|
53
|
Fe3+
|
Compound
|
Inferred
|
Explain
|
0.00939
|
|
54
|
diacetyldichlorofluorescein
|
Compound
|
Inferred
|
Explain
|
0.00916
|
|
55
|
PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET
|
Disease
|
Inferred
|
Explain
|
0.00897
|
|
56
|
glyceryl nonivamide
|
Compound
|
Inferred
|
Explain
|
0.00896
|
|
57
|
1-aminobenzotriazole
|
Compound
|
Inferred
|
Explain
|
0.00896
|
|
58
|
eriodictyol
|
Compound
|
Inferred
|
Explain
|
0.00892
|
|
59
|
MENTAL RETARDATION, X-LINKED, WITH SHORT STATURE, SMALL TESTES, MUSCLE WASTING, AND TREMOR
|
Disease
|
Inferred
|
Explain
|
0.00889
|
|
60
|
Pentaerythritol Tetranitrate
|
Compound
|
Inferred
|
Explain
|
0.00883
|
|
61
|
Fe2+
|
Compound
|
Inferred
|
Explain
|
0.00875
|
|
62
|
Neuromuscular Manifestations
|
Disease
|
Inferred
|
Explain
|
0.00868
|
|
63
|
8-bromocyclic GMP
|
Compound
|
Inferred
|
Explain
|
0.00865
|
|
64
|
fisetin
|
Compound
|
Inferred
|
Explain
|
0.00863
|
|
65
|
zinc protoporphyrin
|
Compound
|
Inferred
|
Explain
|
0.00847
|
|
66
|
positive regulation of vasodilation
|
Function
|
Inferred
|
Explain
|
0.00842
|
|
67
|
Dihematoporphyrin Ether
|
Compound
|
Inferred
|
Explain
|
0.00838
|
|
68
|
Coronary Arteriosclerosis
|
Disease
|
Inferred
|
Explain
|
0.00826
|
|
69
|
CV 664
|
Compound
|
Inferred
|
Explain
|
0.00824
|
|
70
|
negative regulation of smooth muscle cell proliferation
|
Function
|
Inferred
|
Explain
|
0.00795
|
|
71
|
negative regulation of mast cell cytokine production
|
Function
|
Inferred
|
Explain
|
0.00786
|
|
72
|
Ticlopidine Hydrochloride
|
Compound
|
Inferred
|
Explain
|
0.00783
|
|
73
|
Dynamite
|
Other
|
Inferred
|
Explain
|
0.00775
|
|
74
|
regulation of transcription from RNA polymerase II promoter in response to oxidative stress
|
Function
|
Inferred
|
Explain
|
0.00772
|
|
75
|
Ticrynafen
|
Compound
|
Inferred
|
Explain
|
0.00766
|
|
76
|
skeletal muscle atrophy
|
Function
|
Inferred
|
Explain
|
0.00745
|
|
77
|
erythrocyte homeostasis
|
Function
|
Inferred
|
Explain
|
0.00744
|
|
78
|
AGN 194310
|
Compound
|
Inferred
|
Explain
|
0.00738
|
|
79
|
Dehydroascorbic Acid
|
Compound
|
Inferred
|
Explain
|
0.00737
|
|
80
|
striated muscle hypertrophy
|
Function
|
Inferred
|
Explain
|
0.00723
|
|
81
|
low-density lipoprotein particle clearance
|
Function
|
Inferred
|
Explain
|
0.00715
|
|
82
|
tetramethylpyrazine
|
Compound
|
Inferred
|
Explain
|
0.00712
|
|
83
|
Nitroprusside
|
Compound
|
Inferred
|
Explain
|
0.00705
|
|
84
|
Carbon Monoxide
|
Compound
|
Inferred
|
Explain
|
0.00702
|
|
85
|
NOS1 gene
|
Gene
|
Inferred
|
Explain
|
0.00684
|
|
86
|
negative regulation of mast cell degranulation
|
Function
|
Inferred
|
Explain
|
0.00681
|
|
87
|
1,5-dihydro-FAD
|
Compound
|
Inferred
|
Explain
|
0.00638
|
|
88
|
AGN 193109
|
Compound
|
Inferred
|
Explain
|
0.00625
|
|
89
|
methaneselenol
|
Compound
|
Inferred
|
Explain
|
0.00623
|
|
90
|
Sodium Nitrite
|
Compound
|
Inferred
|
Explain
|
0.00619
|
|
91
|
myricetin
|
Compound
|
Inferred
|
Explain
|
0.00612
|
|
92
|
endothelial cell proliferation
|
Function
|
Inferred
|
Explain
|
0.00611
|
|
93
|
Ro 31-8220
|
Compound
|
Inferred
|
Explain
|
0.00606
|
|
94
|
acetovanillone
|
Compound
|
Inferred
|
Explain
|
0.00606
|
|
95
|
benzo(k)fluoranthene
|
Compound
|
Inferred
|
Explain
|
0.00602
|
|
96
|
BLVRB gene
|
Gene
|
Inferred
|
Explain
|
0.00599
|
|
97
|
ferrous sulfate
|
Compound
|
Inferred
|
Explain
|
0.00598
|
|
98
|
Heme
|
Compound
|
Inferred
|
Explain
|
0.00597
|
|
99
|
Coal Tar
|
Compound
|
Inferred
|
Explain
|
0.00593
|
|
100
|
Thiopental
|
Compound
|
Inferred
|
Explain
|
0.00583
|