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membrane protein intracellular domain proteolysis Function  •  C1622575

Definition: The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. [PMID:12808018][...]

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Related concepts

# Entity Type Relation Support Relative specificity
1 membrane protein proteolysis Function Known Explain
2 APH1B gene Gene Known Explain
3 APH1A gene Gene Known Explain
4 PSENEN gene Gene Known Explain
5 NCSTN gene Gene Known Explain
6 ADAM17 gene Gene Known Explain
7 PSEN2 gene Gene Known Explain
8 NGFR gene Gene Known Explain
9 PSEN1 gene Gene Known Explain
10 membrane protein ectodomain proteolysis Function Inferred Explain
11 NFKB1 gene Gene Known Explain
12 TRAF6 gene Gene Known Explain
13 RELA gene Gene Known Explain
14 HM13 gene Gene Inferred Explain
15 Notch receptor processing Function Inferred Explain
16 proteolysis involved in cellular protein catabolic process Function Inferred Explain
17 Aph-1 Domain Inferred Explain
18 positive regulation of catalytic activity Function Inferred Explain
19 amyloid precursor protein catabolic process Function Inferred Explain
20 Notch Signaling Pathway Function Inferred Explain
21 induction of apoptosis by extracellular signals Function Inferred Explain
22 Notch signaling pathway - Homo sapiens (human) Pathway Inferred Explain
23 TMED10 gene Gene Inferred Explain
24 nerve growth factor receptor signaling pathway Function Inferred Explain
25 Protein Processing, Post-Translational Function Inferred Explain
26 Alzheimer's Disease Pathway Other Inferred Explain
27 Apoptosis Function Inferred Explain
28 Wall of Golgi cistern Component Inferred Explain
29 PMA-inducible membrane protein ectodomain proteolysis Function Inferred Explain
30 endopeptidase activity Function Inferred Explain
31 Hidradenitis suppurativa, familial Disease Inferred Explain
32 peptidase activity Function Inferred Explain
33 PLXDC2 gene Gene Inferred Explain
34 aspartic-type endopeptidase activity Function Inferred Explain
35 Transport Vesicles Component Inferred Explain
36 DNER gene Gene Inferred Explain
37 BACE1 gene Gene Inferred Explain
38 VASN gene Gene Inferred Explain
39 Isoflurane Compound Inferred Explain
40 ADAM10 gene Gene Inferred Explain
41 constitutive protein ectodomain proteolysis Function Inferred Explain
42 Protein Binding Function Inferred Explain
43 DSG2 gene Gene Inferred Explain
44 Golgi Apparatus Component Inferred Explain
45 integral to plasma membrane Component Inferred Explain
46 Cell membrane Component Inferred Explain
47 Endoplasmic Reticulum Component Inferred Explain
48 TMED2 gene Gene Inferred Explain
49 Peptidase A1, beta-site APP cleaving enzyme 2, BACE 2 Domain Inferred Explain
50 APP gene Gene Inferred Explain
51 Endoplasmic reticulum, membrane Component Inferred Explain
52 LAMP1 gene Gene Inferred Explain
53 TGOLN2 gene Gene Inferred Explain
54 NOTCH3 gene Gene Inferred Explain
55 beta-amyloid metabolic process Function Inferred Explain
56 NOTCH4 gene Gene Inferred Explain
57 NPR1 gene Gene Inferred Explain
58 GOLGA2 gene Gene Inferred Explain
59 NOTCH1 gene Gene Inferred Explain
60 BACE2 gene Gene Inferred Explain
61 bisphenol A Compound Inferred Explain
62 Neurotrophin signaling pathway - Homo sapiens (human) Pathway Inferred Explain
63 Alzheimer's Disease Disease Inferred Explain
64 brain morphogenesis Function Inferred Explain
65 positive regulation of coagulation Function Inferred Explain
66 anti-apoptosis Function Inferred Explain
67 METTL2B gene Gene Inferred Explain
68 Wall of lysosome Component Inferred Explain
69 NOTCH2 gene Gene Inferred Explain
70 Peptidase A22B, signal peptide peptidase Domain Inferred Explain
71 regulation of epidermal growth factor receptor activity Function Inferred Explain
72 Cell surface Component Inferred Explain
73 anagen Function Inferred Explain
74 ciliary rootlet Component Inferred Explain
75 KCNIP4 gene Gene Inferred Explain
76 Peptidase A22, presenilin signal peptide Domain Inferred Explain
77 DAG1 gene Gene Inferred Explain
78 response to high density lipoprotein stimulus Function Inferred Explain
79 oxaprozin Compound Inferred Explain
80 dorsal/ventral neural tube patterning Function Inferred Explain
81 hemopoietic progenitor cell differentiation Function Inferred Explain
82 positive regulation of epidermal growth factor receptor activity Function Inferred Explain
83 myeloid leukocyte differentiation Function Inferred Explain
84 negative regulation of axonogenesis Function Inferred Explain
85 wound healing, spreading of epidermal cells Function Inferred Explain
86 glyceollin Compound Inferred Explain
87 Melanosomes Component Inferred Explain
88 positive regulation of T cell chemotaxis Function Inferred Explain
89 germinal center formation Function Inferred Explain
90 ICAM5 gene Gene Inferred Explain
91 oxaliplatin Compound Inferred Explain
92 neutrophil mediated immunity Function Inferred Explain
93 positive regulation of cyclin-dependent protein kinase activity during G1/S Function Inferred Explain
94 death receptor activity Function Inferred Explain
95 DLL1 gene Gene Inferred Explain
96 dendritic shaft Component Inferred Explain
97 ALZHEIMER DISEASE 4 Disease Inferred Explain
98 DOCK3 gene Gene Inferred Explain
99 interleukin-6 receptor binding activity Function Inferred Explain
100 beta-amyloid formation Function Inferred Explain

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