Fibrates

• C1449704

Definition

Analogs of CLOFIBRIC ACID which are useful at inhibiting PPAR ALPHA for treatment of HYPERLIPIDEMIAS.

Synonyms

There are no synonyms of this concept in our database.

Linked items?Related concepts, ordered by their global importance in the network.

Fenofibrate    Bezafibrate    Clofibric Acid    Gemfibrozil    Phenyl Ethers    Clofenapate   

Related concepts

# Concept name Type Relation Support Score
1 Clofenapate Compound Known Explain 616.92680
2 Phenyl Ethers Compound Known Explain 175.81141
3 Gemfibrozil Compound Known Explain 112.15155
4 Clofibric Acid Compound Known Explain 83.87210
5 Bezafibrate Compound Known Explain 79.53201
6 Fenofibrate Compound Known Explain 50.85300
7 Biphenyl Compounds Compound Inferred Explain 24.74495
8 Anisoles Compound Inferred Explain 6.20643
9 Triclosan Compound Inferred Explain 4.27427
10 Phenetidine Compound Inferred Explain 3.18430
11 Ethers Compound Inferred Explain 2.83783
12 Guaiacol Compound Inferred Explain 2.43286
13 Pentanoic Acids Compound Inferred Explain 2.10057
14 Methyl Ethers Compound Inferred Explain 0.95393
15 Phenols Compound Inferred Explain 0.91451
16 Niclofolan Compound Inferred Explain 0.88102
17 Dianisidine Compound Inferred Explain 0.82724
18 Halogenated Diphenyl Ethers Compound Inferred Explain 0.80451
19 Dyslipidemias Disease Inferred Explain 0.78985
20 Anethole Trithione Compound Inferred Explain 0.78849
21 3,3-Dichlorobenzidine Compound Inferred Explain 0.77915
22 CYP7A1 gene Gene Inferred Explain 0.74039
23 ABCG5 gene Gene Inferred Explain 0.72730
24 ABCB4 gene Gene Inferred Explain 0.67295
25 Clofibrate Compound Inferred Explain 0.46912
26 Ethyl Ethers Compound Inferred Explain 0.43339
27 NR1I2 gene Gene Inferred Explain 0.37481
28 Benzophenones Compound Inferred Explain 0.36133
29 SREBF2 gene Gene Inferred Explain 0.28446
30 Polybrominated Biphenyls Compound Inferred Explain 0.23793
31 Benzamides Compound Inferred Explain 0.23530
32 Aminophenols Compound Inferred Explain 0.19927
33 Benzene Derivatives Compound Inferred Explain 0.15123
34 CYP2C8 gene Gene Inferred Explain 0.14841
35 Ethoglucid Compound Inferred Explain 0.12317
36 Guaifenesin Compound Inferred Explain 0.12054
37 UGT1A1 gene Gene Inferred Explain 0.11370
38 Methoxyflurane Compound Inferred Explain 0.11307
39 Thiones Compound Inferred Explain 0.11298
40 Nitrophenols Compound Inferred Explain 0.10295
41 SEMA6B gene Gene Inferred Explain 0.10080
42 Losartan Compound Inferred Explain 0.09497
43 Glyceryl Ethers Compound Inferred Explain 0.08911
44 Valerates Compound Inferred Explain 0.08801
45 CYP4A11 gene Gene Inferred Explain 0.08016
46 PPARA gene Gene Inferred Explain 0.07544
47 CPT1A gene Gene Inferred Explain 0.06969
48 Flurbiprofen Compound Inferred Explain 0.06867
49 ACSL1 Gene Gene Inferred Explain 0.06339
50 CYP3A4 gene Gene Inferred Explain 0.05844
51 Catechols Compound Inferred Explain 0.05544
52 Liver neoplasms Disease Inferred Explain 0.05284
53 UGT2B7 gene Gene Inferred Explain 0.04263
54 Endometrial Neoplasms Disease Inferred Explain 0.04201
55 Ethers, Cyclic Compound Inferred Explain 0.04160
56 UGT1A3 gene Gene Inferred Explain 0.04141
57 UGT1A10 gene Gene Inferred Explain 0.03958
58 UGT1A8 gene Gene Inferred Explain 0.03779
59 UGT1A7 gene Gene Inferred Explain 0.03753
60 PCK2 gene Gene Inferred Explain 0.03629
61 MAT2A gene Gene Inferred Explain 0.03604
62 Coronary Thrombosis Disease Inferred Explain 0.03117
63 Flurothyl Compound Inferred Explain 0.03100
64 APOE gene Gene Inferred Explain 0.02621
65 Methemoglobinemia Disease Inferred Explain 0.02497
66 CYP2A6 gene Gene Inferred Explain 0.02477
67 SCARB1 gene Gene Inferred Explain 0.02442
68 CYP2C9 gene Gene Inferred Explain 0.02189
69 Valproic Acid Compound Inferred Explain 0.02007
70 CYP19A1 gene Gene Inferred Explain 0.01973
71 FAS gene Gene Inferred Explain 0.01931
72 Chlorthalidone Compound Inferred Explain 0.01898
73 Mammary Neoplasms, Experimental Disease Inferred Explain 0.01771
74 Benzhydryl Compounds Compound Inferred Explain 0.01728
75 Isoflurane Compound Inferred Explain 0.01648
76 CYP1A1 gene Gene Inferred Explain 0.01614
77 Organic Chemicals Compound Inferred Explain 0.01499
78 CRP gene Gene Inferred Explain 0.01484
79 Phloroglucinol Compound Inferred Explain 0.01406
80 Resorcinols Compound Inferred Explain 0.01344
81 Methocarbamol Compound Inferred Explain 0.01253
82 PON1 gene Gene Inferred Explain 0.01200
83 Bromphenol Blue Compound Inferred Explain 0.01005
84 Bisphenol A-Glycidyl Methacrylate Compound Inferred Explain 0.00979
85 Polychlorinated Biphenyls Compound Inferred Explain 0.00958
86 Phenolphthaleins Compound Inferred Explain 0.00953
87 Dienestrol Compound Inferred Explain 0.00920
88 Liver Cirrhosis, Experimental Disease Inferred Explain 0.00896
89 CCL2 gene Gene Inferred Explain 0.00840
90 Hippurates Compound Inferred Explain 0.00815
91 Hydrocarbons, Brominated Compound Inferred Explain 0.00764
92 Humic Substances Compound Inferred Explain 0.00748
93 Pyrogallol Compound Inferred Explain 0.00735
94 Aminohippuric Acids Compound Inferred Explain 0.00714
95 Iodohippuric Acid Compound Inferred Explain 0.00714
96 PSEN1 gene Gene Inferred Explain 0.00708
97 CA1 gene Gene Inferred Explain 0.00693
98 Niemann-Pick Disease, Type C Disease Inferred Explain 0.00691
99 2-Hydroxy-5-nitrobenzyl Bromide Compound Inferred Explain 0.00690
100 Chlorophenols Compound Inferred Explain 0.00689