|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
L-iduronidase activity
|
Function
|
Known
|
Explain
|
6.49221
|
|
2
|
Mucopolysaccharidosis I
|
Disease
|
Known
|
Explain
|
6.14635
|
|
3
|
Glycoside hydrolase, family 39
|
Domain
|
Known
|
Explain
|
5.39499
|
|
4
|
Glycosaminoglycans
|
Compound
|
Known
|
Explain
|
4.57081
|
|
5
|
disaccharide metabolic process
|
Function
|
Known
|
Explain
|
2.55904
|
|
6
|
chemical homeostasis
|
Function
|
Known
|
Explain
|
2.25097
|
|
7
|
skeletal system morphogenesis
|
Function
|
Known
|
Explain
|
2.13322
|
|
8
|
limb morphogenesis
|
Function
|
Known
|
Explain
|
2.04785
|
|
9
|
lysosome organization
|
Function
|
Known
|
Explain
|
1.92914
|
|
10
|
Glycosaminoglycan Degradation Pathway
|
Other
|
Known
|
Explain
|
1.89103
|
|
11
|
MPP3 gene
|
Gene
|
Known
|
Explain
|
1.83421
|
|
12
|
Genticin
|
Compound
|
Known
|
Explain
|
1.36341
|
|
13
|
Glycoside hydrolase, subgroup, catalytic core
|
Domain
|
Known
|
Explain
|
1.30745
|
|
14
|
cation binding
|
Function
|
Known
|
Explain
|
1.14518
|
|
15
|
cell morphogenesis
|
Function
|
Known
|
Explain
|
1.07148
|
|
16
|
Mucopolysaccharidoses
|
Disease
|
Inferred
|
Explain
|
1.05938
|
|
17
|
Glycoside hydrolase, catalytic core
|
Domain
|
Known
|
Explain
|
1.04122
|
|
18
|
Lysosome - Homo sapiens (human)
|
Pathway
|
Known
|
Explain
|
0.50653
|
|
19
|
hydrolase activity, hydrolyzing O-glycosyl compounds
|
Function
|
Inferred
|
Explain
|
0.38267
|
|
20
|
Lysosomes
|
Component
|
Known
|
Explain
|
0.37494
|
|
21
|
Carbohydrate Metabolism
|
Function
|
Known
|
Explain
|
0.29535
|
|
22
|
Chondroitin
|
Compound
|
Inferred
|
Explain
|
0.24311
|
|
23
|
Keratan Sulfate
|
Compound
|
Inferred
|
Explain
|
0.20172
|
|
24
|
melibiose metabolic process
|
Function
|
Inferred
|
Explain
|
0.19473
|
|
25
|
disaccharide catabolic process
|
Function
|
Inferred
|
Explain
|
0.15839
|
|
26
|
maltose metabolic process
|
Function
|
Inferred
|
Explain
|
0.15065
|
|
27
|
disaccharide biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.13564
|
|
28
|
Heparitin Sulfate
|
Compound
|
Inferred
|
Explain
|
0.12520
|
|
29
|
lactose metabolic process
|
Function
|
Inferred
|
Explain
|
0.10864
|
|
30
|
Water
|
Compound
|
Known
|
Explain
|
0.09715
|
|
31
|
Heparin
|
Compound
|
Inferred
|
Explain
|
0.08402
|
|
32
|
Hyaluronic Acid
|
Compound
|
Inferred
|
Explain
|
0.07939
|
|
33
|
sucrose metabolic process
|
Function
|
Inferred
|
Explain
|
0.06780
|
|
34
|
mycothiol metabolic process
|
Function
|
Inferred
|
Explain
|
0.06351
|
|
35
|
Selenite
|
Compound
|
Known
|
Explain
|
0.06305
|
|
36
|
melibiose catabolic process
|
Function
|
Inferred
|
Explain
|
0.05767
|
|
37
|
Vitamin E
|
Compound
|
Known
|
Explain
|
0.05753
|
|
38
|
Selenium
|
Compound
|
Known
|
Explain
|
0.05722
|
|
39
|
trehalose metabolic process
|
Function
|
Inferred
|
Explain
|
0.05589
|
|
40
|
melibiose biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.05244
|
|
41
|
Polysaccharides
|
Compound
|
Inferred
|
Explain
|
0.04705
|
|
42
|
maltose catabolic process
|
Function
|
Inferred
|
Explain
|
0.04282
|
|
43
|
maltose biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.03836
|
|
44
|
lactose biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.03682
|
|
45
|
imaginal disc-derived limb morphogenesis
|
Function
|
Inferred
|
Explain
|
0.03621
|
|
46
|
leg morphogenesis
|
Function
|
Inferred
|
Explain
|
0.03607
|
|
47
|
lactose catabolic process
|
Function
|
Inferred
|
Explain
|
0.03504
|
|
48
|
post-embryonic limb morphogenesis
|
Function
|
Inferred
|
Explain
|
0.03049
|
|
49
|
Cyclosporine
|
Compound
|
Known
|
Explain
|
0.02870
|
|
50
|
Chondroitin Sulfates
|
Compound
|
Inferred
|
Explain
|
0.02684
|
|
51
|
oligosaccharide metabolic process
|
Function
|
Inferred
|
Explain
|
0.02619
|
|
52
|
ARSB gene
|
Gene
|
Inferred
|
Explain
|
0.02593
|
|
53
|
hindlimb morphogenesis
|
Function
|
Inferred
|
Explain
|
0.02575
|
|
54
|
Dermatan Sulfate
|
Compound
|
Inferred
|
Explain
|
0.02547
|
|
55
|
HEXA gene
|
Gene
|
Inferred
|
Explain
|
0.02471
|
|
56
|
Glycoside hydrolase, family 30
|
Domain
|
Inferred
|
Explain
|
0.02416
|
|
57
|
EVX2 gene
|
Gene
|
Inferred
|
Explain
|
0.02360
|
|
58
|
appendage morphogenesis
|
Function
|
Inferred
|
Explain
|
0.02289
|
|
59
|
HEXB gene
|
Gene
|
Inferred
|
Explain
|
0.02215
|
|
60
|
GAA gene
|
Gene
|
Inferred
|
Explain
|
0.02163
|
|
61
|
forelimb morphogenesis
|
Function
|
Inferred
|
Explain
|
0.01934
|
|
62
|
cellular carbohydrate metabolic process
|
Function
|
Inferred
|
Explain
|
0.01891
|
|
63
|
HPSE2 gene
|
Gene
|
Inferred
|
Explain
|
0.01810
|
|
64
|
carbohydrate homeostasis
|
Function
|
Inferred
|
Explain
|
0.01731
|
|
65
|
Mucopolysaccharidosis VI
|
Disease
|
Inferred
|
Explain
|
0.01553
|
|
66
|
gas homeostasis
|
Function
|
Inferred
|
Explain
|
0.01532
|
|
67
|
polyamine homeostasis
|
Function
|
Inferred
|
Explain
|
0.01476
|
|
68
|
regulation of viral protein levels in host cell
|
Function
|
Inferred
|
Explain
|
0.01469
|
|
69
|
HPSE gene
|
Gene
|
Inferred
|
Explain
|
0.01466
|
|
70
|
Mucopolysaccharidosis III
|
Disease
|
Inferred
|
Explain
|
0.01453
|
|
71
|
Mucopolysaccharidosis IV
|
Disease
|
Inferred
|
Explain
|
0.01443
|
|
72
|
FLVCR1 gene
|
Gene
|
Inferred
|
Explain
|
0.01413
|
|
73
|
Mucopolysaccharidosis VII
|
Disease
|
Inferred
|
Explain
|
0.01412
|
|
74
|
TPP1 gene
|
Gene
|
Inferred
|
Explain
|
0.01395
|
|
75
|
Mucopolysaccharidosis II
|
Disease
|
Inferred
|
Explain
|
0.01362
|
|
76
|
Glycoside hydrolase, family 1, active site
|
Domain
|
Inferred
|
Explain
|
0.01347
|
|
77
|
GLB1L gene
|
Gene
|
Inferred
|
Explain
|
0.01263
|
|
78
|
LCTL gene
|
Gene
|
Inferred
|
Explain
|
0.01258
|
|
79
|
KBTBD4 gene
|
Gene
|
Inferred
|
Explain
|
0.01246
|
|
80
|
chemical homeostasis within a tissue
|
Function
|
Inferred
|
Explain
|
0.01238
|
|
81
|
CCDC137 gene
|
Gene
|
Inferred
|
Explain
|
0.01233
|
|
82
|
MORN2 gene
|
Gene
|
Inferred
|
Explain
|
0.01228
|
|
83
|
sucrose catabolic process
|
Function
|
Inferred
|
Explain
|
0.01218
|
|
84
|
Sucrose phosphorylase
|
Domain
|
Inferred
|
Explain
|
0.01215
|
|
85
|
MANBA gene
|
Gene
|
Inferred
|
Explain
|
0.01195
|
|
86
|
cellular chemical homeostasis
|
Function
|
Inferred
|
Explain
|
0.01191
|
|
87
|
trehalose catabolic process
|
Function
|
Inferred
|
Explain
|
0.01127
|
|
88
|
vacuole organization
|
Function
|
Inferred
|
Explain
|
0.01126
|
|
89
|
HPS1 gene
|
Gene
|
Inferred
|
Explain
|
0.01120
|
|
90
|
GALNS gene
|
Gene
|
Inferred
|
Explain
|
0.01095
|
|
91
|
water homeostasis
|
Function
|
Inferred
|
Explain
|
0.01086
|
|
92
|
B3GNTL1 gene
|
Gene
|
Inferred
|
Explain
|
0.01072
|
|
93
|
GUSB gene
|
Gene
|
Inferred
|
Explain
|
0.01070
|
|
94
|
Glycoside hydrolase family 13
|
Domain
|
Inferred
|
Explain
|
0.01049
|
|
95
|
GALC gene
|
Gene
|
Inferred
|
Explain
|
0.01048
|
|
96
|
NAGPA gene
|
Gene
|
Inferred
|
Explain
|
0.01043
|
|
97
|
embryonic limb morphogenesis
|
Function
|
Inferred
|
Explain
|
0.01025
|
|
98
|
Glycosyl hydrolase, family 13, catalytic region
|
Domain
|
Inferred
|
Explain
|
0.01008
|
|
99
|
CHID1 gene
|
Gene
|
Inferred
|
Explain
|
0.01002
|
|
100
|
Glycoside hydrolase, family 5, conserved site
|
Domain
|
Inferred
|
Explain
|
0.00999
|