|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
APOBEC3G gene
|
Gene
|
Known
|
Explain
|
17.00034
|
|
2
|
negative regulation of retroviral genome replication
|
Function
|
Known
|
Explain
|
12.33066
|
|
3
|
apolipoprotein B mRNA editing enzyme complex
|
Component
|
Known
|
Explain
|
10.77836
|
|
4
|
cytidine deamination
|
Function
|
Known
|
Explain
|
9.89003
|
|
5
|
base conversion or substitution editing
|
Function
|
Known
|
Explain
|
9.75030
|
|
6
|
negative regulation of viral reproduction
|
Function
|
Known
|
Explain
|
8.79045
|
|
7
|
positive regulation of defense response to virus by host
|
Function
|
Known
|
Explain
|
7.59037
|
|
8
|
cytidine deaminase activity
|
Function
|
Known
|
Explain
|
6.87118
|
|
9
|
Reverse Transcription
|
Function
|
Known
|
Explain
|
6.14695
|
|
10
|
negative regulation of viral genome replication
|
Function
|
Inferred
|
Explain
|
1.49820
|
|
11
|
regulation of retroviral genome replication
|
Function
|
Inferred
|
Explain
|
1.27258
|
|
12
|
APOBEC2 gene
|
Gene
|
Inferred
|
Explain
|
0.92413
|
|
13
|
Azacitidine
|
Compound
|
Known
|
Explain
|
0.86173
|
|
14
|
APOBEC1 gene
|
Gene
|
Inferred
|
Explain
|
0.74103
|
|
15
|
cytidine to uridine editing
|
Function
|
Inferred
|
Explain
|
0.59431
|
|
16
|
Innate Immune Response
|
Disease
|
Known
|
Explain
|
0.57649
|
|
17
|
A1CF gene
|
Gene
|
Inferred
|
Explain
|
0.54414
|
|
18
|
adenosine to inosine editing
|
Function
|
Inferred
|
Explain
|
0.54226
|
|
19
|
cytidine catabolic process
|
Function
|
Inferred
|
Explain
|
0.46246
|
|
20
|
AICDA gene
|
Gene
|
Inferred
|
Explain
|
0.34655
|
|
21
|
ADARB1 gene
|
Gene
|
Inferred
|
Explain
|
0.30288
|
|
22
|
CDA gene
|
Gene
|
Inferred
|
Explain
|
0.28187
|
|
23
|
ADAR gene
|
Gene
|
Inferred
|
Explain
|
0.25664
|
|
24
|
IPR020797
|
Domain
|
Inferred
|
Explain
|
0.23069
|
|
25
|
Cytidine deaminase, homodimeric
|
Domain
|
Inferred
|
Explain
|
0.23053
|
|
26
|
Cytidine/deoxycytidylate deaminase, zinc-binding region
|
Domain
|
Inferred
|
Explain
|
0.21669
|
|
27
|
RNA Binding
|
Function
|
Known
|
Explain
|
0.20749
|
|
28
|
Cytidine deaminase, homotetrameric
|
Domain
|
Inferred
|
Explain
|
0.20594
|
|
29
|
cytidine metabolic process
|
Function
|
Inferred
|
Explain
|
0.17539
|
|
30
|
decitabine
|
Compound
|
Known
|
Explain
|
0.17182
|
|
31
|
hydrolase activity
|
Function
|
Known
|
Explain
|
0.16155
|
|
32
|
RNA modification
|
Function
|
Inferred
|
Explain
|
0.13141
|
|
33
|
Selenite
|
Compound
|
Known
|
Explain
|
0.12539
|
|
34
|
negative regulation of virion penetration into host cell
|
Function
|
Inferred
|
Explain
|
0.12319
|
|
35
|
regulation of viral genome replication
|
Function
|
Inferred
|
Explain
|
0.12146
|
|
36
|
zinc ion binding
|
Function
|
Known
|
Explain
|
0.09987
|
|
37
|
regulation of viral reproduction
|
Function
|
Inferred
|
Explain
|
0.07905
|
|
38
|
Metal Ion Binding
|
Function
|
Known
|
Explain
|
0.07449
|
|
39
|
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
|
Function
|
Inferred
|
Explain
|
0.07094
|
|
40
|
pyrimidine ribonucleoside catabolic process
|
Function
|
Inferred
|
Explain
|
0.06737
|
|
41
|
deaminase activity
|
Function
|
Inferred
|
Explain
|
0.06497
|
|
42
|
Cytidine deaminase-like
|
Domain
|
Inferred
|
Explain
|
0.05913
|
|
43
|
nuclear part
|
Component
|
Inferred
|
Explain
|
0.05244
|
|
44
|
mRNA modification
|
Function
|
Inferred
|
Explain
|
0.04643
|
|
45
|
Luteovirus RNA polymerase P1-P2/replicase
|
Domain
|
Inferred
|
Explain
|
0.04250
|
|
46
|
Tombusvirus p33
|
Domain
|
Inferred
|
Explain
|
0.04250
|
|
47
|
CMP/dCMP deaminase, zinc-binding
|
Domain
|
Inferred
|
Explain
|
0.04138
|
|
48
|
Viral polyprotein, Caliciviridae N-terminal
|
Domain
|
Inferred
|
Explain
|
0.03477
|
|
49
|
Polyprotein, Potyviridae
|
Domain
|
Inferred
|
Explain
|
0.03475
|
|
50
|
positive regulation of retroviral genome replication
|
Function
|
Inferred
|
Explain
|
0.03422
|
|
51
|
Peptidase C31, arterivirus porcine ORF1A
|
Domain
|
Inferred
|
Explain
|
0.03165
|
|
52
|
Peptidase C32, arteritis virus equine ORF1A
|
Domain
|
Inferred
|
Explain
|
0.03165
|
|
53
|
IFNB1 gene
|
Gene
|
Inferred
|
Explain
|
0.02963
|
|
54
|
Picornavirus 2B protein
|
Domain
|
Inferred
|
Explain
|
0.02658
|
|
55
|
dCTP deaminase activity
|
Function
|
Inferred
|
Explain
|
0.02526
|
|
56
|
RNA-directed RNA polymerase activity
|
Function
|
Inferred
|
Explain
|
0.02258
|
|
57
|
regulation of defense response to virus by host
|
Function
|
Inferred
|
Explain
|
0.02202
|
|
58
|
TNIP1 gene
|
Gene
|
Inferred
|
Explain
|
0.02193
|
|
59
|
negative regulation of biological process
|
Function
|
Inferred
|
Explain
|
0.02191
|
|
60
|
RNA-directed RNA polymerase catalytic
|
Domain
|
Inferred
|
Explain
|
0.02087
|
|
61
|
regulation of virion penetration into host cell
|
Function
|
Inferred
|
Explain
|
0.01927
|
|
62
|
IFIT1 gene
|
Gene
|
Inferred
|
Explain
|
0.01736
|
|
63
|
APOBEC/CMP deaminase, zinc-binding
|
Domain
|
Inferred
|
Explain
|
0.01589
|
|
64
|
TMEM173 gene
|
Gene
|
Inferred
|
Explain
|
0.01302
|
|
65
|
protein complex location
|
Component
|
Inferred
|
Explain
|
0.01098
|
|
66
|
MAVS gene
|
Gene
|
Inferred
|
Explain
|
0.01092
|
|
67
|
DDX58 gene
|
Gene
|
Inferred
|
Explain
|
0.01020
|
|
68
|
IL12RB1 gene
|
Gene
|
Inferred
|
Explain
|
0.00883
|
|
69
|
positive regulation of viral genome replication
|
Function
|
Inferred
|
Explain
|
0.00869
|
|
70
|
cytidine biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.00738
|
|
71
|
IL23R gene
|
Gene
|
Inferred
|
Explain
|
0.00721
|
|
72
|
PROX1 gene
|
Gene
|
Inferred
|
Explain
|
0.00650
|
|
73
|
IL23A gene
|
Gene
|
Inferred
|
Explain
|
0.00635
|
|
74
|
mRNA processing
|
Function
|
Inferred
|
Explain
|
0.00603
|
|
75
|
pyrimidine ribonucleoside metabolic process
|
Function
|
Inferred
|
Explain
|
0.00556
|
|
76
|
RNA-protein covalent cross-linking
|
Function
|
Inferred
|
Explain
|
0.00519
|
|
77
|
pseudouridine synthesis
|
Function
|
Inferred
|
Explain
|
0.00490
|
|
78
|
Cell Nucleus
|
Component
|
Inferred
|
Explain
|
0.00489
|
|
79
|
CCL5 gene
|
Gene
|
Inferred
|
Explain
|
0.00442
|
|
80
|
PML gene
|
Gene
|
Inferred
|
Explain
|
0.00385
|
|
81
|
APOBEC-like, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.00384
|
|
82
|
Antiviral Response
|
Function
|
Inferred
|
Explain
|
0.00355
|
|
83
|
Protein Binding
|
Function
|
Inferred
|
Explain
|
0.00334
|
|
84
|
Pseudouridine synthase, catalytic domain
|
Domain
|
Inferred
|
Explain
|
0.00316
|
|
85
|
Transcription, Genetic
|
Function
|
Inferred
|
Explain
|
0.00310
|
|
86
|
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
|
Function
|
Inferred
|
Explain
|
0.00309
|
|
87
|
Cytoplasm
|
Component
|
Inferred
|
Explain
|
0.00306
|
|
88
|
PTN gene
|
Gene
|
Inferred
|
Explain
|
0.00298
|
|
89
|
Deoxycytidine triphosphate deaminase
|
Domain
|
Inferred
|
Explain
|
0.00295
|
|
90
|
DCTD gene
|
Gene
|
Inferred
|
Explain
|
0.00286
|
|
91
|
IL12B gene
|
Gene
|
Inferred
|
Explain
|
0.00283
|
|
92
|
CEBPB gene
|
Gene
|
Inferred
|
Explain
|
0.00279
|
|
93
|
dCMP deaminase
|
Domain
|
Inferred
|
Explain
|
0.00278
|
|
94
|
cytosine deaminase activity
|
Function
|
Inferred
|
Explain
|
0.00263
|
|
95
|
Pseudouridine synthase, RsuA and RluB/C/D/E/F
|
Domain
|
Inferred
|
Explain
|
0.00260
|
|
96
|
APOBEC-like, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.00256
|
|
97
|
Isoflavones
|
Compound
|
Inferred
|
Explain
|
0.00248
|
|
98
|
pseudouridine synthase activity
|
Function
|
Inferred
|
Explain
|
0.00235
|
|
99
|
Protoplasm
|
Component
|
Inferred
|
Explain
|
0.00234
|
|
100
|
Pseudouridine synthase I, TruA, alpha/beta domain
|
Domain
|
Inferred
|
Explain
|
0.00233
|