TXNIP gene

Gene • C1424661

Synonyms

TXNIP gene • THIOREDOXIN-BINDING PROTEIN 2 • thioredoxin binding protein 2 • VDUP1 • THIOREDOXIN-INTERACTING PROTEIN • thioredoxin interacting protein • EST01027 • HHCPA78 • THIF • VITAMIN D3-UPREGULATED PROTEIN 1 • TXNIP • upregulated by 1,25-dihydroxyvitamin D-3

Linked items?Related concepts, ordered by their global importance in the network.

Cell Nucleus    Protein Binding    Cytoplasm    Cyclosporine    Benzo(a)pyrene    Tetrachlorodibenzodioxin    Estradiol    arsenic trioxide    Aflatoxin B1    Fluorouracil    tert-Butylhydroperoxide    Transcriptional Regulation    decitabine    Progesterone    Calcitriol    resveratrol    Cell Cycle    testosterone enanthate    HDAC1 gene    Indomethacin   

Related concepts

# Concept name Type Relation Support Score
1 Arrestin-like, C-terminal Domain Known Explain 0.97581
2 Arrestin-like, N-terminal Domain Known Explain 0.83782
3 allose Compound Known Explain 0.77539
4 SCEL gene Gene Known Explain 0.52255
5 platelet-derived growth factor receptor signaling pathway Function Known Explain 0.40531
6 1,25-dihydroxyvitamin D Compound Known Explain 0.40381
7 Diabetic Nephropathy Disease Known Explain 0.33106
8 ZBTB32 gene Gene Known Explain 0.32987
9 response to progesterone stimulus Function Known Explain 0.28351
10 keratinocyte differentiation Function Known Explain 0.22297
11 protein import into nucleus Function Known Explain 0.22189
12 Intermembranous space of mitochondrion Component Known Explain 0.20431
13 response to hydrogen peroxide Function Known Explain 0.18844
14 arsenic disulfide Compound Known Explain 0.16736
15 response to calcium ion Function Known Explain 0.15816
16 response to mechanical stimulus Function Known Explain 0.15623
17 gedunin Compound Known Explain 0.14117
18 enzyme inhibitor activity Function Known Explain 0.13910
19 response to glucose stimulus Function Known Explain 0.13878
20 tripterine Compound Known Explain 0.13193
21 AM 251 Compound Known Explain 0.12676
22 Paraquat Compound Known Explain 0.12580
23 o,p'-DDT Compound Known Explain 0.12277
24 TXN gene Gene Known Explain 0.12259
25 Immunoglobulin E-set Domain Known Explain 0.12153
26 ubiquitin protein ligase binding Function Known Explain 0.12002
27 response to estradiol stimulus Function Known Explain 0.11867
28 KPNA2 gene Gene Known Explain 0.10915
29 TXNRD1 gene Gene Known Explain 0.10482
30 Vorinostat Compound Known Explain 0.09593
31 ZBTB16 gene Gene Known Explain 0.07868
32 Cell Proliferation Regulation Function Known Explain 0.07815
33 Arrestin, C-terminal Domain Inferred Explain 0.07813
34 SMURF2 gene Gene Known Explain 0.07767
35 response to oxidative stress Function Known Explain 0.06907
36 positive regulation of apoptosis Function Known Explain 0.06200
37 Arrestin, conserved site Domain Inferred Explain 0.05665
38 Arrestin, N-terminal Domain Inferred Explain 0.05638
39 Folic Acid Compound Known Explain 0.04888
40 Topotecan Compound Known Explain 0.04860
41 negative regulation of transcription from RNA polymerase II promoter Function Known Explain 0.04735
42 drug response Function Known Explain 0.04002
43 HDAC1 gene Gene Known Explain 0.03463
44 resveratrol Compound Known Explain 0.02787
45 Indomethacin Compound Known Explain 0.02641
46 ARRB1 gene Gene Inferred Explain 0.02468
47 testosterone enanthate Compound Known Explain 0.02426
48 Cell Cycle Function Known Explain 0.02263
49 Calcitriol Compound Known Explain 0.02124
50 ARRB2 gene Gene Inferred Explain 0.01948
51 Progesterone Compound Known Explain 0.01736
52 decitabine Compound Known Explain 0.01735
53 tert-Butylhydroperoxide Compound Known Explain 0.01620
54 Fluorouracil Compound Known Explain 0.01569
55 Estradiol Compound Known Explain 0.01444
56 Transcriptional Regulation Function Known Explain 0.01443
57 arsenic trioxide Compound Known Explain 0.01324
58 Aflatoxin B1 Compound Known Explain 0.01230
59 Tetrachlorodibenzodioxin Compound Known Explain 0.01149
60 Protein Binding Function Known Explain 0.01148
61 Benzo(a)pyrene Compound Known Explain 0.01088
62 Cell Nucleus Component Known Explain 0.01060
63 Cytoplasm Component Known Explain 0.01023
64 Cyclosporine Compound Known Explain 0.01014
65 Arrestin Domain Inferred Explain 0.00893
66 cornified envelope Component Inferred Explain 0.00772
67 CCNE1 gene Gene Inferred Explain 0.00459
68 CCNA2 gene Gene Inferred Explain 0.00439
69 CDKN1B gene Gene Inferred Explain 0.00400
70 ARID5B gene Gene Inferred Explain 0.00358
71 CCND1 gene Gene Inferred Explain 0.00321
72 TP53 gene Gene Inferred Explain 0.00303
73 Perindopril Compound Inferred Explain 0.00269
74 CSRNP1 gene Gene Inferred Explain 0.00260
75 epidermis development Function Inferred Explain 0.00258
76 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Compound Inferred Explain 0.00254
77 Esthesia Function Inferred Explain 0.00239
78 Involucrin Domain Inferred Explain 0.00234
79 Involucrin 2 Domain Inferred Explain 0.00220
80 Metal Ion Binding Function Inferred Explain 0.00204
81 VEGFA gene Gene Inferred Explain 0.00186
82 PDGFC gene Gene Inferred Explain 0.00183
83 LY96 gene Gene Inferred Explain 0.00178
84 Tretinoin Compound Inferred Explain 0.00173
85 ZFAND5 gene Gene Inferred Explain 0.00170
86 Complications of Diabetes Mellitus Disease Inferred Explain 0.00169
87 zinc ion binding Function Inferred Explain 0.00159
88 Zinc finger, LIM-type Domain Inferred Explain 0.00157
89 TIPARP gene Gene Inferred Explain 0.00154
90 Signal Transduction Function Inferred Explain 0.00152
91 Streptozocin Compound Inferred Explain 0.00150
92 SFN gene Gene Inferred Explain 0.00149
93 Cell membrane Component Inferred Explain 0.00146
94 Cytoplasmic matrix Component Inferred Explain 0.00146
95 snRNP protein import into nucleus Function Inferred Explain 0.00144
96 Membrane Component Inferred Explain 0.00143
97 MAPK1 gene Gene Inferred Explain 0.00141
98 NLS-bearing substrate import into nucleus Function Inferred Explain 0.00139
99 PLEKHA1 gene Gene Inferred Explain 0.00138
100 MAPK3 gene Gene Inferred Explain 0.00136