|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
Mesna
|
Compound
|
Known
|
Explain
|
2.57321
|
|
2
|
phosphate ion homeostasis
|
Function
|
Known
|
Explain
|
2.24825
|
|
3
|
Hypophosphatemia
|
Disease
|
Known
|
Explain
|
1.93593
|
|
4
|
sodium-dependent phosphate transmembrane transporter activity
|
Function
|
Known
|
Explain
|
1.90918
|
|
5
|
response to magnesium ion
|
Function
|
Known
|
Explain
|
1.74192
|
|
6
|
Fanconi Syndrome
|
Disease
|
Known
|
Explain
|
1.68677
|
|
7
|
HPCAL1 gene
|
Gene
|
Known
|
Explain
|
1.66906
|
|
8
|
response to lead ion
|
Function
|
Known
|
Explain
|
1.62186
|
|
9
|
BSPRY gene
|
Gene
|
Known
|
Explain
|
1.54744
|
|
10
|
YIF1A gene
|
Gene
|
Known
|
Explain
|
1.53158
|
|
11
|
Bone remodeling
|
Function
|
Known
|
Explain
|
1.51884
|
|
12
|
Hypercalcemia
|
Disease
|
Known
|
Explain
|
1.34794
|
|
13
|
response to mercury ion
|
Function
|
Known
|
Explain
|
1.25889
|
|
14
|
Hypercalciuria
|
Disease
|
Known
|
Explain
|
1.19238
|
|
15
|
response to cadmium ion
|
Function
|
Known
|
Explain
|
1.14963
|
|
16
|
Ifosfamide
|
Compound
|
Known
|
Explain
|
1.03497
|
|
17
|
phosphate transport
|
Function
|
Known
|
Explain
|
0.95661
|
|
18
|
MAST2 gene
|
Gene
|
Known
|
Explain
|
0.75005
|
|
19
|
brush border membrane
|
Component
|
Known
|
Explain
|
0.71564
|
|
20
|
PEX19 gene
|
Gene
|
Known
|
Explain
|
0.61024
|
|
21
|
Bone Diseases, Developmental
|
Disease
|
Known
|
Explain
|
0.54043
|
|
22
|
SLC9A3R2 gene
|
Gene
|
Known
|
Explain
|
0.48922
|
|
23
|
SLC9A3R1 gene
|
Gene
|
Known
|
Explain
|
0.34266
|
|
24
|
FHL2 gene
|
Gene
|
Known
|
Explain
|
0.33872
|
|
25
|
Alkanesulfonates
|
Compound
|
Inferred
|
Explain
|
0.31443
|
|
26
|
symporter activity
|
Function
|
Known
|
Explain
|
0.24169
|
|
27
|
HSP90AB1 gene
|
Gene
|
Known
|
Explain
|
0.22341
|
|
28
|
SLC34A3 gene
|
Gene
|
Inferred
|
Explain
|
0.21337
|
|
29
|
cellular phosphate ion homeostasis
|
Function
|
Inferred
|
Explain
|
0.19993
|
|
30
|
di-, tri-valent inorganic anion homeostasis
|
Function
|
Inferred
|
Explain
|
0.18018
|
|
31
|
sodium ion transport
|
Function
|
Known
|
Explain
|
0.17590
|
|
32
|
Sulfhydryl Compounds
|
Compound
|
Inferred
|
Explain
|
0.13165
|
|
33
|
Phosphorus Metabolism Disorders
|
Disease
|
Inferred
|
Explain
|
0.12832
|
|
34
|
Familial benign hypercalcemia
|
Disease
|
Inferred
|
Explain
|
0.12793
|
|
35
|
HYPOPHOSPHATEMIC RICKETS, AUTOSOMAL RECESSIVE, 1
|
Disease
|
Inferred
|
Explain
|
0.12667
|
|
36
|
HSP90AA1 gene
|
Gene
|
Known
|
Explain
|
0.12557
|
|
37
|
Autosomal dominant hypophosphatemic rickets
|
Other
|
Inferred
|
Explain
|
0.11625
|
|
38
|
HYPOPHOSPHATEMIA, RENAL, WITH INTRACEREBRAL CALCIFICATIONS
|
Disease
|
Inferred
|
Explain
|
0.11515
|
|
39
|
Orthophosphate
|
Compound
|
Known
|
Explain
|
0.10542
|
|
40
|
Familial hypophosphatemia
|
Disease
|
Inferred
|
Explain
|
0.10321
|
|
41
|
Na/Pi-cotransporter
|
Domain
|
Inferred
|
Explain
|
0.09811
|
|
42
|
Familial hypophosphatemic bone disease
|
Disease
|
Inferred
|
Explain
|
0.08926
|
|
43
|
THYROID HORMONE PLASMA MEMBRANE TRANSPORT DEFECT
|
Disease
|
Inferred
|
Explain
|
0.08703
|
|
44
|
Ion Transport
|
Function
|
Known
|
Explain
|
0.07799
|
|
45
|
SLC34A2 gene
|
Gene
|
Inferred
|
Explain
|
0.07708
|
|
46
|
HYPOCALCIURIC HYPERCALCEMIA, FAMILIAL, TYPE III
|
Disease
|
Inferred
|
Explain
|
0.06909
|
|
47
|
HYPOCALCIURIC HYPERCALCEMIA, FAMILIAL, TYPE II (disorder)
|
Disease
|
Inferred
|
Explain
|
0.06909
|
|
48
|
Hypophosphatemic Rickets
|
Disease
|
Inferred
|
Explain
|
0.06845
|
|
49
|
response to metal ion
|
Function
|
Inferred
|
Explain
|
0.06484
|
|
50
|
SLC17A1 gene
|
Gene
|
Inferred
|
Explain
|
0.06193
|
|
51
|
cellular di-, tri-valent inorganic anion homeostasis
|
Function
|
Inferred
|
Explain
|
0.06161
|
|
52
|
FGF23 gene
|
Gene
|
Inferred
|
Explain
|
0.05949
|
|
53
|
Cystinosis
|
Disease
|
Inferred
|
Explain
|
0.05833
|
|
54
|
Transmembrane Transport
|
Function
|
Known
|
Explain
|
0.05747
|
|
55
|
autosomal recessive hypophosphatemic bone disease
|
Disease
|
Inferred
|
Explain
|
0.05707
|
|
56
|
HYPOURICEMIA, HYPERCALCINURIA, AND DECREASED BONE DENSITY
|
Disease
|
Inferred
|
Explain
|
0.05654
|
|
57
|
Glycogenosis with glucoaminophosphaturia
|
Disease
|
Inferred
|
Explain
|
0.05029
|
|
58
|
Renal Tubular Transport, Inborn Errors
|
Disease
|
Inferred
|
Explain
|
0.04632
|
|
59
|
Secreted phosphoprotein 24
|
Domain
|
Inferred
|
Explain
|
0.04492
|
|
60
|
SFRP4 gene
|
Gene
|
Inferred
|
Explain
|
0.04280
|
|
61
|
SLC20A2 gene
|
Gene
|
Inferred
|
Explain
|
0.04075
|
|
62
|
cellular response to magnesium ion
|
Function
|
Inferred
|
Explain
|
0.03983
|
|
63
|
integral to plasma membrane
|
Component
|
Known
|
Explain
|
0.03950
|
|
64
|
SLC17A7 gene
|
Gene
|
Inferred
|
Explain
|
0.03940
|
|
65
|
sulfate ion homeostasis
|
Function
|
Inferred
|
Explain
|
0.03795
|
|
66
|
Familial idiopathic hypercalciuria
|
Other
|
Inferred
|
Explain
|
0.03788
|
|
67
|
phosphate transmembrane transporter activity
|
Function
|
Inferred
|
Explain
|
0.03706
|
|
68
|
HYPERPARATHYROIDISM, NEONATAL SELF-LIMITED PRIMARY, WITH HYPERCALCIURIA
|
Disease
|
Inferred
|
Explain
|
0.03409
|
|
69
|
Furosemide
|
Compound
|
Inferred
|
Explain
|
0.03270
|
|
70
|
Bartter syndrome, antenatal , type 2
|
Disease
|
Inferred
|
Explain
|
0.03188
|
|
71
|
Blue diaper syndrome
|
Disease
|
Inferred
|
Explain
|
0.03187
|
|
72
|
Bartter syndrome, antenatal type 1
|
Disease
|
Inferred
|
Explain
|
0.03081
|
|
73
|
PROTEINURIA, LOW MOLECULAR WEIGHT, WITH HYPERCALCIURIA AND NEPHROCALCINOSIS
|
Disease
|
Inferred
|
Explain
|
0.03032
|
|
74
|
CTNS gene
|
Gene
|
Inferred
|
Explain
|
0.03029
|
|
75
|
HYPOMAGNESEMIA 5, RENAL, WITH OCULAR INVOLVEMENT
|
Disease
|
Inferred
|
Explain
|
0.02978
|
|
76
|
SLC20A1 gene
|
Gene
|
Inferred
|
Explain
|
0.02732
|
|
77
|
Hrf1
|
Domain
|
Inferred
|
Explain
|
0.02720
|
|
78
|
Hyperphosphatemia
|
Disease
|
Inferred
|
Explain
|
0.02626
|
|
79
|
tissue remodeling
|
Function
|
Inferred
|
Explain
|
0.02510
|
|
80
|
Natural regeneration
|
Function
|
Inferred
|
Explain
|
0.02329
|
|
81
|
SPP2 gene
|
Gene
|
Inferred
|
Explain
|
0.02321
|
|
82
|
Kidney
|
Other
|
Inferred
|
Explain
|
0.02265
|
|
83
|
Primary hypomagnesemia (disorder)
|
Disease
|
Inferred
|
Explain
|
0.02232
|
|
84
|
TNFRSF11B gene
|
Gene
|
Inferred
|
Explain
|
0.02220
|
|
85
|
detoxification of mercury ion
|
Function
|
Inferred
|
Explain
|
0.02212
|
|
86
|
Cell membrane
|
Component
|
Known
|
Explain
|
0.02187
|
|
87
|
anion homeostasis
|
Function
|
Inferred
|
Explain
|
0.02186
|
|
88
|
Urological Manifestations
|
Disease
|
Inferred
|
Explain
|
0.02156
|
|
89
|
Hypouricemia
|
Disease
|
Inferred
|
Explain
|
0.02154
|
|
90
|
Musculoskeletal Physiological Processes
|
Function
|
Inferred
|
Explain
|
0.02035
|
|
91
|
Mercuric resistence transcriptional repressor protein MerD
|
Domain
|
Inferred
|
Explain
|
0.02020
|
|
92
|
cellular response to mercury ion
|
Function
|
Inferred
|
Explain
|
0.01919
|
|
93
|
Hg(II)-responsive transcriptional regulator
|
Domain
|
Inferred
|
Explain
|
0.01888
|
|
94
|
CASR gene
|
Gene
|
Inferred
|
Explain
|
0.01651
|
|
95
|
cellular response to metal ion
|
Function
|
Inferred
|
Explain
|
0.01603
|
|
96
|
Calcium Metabolism Disorders
|
Disease
|
Inferred
|
Explain
|
0.01601
|
|
97
|
MT-CYB gene
|
Gene
|
Inferred
|
Explain
|
0.01576
|
|
98
|
cellular response to cadmium ion
|
Function
|
Inferred
|
Explain
|
0.01522
|
|
99
|
Protein Binding
|
Function
|
Known
|
Explain
|
0.01514
|
|
100
|
Water-Electrolyte Imbalance
|
Disease
|
Inferred
|
Explain
|
0.01503
|