PTGS2 gene

Gene • C1367485

Definition

This gene is involved in mitogenesis, inflammation and angiogenesis.

Synonyms

PTGS2 gene • CYCLOOXYGENASE 2 • PTGS2 • PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2 • PROSTAGLANDIN G/H SYNTHASE 2 • COX2 • PHS II • PGHS2 • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) • Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Gene • GLUCOCORTICOID-REGULATED INFLAMMATORY PROSTAGLANDIN G/H SYNTHASE • GRIPGHS

Linked items?Related concepts, ordered by their global importance in the network.

Cell Nucleus    Cytoplasm    Membrane    Cyclosporine    Metal Ion Binding    7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide    Benzo(a)pyrene    Tetrachlorodibenzodioxin    Estradiol    arsenic trioxide    pirinixic acid    Oxidation-Reduction    Tretinoin    Fluorouracil    tert-Butylhydroperoxide    Endoplasmic Reticulum    TP53 gene    decitabine    Progesterone    Water   

Related concepts

# Concept name Type Relation Support Score
1 PTGS1 gene Gene Inferred Explain 0.05042
2 Prostaglandin G2 Compound Known Explain 0.02692
3 IL1B gene Gene Inferred Explain 0.02655
4 prostaglandin D3 Compound Known Explain 0.02599
5 prostaglandin E3 Compound Known Explain 0.02599
6 prostaglandin I3 Compound Known Explain 0.02599
7 2,2-di(4-methacryloxyphenyl)propane Compound Known Explain 0.02591
8 Adaptic Compound Known Explain 0.02591
9 6-formylindolo(3,2-b)carbazole Compound Known Explain 0.02584
10 2,4,2',4'-tetrachlorobiphenyl Compound Known Explain 0.02534
11 LE 540 Compound Known Explain 0.02534
12 4-(4-cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide Compound Known Explain 0.02530
13 dentinol Compound Known Explain 0.02528
14 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline Compound Known Explain 0.02484
15 Thromboxane B2 Compound Known Explain 0.02456
16 GW 1929 Compound Known Explain 0.02433
17 manoalide Compound Known Explain 0.02411
18 cyclooxygenase pathway Function Known Explain 0.02411
19 Mannans Compound Known Explain 0.02410
20 CR 3294 Compound Known Explain 0.02405
21 flavanone Compound Known Explain 0.02404
22 avarol Compound Known Explain 0.02400
23 triethylene glycol dimethacrylate Compound Known Explain 0.02399
24 lornoxicam Compound Known Explain 0.02346
25 prostaglandin-endoperoxide synthase activity Function Known Explain 0.02336
26 resorcinol Compound Known Explain 0.02320
27 Carcinoma in Situ Disease Known Explain 0.02268
28 Biosept Compound Known Explain 0.02253
29 licochalcone A Compound Known Explain 0.02217
30 8-epi-prostaglandin F2alpha Compound Known Explain 0.02209
31 WEB 2086 Compound Known Explain 0.02201
32 1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole Compound Known Explain 0.02200
33 12-(acetyloxy)-4,4,8-trimethylhomoandrost-16-ene-17,17a-dicarboxaldehyde Compound Known Explain 0.02197
34 positive regulation of synaptic plasticity Function Known Explain 0.02176
35 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole Compound Known Explain 0.02158
36 quercetin 3'-sulfate Compound Known Explain 0.02095
37 valdecoxib Compound Known Explain 0.02081
38 4-coumaric acid Compound Known Explain 0.02033
39 glyceryl nonivamide Compound Known Explain 0.02004
40 indomethacin phenethylamide Compound Known Explain 0.02004
41 amentoflavone Compound Known Explain 0.01990
42 REV 5901 Compound Known Explain 0.01985
43 S,S'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea Compound Known Explain 0.01970
44 2-amino-3-methylimidazo(4,5-f)quinoline Compound Known Explain 0.01969
45 negative regulation of synaptic transmission, dopaminergic Function Known Explain 0.01932
46 tephrosin Compound Known Explain 0.01929
47 etoricoxib Compound Known Explain 0.01914
48 Hesperidin Compound Known Explain 0.01894
49 gamma-Tocopherol Compound Known Explain 0.01892
50 EGTA acetoxymethyl ester Compound Known Explain 0.01888
51 Benzoyl Peroxide Compound Known Explain 0.01887
52 Fluanxol Compound Known Explain 0.01886
53 positive regulation of fibroblast growth factor production Function Known Explain 0.01871
54 meloxicam Compound Known Explain 0.01851
55 TNF gene Gene Inferred Explain 0.01844
56 Phenetidine Compound Known Explain 0.01835
57 lipopolysaccharide, E. coli 026-B6 Compound Known Explain 0.01832
58 methyl arachidonylfluorophosphonate Compound Known Explain 0.01800
59 benzidine Compound Known Explain 0.01786
60 SCUTELLARIA BAICALENSIS Extract Compound Known Explain 0.01785
61 leiomyosarcoma Disease Known Explain 0.01779
62 Potassium Iodide Compound Known Explain 0.01769
63 chan su Compound Known Explain 0.01757
64 Ketorolac Compound Known Explain 0.01745
65 prostaglandin metabolic process Function Known Explain 0.01727
66 positive regulation of transforming growth factor-beta production Function Known Explain 0.01721
67 bisperoxovanadium Compound Known Explain 0.01683
68 vinorelbine Compound Known Explain 0.01673
69 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid Compound Known Explain 0.01645
70 2-aminoethoxydiphenyl borate Compound Known Explain 0.01614
71 positive regulation of cell migration involved in sprouting angiogenesis Function Known Explain 0.01600
72 arachidonyltrifluoromethane Compound Known Explain 0.01600
73 Folfox protocol Other Known Explain 0.01587
74 positive regulation of synaptic transmission, glutamatergic Function Known Explain 0.01582
75 positive regulation of prostaglandin biosynthetic process Function Known Explain 0.01548
76 COX 189 Compound Known Explain 0.01537
77 Ammonium Phosphatidate Compound Known Explain 0.01531
78 Flufenamic Acid Compound Known Explain 0.01518
79 PD 169316 Compound Known Explain 0.01505
80 Arecoline Compound Known Explain 0.01498
81 Allergic rhinitis (disorder) Disease Known Explain 0.01494
82 AGN 193109 Compound Known Explain 0.01442
83 prostanoid metabolic process Function Known Explain 0.01442
84 3,4,3',4'-tetrachlorobiphenyl Compound Known Explain 0.01435
85 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Compound Known Explain 0.01425
86 anagen Function Known Explain 0.01419
87 Intestinal Polyps Other Known Explain 0.01418
88 FEC protocol Other Known Explain 0.01412
89 prostaglandin biosynthetic process Function Known Explain 0.01406
90 response to manganese ion Function Known Explain 0.01373
91 xanthohumol Compound Known Explain 0.01354
92 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Compound Known Explain 0.01349
93 Coal Tar Compound Known Explain 0.01342
94 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Compound Known Explain 0.01331
95 Paroxetine Compound Known Explain 0.01325
96 Ro 31-8220 Compound Known Explain 0.01316
97 BAY 11-7085 Compound Known Explain 0.01311
98 Platinum Compound Known Explain 0.01308
99 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole Compound Known Explain 0.01267
100 benzo(a)pyrene 7,8-dihydrodiol Compound Known Explain 0.01257