EPO gene

Gene • C1366564

Definition

This gene is involved in the regulation of red blood cell production and function.

Synonyms

EPO gene • ERYTHROPOIETIN • EP • EPO • Erythropoietin Gene

Linked items?Related concepts, ordered by their global importance in the network.

Protein Binding    Cyclosporine    Benzo(a)pyrene    extracellular region    Signal Transduction    Fluorouracil    decitabine    Extracellular Space    bisphenol A    Apoptosis    Quercetin    Curcumin    Hydrogen Peroxide    Stimulation of Cell Proliferation    Cytokine-cytokine receptor interaction - Homo sapiens (human)    regulation of transcription from RNA polymerase II promoter    melanoma    Plant Extracts    Jak-STAT signaling pathway - Homo sapiens (human)    hormone activity   

Related concepts

# Concept name Type Relation Support Score
1 Erythropoietin Domain Known Explain 1.68589
2 erythropoietin receptor binding activity Function Known Explain 1.10982
3 Erythropoietin/thrombopoeitin, conserved site Domain Known Explain 1.03347
4 Erythropoietin/thrombopoeitin Domain Known Explain 1.02388
5 erythrocyte maturation Function Known Explain 0.47448
6 Th-1165a Compound Known Explain 0.46606
7 Amitrole Compound Known Explain 0.46579
8 hemoglobin biosynthetic process Function Known Explain 0.46564
9 Clioquinol Compound Known Explain 0.33670
10 response to vitamin A Function Known Explain 0.32645
11 Kidney Failure, Chronic Disease Known Explain 0.30062
12 Cobalt Compound Known Explain 0.29686
13 positive regulation of tyrosine phosphorylation of Stat5 protein Function Known Explain 0.29081
14 IPR012351 Domain Known Explain 0.28426
15 response to hyperoxia Disease Known Explain 0.28053
16 Neuroprotection Function Known Explain 0.26216
17 salinity response Function Known Explain 0.26153
18 response to axon injury Function Known Explain 0.25061
19 apple polyphenol extract Compound Known Explain 0.24762
20 response to testosterone stimulus Function Known Explain 0.22985
21 response to electrical stimulus Function Known Explain 0.22735
22 Degenerative Diseases, Central Nervous System Disease Known Explain 0.22254
23 response to interleukin-1 Function Known Explain 0.22174
24 positive regulation of Ras protein signal transduction Function Known Explain 0.21365
25 Four-helical cytokine-like, core Domain Known Explain 0.21144
26 erythrocyte differentiation Function Known Explain 0.21008
27 Blastocyst Implantation, natural Function Known Explain 0.20495
28 DOK2 gene Gene Known Explain 0.19096
29 Cardiomyopathies, Primary Disease Known Explain 0.18126
30 CNS disorder Disease Known Explain 0.18073
31 Manganese Compound Known Explain 0.15711
32 positive regulation of DNA replication Function Known Explain 0.15698
33 Deferoxamine Compound Known Explain 0.15585
34 Anemia Disease Known Explain 0.14949
35 positive regulation of neuron differentiation Function Known Explain 0.14644
36 Dacarbazine Compound Known Explain 0.14362
37 response to estrogen stimulus Function Known Explain 0.12373
38 Poisoning Other Known Explain 0.11821
39 positive regulation of gene-specific transcription Function Known Explain 0.11342
40 Blood Circulation Function Known Explain 0.11024
41 cobaltous chloride Compound Known Explain 0.10985
42 EPOR gene Gene Known Explain 0.09929
43 Heart Diseases Disease Known Explain 0.09887
44 Hematopoietic cell lineage - Homo sapiens (human) Pathway Known Explain 0.08519
45 2-Naphthylamine Compound Known Explain 0.08160
46 Thrombopoeitin Domain Inferred Explain 0.08029
47 Vitamin K 3 Compound Known Explain 0.07631
48 response to nutrient Function Known Explain 0.07270
49 Vitamin A Compound Known Explain 0.07233
50 hormone activity Function Known Explain 0.07066
51 Aging Function Known Explain 0.06831
52 response to lipopolysaccharide Function Known Explain 0.06725
53 Nicotine Compound Known Explain 0.06576
54 Jak-STAT signaling pathway - Homo sapiens (human) Pathway Known Explain 0.05711
55 response to hypoxia Function Known Explain 0.05308
56 Plant Extracts Compound Known Explain 0.03915
57 Cytokine-cytokine receptor interaction - Homo sapiens (human) Pathway Known Explain 0.03776
58 Cytokine Receptor Binding Function Inferred Explain 0.03227
59 melanoma Disease Known Explain 0.03156
60 Hydrogen Peroxide Compound Known Explain 0.02965
61 TPO gene Gene Inferred Explain 0.02902
62 regulation of transcription from RNA polymerase II promoter Function Known Explain 0.02645
63 Stimulation of Cell Proliferation Function Known Explain 0.02552
64 Curcumin Compound Known Explain 0.02050
65 Quercetin Compound Known Explain 0.01906
66 extracellular region Component Known Explain 0.01874
67 hemoglobin metabolic process Function Inferred Explain 0.01685
68 Extracellular Space Other Known Explain 0.01480
69 Apoptosis Function Known Explain 0.01478
70 bisphenol A Compound Known Explain 0.01367
71 HBZ gene Gene Inferred Explain 0.01297
72 decitabine Compound Known Explain 0.01281
73 Fluorouracil Compound Known Explain 0.01098
74 Signal Transduction Function Known Explain 0.01077
75 Triazoles Compound Inferred Explain 0.01075
76 cellular macromolecule biosynthetic process Function Inferred Explain 0.01066
77 MAEA gene Gene Inferred Explain 0.00839
78 ALAS2 gene Gene Inferred Explain 0.00826
79 Malondialdehyde Compound Inferred Explain 0.00792
80 INHA gene Gene Inferred Explain 0.00763
81 Benzo(a)pyrene Compound Known Explain 0.00717
82 Protein Binding Function Known Explain 0.00710
83 CAT gene Gene Inferred Explain 0.00699
84 MUC5AC gene Gene Inferred Explain 0.00692
85 Cell Maturation Function Inferred Explain 0.00636
86 IL3 gene Gene Inferred Explain 0.00634
87 Cyclosporine Compound Known Explain 0.00619
88 EPB42 gene Gene Inferred Explain 0.00608
89 Chronic Kidney Insufficiency Disease Inferred Explain 0.00561
90 INHBA gene Gene Inferred Explain 0.00534
91 Frasier Syndrome Disease Inferred Explain 0.00506
92 LEP gene Gene Inferred Explain 0.00485
93 HAMP gene Gene Inferred Explain 0.00429
94 C1858959 Other Inferred Explain 0.00413
95 High Pressure Neurological Syndrome Disease Inferred Explain 0.00405
96 regulation of tyrosine phosphorylation of Stat5 protein Function Inferred Explain 0.00400
97 MAPK1 gene Gene Inferred Explain 0.00393
98 MAPK3 gene Gene Inferred Explain 0.00393
99 Pneumocephalus Disease Inferred Explain 0.00388
100 Dichlorvos Compound Inferred Explain 0.00385