Definition: This gene plays a role in cell growth, proliferation and biogenesis/organization. It is also involved in the inhibition of apoptosis.[...]
Synonyms: TGFB1 gene • TGF-BETA • Camurati-Engelmann disease • CED • TRANSFORMING GROWTH FACTOR, BETA-1 • Transforming growth factor beta 1 • transforming growth factor, beta 1 • TGFB • TGFB1 • Transforming Growth Factor, Beta 1 (Camurati-Engelmann Disease) Gene • TGFbeta
#
|
Entity
|
Type
|
Relation
|
Support
|
Relative specificity
|
1
|
2',4'-dichlorobenzamil amiloride
|
Compound
|
Known
|
Explain
|
|
2
|
zinc mesoporphyrin
|
Compound
|
Known
|
Explain
|
|
3
|
protoporphyrinogen
|
Compound
|
Known
|
Explain
|
|
4
|
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide
|
Compound
|
Known
|
Explain
|
|
5
|
GW 6604
|
Compound
|
Known
|
Explain
|
|
6
|
ossification involved in bone remodeling
|
Function
|
Known
|
Explain
|
|
7
|
dimethyl mercaptosuccinate
|
Compound
|
Known
|
Explain
|
|
8
|
Transforming growth factor, beta 1
|
Domain
|
Known
|
Explain
|
|
9
|
frontal suture morphogenesis
|
Function
|
Known
|
Explain
|
|
10
|
mammary gland duct branch elongation
|
Function
|
Known
|
Explain
|
|
11
|
lens fiber cell differentiation
|
Function
|
Known
|
Explain
|
|
12
|
benazepril
|
Compound
|
Known
|
Explain
|
|
13
|
connective tissue replacement during inflammatory response
|
Function
|
Known
|
Explain
|
|
14
|
Transforming growth factor-beta
|
Domain
|
Known
|
Explain
|
|
15
|
(S)-3-(8-(dimethylaminomethyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione hydrochloride
|
Compound
|
Known
|
Explain
|
|
16
|
negative regulation of release of sequestered calcium ion into cytosol
|
Function
|
Known
|
Explain
|
|
17
|
active induction of host immune response by virus
|
Function
|
Known
|
Explain
|
|
18
|
positive regulation of smooth muscle cell differentiation
|
Function
|
Known
|
Explain
|
|
19
|
type II transforming growth factor beta receptor binding
|
Function
|
Known
|
Explain
|
|
20
|
positive regulation of fibroblast migration
|
Function
|
Known
|
Explain
|
|
21
|
SMAD protein nuclear translocation
|
Function
|
Known
|
Explain
|
|
22
|
defense response to fungus, incompatible interaction
|
Function
|
Known
|
Explain
|
|
23
|
Triamcinolone Acetonide
|
Compound
|
Known
|
Explain
|
|
24
|
macrophage derived foam cell differentiation
|
Function
|
Known
|
Explain
|
|
25
|
Camurati-Engelmann Syndrome
|
Other
|
Known
|
Explain
|
|
26
|
negative regulation of neuroblast proliferation
|
Function
|
Known
|
Explain
|
|
27
|
mononuclear cell proliferation
|
Function
|
Known
|
Explain
|
|
28
|
response to cholesterol
|
Function
|
Known
|
Explain
|
|
29
|
protocatechualdehyde
|
Compound
|
Known
|
Explain
|
|
30
|
halofuginone
|
Compound
|
Known
|
Explain
|
|
31
|
positive regulation of exit from mitosis
|
Function
|
Known
|
Explain
|
|
32
|
positive regulation of isotype switching to IgA isotypes
|
Function
|
Known
|
Explain
|
|
33
|
F2-Isoprostanes
|
Compound
|
Known
|
Explain
|
|
34
|
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate
|
Compound
|
Known
|
Explain
|
|
35
|
mammary gland branching involved in thelarche
|
Function
|
Known
|
Explain
|
|
36
|
SMAD protein complex assembly
|
Function
|
Known
|
Explain
|
|
37
|
ebselen
|
Compound
|
Known
|
Explain
|
|
38
|
regulation of DNA binding
|
Function
|
Known
|
Explain
|
|
39
|
positive regulation of peptidyl-threonine phosphorylation
|
Function
|
Known
|
Explain
|
|
40
|
transforming growth factor beta receptor binding
|
Function
|
Known
|
Explain
|
|
41
|
negative regulation of macrophage cytokine production
|
Function
|
Known
|
Explain
|
|
42
|
regulatory T cell differentiation
|
Function
|
Known
|
Explain
|
|
43
|
regulation of binding
|
Function
|
Known
|
Explain
|
|
44
|
regulation of branching involved in mammary gland duct morphogenesis
|
Function
|
Known
|
Explain
|
|
45
|
positive regulation of odontogenesis
|
Function
|
Known
|
Explain
|
|
46
|
germ cell migration
|
Function
|
Known
|
Explain
|
|
47
|
pathway-restricted SMAD protein phosphorylation
|
Function
|
Known
|
Explain
|
|
48
|
response to laminar fluid shear stress
|
Function
|
Known
|
Explain
|
|
49
|
WFIKKN1 gene
|
Gene
|
Known
|
Explain
|
|
50
|
positive regulation of phosphoinositide 3-kinase activity
|
Function
|
Known
|
Explain
|
|
51
|
WFIKKN2 gene
|
Gene
|
Known
|
Explain
|
|
52
|
positive regulation of SMAD protein nuclear translocation
|
Function
|
Known
|
Explain
|
|
53
|
positive regulation of cell cycle arrest
|
Function
|
Known
|
Explain
|
|
54
|
Ro 31-8220
|
Compound
|
Known
|
Explain
|
|
55
|
positive regulation of protein amino acid dephosphorylation
|
Function
|
Known
|
Explain
|
|
56
|
tolerance induction to self antigen
|
Function
|
Known
|
Explain
|
|
57
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Compound
|
Known
|
Explain
|
|
58
|
cellular response to dexamethasone stimulus
|
Function
|
Known
|
Explain
|
|
59
|
lymph node development
|
Function
|
Known
|
Explain
|
|
60
|
hemopoietic progenitor cell differentiation
|
Function
|
Known
|
Explain
|
|
61
|
positive regulation of blood vessel endothelial cell migration
|
Function
|
Known
|
Explain
|
|
62
|
receptor catabolic process
|
Function
|
Known
|
Explain
|
|
63
|
negative regulation of blood vessel endothelial cell migration
|
Function
|
Known
|
Explain
|
|
64
|
positive regulation of branching involved in ureteric bud morphogenesis
|
Function
|
Known
|
Explain
|
|
65
|
BMP3 gene
|
Gene
|
Known
|
Explain
|
|
66
|
salivary gland morphogenesis
|
Function
|
Known
|
Explain
|
|
67
|
positive regulation of histone deacetylation
|
Function
|
Known
|
Explain
|
|
68
|
DPT gene
|
Gene
|
Known
|
Explain
|
|
69
|
negative regulation of phagocytosis
|
Function
|
Known
|
Explain
|
|
70
|
TGFBRAP1 gene
|
Gene
|
Known
|
Explain
|
|
71
|
negative regulation of ossification
|
Function
|
Known
|
Explain
|
|
72
|
G1/S transition checkpoint
|
Function
|
Known
|
Explain
|
|
73
|
T cell homeostasis
|
Function
|
Known
|
Explain
|
|
74
|
DIP2A gene
|
Gene
|
Known
|
Explain
|
|
75
|
regulation of sodium ion transport
|
Function
|
Known
|
Explain
|
|
76
|
morphogenesis of a branching structure
|
Function
|
Known
|
Explain
|
|
77
|
Berylliosis
|
Other
|
Known
|
Explain
|
|
78
|
Transforming growth factor beta (TGFb), N-terminal
|
Domain
|
Known
|
Explain
|
|
79
|
FMOD gene
|
Gene
|
Known
|
Explain
|
|
80
|
myeloid dendritic cell differentiation
|
Function
|
Known
|
Explain
|
|
81
|
positive regulation of pathway-restricted SMAD protein phosphorylation
|
Function
|
Known
|
Explain
|
|
82
|
evasion of host defenses by virus
|
Function
|
Known
|
Explain
|
|
83
|
FCN1 gene
|
Gene
|
Known
|
Explain
|
|
84
|
regulation of protein import into nucleus
|
Function
|
Known
|
Explain
|
|
85
|
positive regulation of interleukin-17 production
|
Function
|
Known
|
Explain
|
|
86
|
regulation of striated muscle tissue development
|
Function
|
Known
|
Explain
|
|
87
|
Transforming growth factor beta, conserved site
|
Domain
|
Known
|
Explain
|
|
88
|
Sarcoidosis
|
Disease
|
Known
|
Explain
|
|
89
|
Chronic Obstructive Airway Disease
|
Disease
|
Known
|
Explain
|
|
90
|
positive regulation of collagen biosynthetic process
|
Function
|
Known
|
Explain
|
|
91
|
VASN gene
|
Gene
|
Known
|
Explain
|
|
92
|
chondrocyte differentiation
|
Function
|
Known
|
Explain
|
|
93
|
regulation of transforming growth factor beta receptor signaling pathway
|
Function
|
Known
|
Explain
|
|
94
|
Transforming growth factor-beta-related
|
Domain
|
Known
|
Explain
|
|
95
|
TGFB3 gene
|
Gene
|
Inferred
|
Explain
|
|
96
|
positive regulation of histone acetylation
|
Function
|
Known
|
Explain
|
|
97
|
Oral Submucous Fibrosis
|
Disease
|
Known
|
Explain
|
|
98
|
TGFB2 gene
|
Gene
|
Known
|
Explain
|
|
99
|
Pyemia
|
Disease
|
Known
|
Explain
|
|
100
|
negative regulation of mitotic cell cycle
|
Function
|
Known
|
Explain
|
|