GRK1 gene

Gene • C1335620

Definition

This gene is involved in sensory transduction necessary for vision.

Synonyms

GRK1 gene • RHODOPSIN KINASE • GRK1 • RHOK • RK • G protein-coupled receptor kinase 1 • G Protein-Coupled Receptor Kinase 1 Gene • GPRK1 • G PROTEIN-DEPENDENT RECEPTOR KINASE 1 • OGUCHI DISEASE 2

Linked items?Related concepts, ordered by their global importance in the network.

Membrane    ATP binding    nucleotide binding    Adenosine Triphosphate    sodium arsenite    Adenosine Diphosphate    Response to stimulus physiology    signal transducer activity    drug response    CALM1 gene    CAV1 gene    Vision    Endocytosis - Homo sapiens (human)    protein kinase activity    Chemokine signaling pathway - Homo sapiens (human)    SNCA gene    protein amino acid autophosphorylation    regulation of G-protein coupled receptor protein signaling pathway    PDE6D gene    RHO gene   

Related concepts

# Concept name Type Relation Support Score
1 Phosphorhodopsin Compound Known Explain 4.07469
2 rhodopsin kinase activity Function Known Explain 3.94847
3 rhodopsin mediated signaling pathway Function Known Explain 3.50303
4 Oguchi disease Disease Known Explain 3.30963
5 rhodopsin mediated phototransduction Function Known Explain 2.62925
6 G-protein coupled receptor kinase activity Function Known Explain 2.54157
7 Rhodopsin Compound Known Explain 2.19198
8 RHO gene Gene Known Explain 2.09321
9 RCVRN gene Gene Known Explain 1.84348
10 SNCB gene Gene Known Explain 1.50056
11 KEGG:hsa04744 Known Explain 1.36081
12 SAG gene Gene Inferred Explain 1.29433
13 GRK7 gene Gene Inferred Explain 1.13376
14 SNCG gene Gene Known Explain 0.96253
15 PDE6D gene Gene Known Explain 0.77941
16 response to light stimulus Function Known Explain 0.76156
17 regulation of G-protein coupled receptor protein signaling pathway Function Known Explain 0.50113
18 protein kinase activity Function Known Explain 0.47718
19 protein amino acid autophosphorylation Function Known Explain 0.46098
20 Night Blindness Disease Inferred Explain 0.29493
21 Chemokine signaling pathway - Homo sapiens (human) Pathway Known Explain 0.23718
22 Vision Function Known Explain 0.23424
23 SNCA gene Gene Known Explain 0.21715
24 Endocytosis - Homo sapiens (human) Pathway Known Explain 0.21063
25 CALM1 gene Gene Known Explain 0.17932
26 CAV1 gene Gene Known Explain 0.17608
27 GRK6 gene Gene Inferred Explain 0.15972
28 drug response Function Known Explain 0.14357
29 signal transducer activity Function Known Explain 0.13769
30 GRK5 gene Gene Inferred Explain 0.12653
31 phototransduction, visible light Function Inferred Explain 0.11236
32 Response to stimulus physiology Function Known Explain 0.09301
33 GPCR kinase Domain Inferred Explain 0.08659
34 Adenosine Diphosphate Compound Known Explain 0.07887
35 GNAT1 gene Gene Inferred Explain 0.06991
36 visual perception, sensory transduction of light stimulus Function Inferred Explain 0.06772
37 Adenosine Triphosphate Compound Known Explain 0.06137
38 GNAT2 gene Gene Inferred Explain 0.05845
39 sodium arsenite Compound Known Explain 0.05476
40 Rod Opsins Compound Inferred Explain 0.05447
41 GNAT3 gene Gene Inferred Explain 0.04805
42 GRK4 gene Gene Inferred Explain 0.04801
43 ADRBK1 gene Gene Inferred Explain 0.03852
44 nucleotide binding Function Known Explain 0.03376
45 ADRBK2 gene Gene Inferred Explain 0.03368
46 ATP binding Function Known Explain 0.02901
47 calcium sensitive guanylate cyclase activator activity Function Inferred Explain 0.02599
48 NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 1 Disease Inferred Explain 0.02039
49 G-Protein-Coupled Receptors Compound Inferred Explain 0.01567
50 Light Signal Transduction Function Inferred Explain 0.01549
51 Membrane Component Known Explain 0.01471
52 G-protein coupled receptor protein signaling pathway Function Inferred Explain 0.01221
53 Lewy Body Disease Disease Inferred Explain 0.01198
54 CENPT gene Gene Inferred Explain 0.01120
55 photoreceptor outer segment membrane Component Inferred Explain 0.01078
56 photoreceptor inner segment membrane Component Inferred Explain 0.01049
57 GNGT1 gene Gene Inferred Explain 0.00945
58 regulation of calcium ion transport Function Inferred Explain 0.00941
59 dopamine metabolic process Function Inferred Explain 0.00920
60 NPH3 Domain Inferred Explain 0.00908
61 phospholipase inhibitor activity Function Inferred Explain 0.00801
62 photoreceptor inner segment Component Inferred Explain 0.00792
63 detection of light stimulus Function Inferred Explain 0.00753
64 Pigment-dispersing hormone Domain Inferred Explain 0.00750
65 PQBP1 gene Gene Inferred Explain 0.00691
66 GJA10 gene Gene Inferred Explain 0.00676
67 photoreceptor outer segment Component Inferred Explain 0.00666
68 phototaxis Function Inferred Explain 0.00666
69 SEPT4 gene Gene Inferred Explain 0.00648
70 photoperiodism Function Inferred Explain 0.00631
71 GUCA1C gene Gene Inferred Explain 0.00608
72 Regulator of G protein signalling Domain Inferred Explain 0.00603
73 FUNDUS ALBIPUNCTATUS Disease Inferred Explain 0.00596
74 protein serine/threonine kinase activity Function Inferred Explain 0.00593
75 response to red or far red light Function Inferred Explain 0.00588
76 AGC-kinase, C-terminal Domain Inferred Explain 0.00571
77 photoreceptor activity Function Inferred Explain 0.00568
78 Regulator of G protein signalling superfamily Domain Inferred Explain 0.00555
79 PDE6B gene Gene Inferred Explain 0.00554
80 Presynaptic Terminals Component Inferred Explain 0.00525
81 response to blue light Function Inferred Explain 0.00525
82 cellular response to light stimulus Function Inferred Explain 0.00518
83 FAM90A16 gene Gene Inferred Explain 0.00499
84 protein amino acid phosphorylation Function Inferred Explain 0.00493
85 response to light intensity Function Inferred Explain 0.00483
86 GUCA1A gene Gene Inferred Explain 0.00471
87 visual behavior Other Inferred Explain 0.00459
88 GUCA1B gene Gene Inferred Explain 0.00447
89 detection of visible light Function Inferred Explain 0.00443
90 ARR3 gene Gene Inferred Explain 0.00426
91 opsin binding Function Inferred Explain 0.00420
92 Cell membrane Component Inferred Explain 0.00410
93 negative regulation of neuron apoptosis Function Inferred Explain 0.00378
94 Protein Binding Function Inferred Explain 0.00372
95 Opsins Compound Inferred Explain 0.00368
96 Retinitis Pigmentosa Disease Inferred Explain 0.00362
97 Cytoplasm Component Inferred Explain 0.00360
98 RGS9 gene Gene Inferred Explain 0.00327
99 NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 3 Disease Inferred Explain 0.00326
100 calcium ion binding Function Inferred Explain 0.00317