PTGS1 gene

Gene • C1335271

Definition

This gene plays a role in the regulation of angiogenesis in endothelial cells.

Synonyms

PTGS1 gene • CYCLOOXYGENASE 1 • PGHS-1 • PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1 • PROSTAGLANDIN G/H SYNTHASE 1 • COX1 • PGHS1 • PTGHS • PTGS1 • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) • Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) Gene

Linked items?Related concepts, ordered by their global importance in the network.

Cell Nucleus    Cytoplasm    Cell membrane    Metal Ion Binding    Estradiol    Oxidation-Reduction    Tretinoin    Endoplasmic Reticulum    Golgi Apparatus    Progesterone    Water    Calcitriol    bisphenol A    oxidoreductase activity    Endoplasmic reticulum, membrane    resveratrol    Quercetin    Cisplatin    Indomethacin    Tetradecanoylphorbol Acetate   

Related concepts

# Concept name Type Relation Support Score
1 Aminopyrine Compound Known Explain 0.52705
2 Dipyrone Compound Known Explain 0.47304
3 Antipyrine Compound Known Explain 0.33803
4 Prostaglandin G2 Compound Known Explain 0.31335
5 CD32 Antigens Compound Known Explain 0.30258
6 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline Compound Known Explain 0.28795
7 7-(deoxyadenosin-N(6)-yl)aristolactam I Compound Known Explain 0.28335
8 cyclooxygenase pathway Function Known Explain 0.27972
9 prostaglandin-endoperoxide synthase activity Function Known Explain 0.27152
10 lornoxicam Compound Known Explain 0.26614
11 Pyrazolones Compound Inferred Explain 0.25064
12 licochalcone A Compound Known Explain 0.24968
13 2-amino-3-methylimidazo(4,5-f)quinoline Compound Known Explain 0.22480
14 Fluanxol Compound Known Explain 0.21551
15 negative regulation of epinephrine secretion Function Known Explain 0.21201
16 negative regulation of norepinephrine secretion Function Known Explain 0.20978
17 Ketorolac Compound Known Explain 0.19993
18 chan su Compound Known Explain 0.19772
19 benzidine Compound Known Explain 0.19557
20 CD23 Antigen Compound Known Explain 0.17837
21 Sleep Deprivation Disease Known Explain 0.16675
22 Intestinal Polyps Other Known Explain 0.15817
23 PTGS2 gene Gene Inferred Explain 0.15697
24 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Compound Known Explain 0.14967
25 Prostaglandin H2 Compound Known Explain 0.13800
26 benzo(a)pyrene 7,8-dihydrodiol Compound Known Explain 0.13745
27 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole Compound Known Explain 0.13699
28 prostanoid metabolic process Function Known Explain 0.13518
29 Bupivacaine Compound Known Explain 0.13240
30 prostaglandin biosynthetic process Function Known Explain 0.13030
31 Aplastic Anemia Disease Known Explain 0.12256
32 Phenacetin Compound Known Explain 0.11485
33 Smoke Compound Known Explain 0.10989
34 nimesulide Compound Known Explain 0.10675
35 Methylenebis(chloroaniline) Compound Known Explain 0.10496
36 NUCB1 gene Gene Known Explain 0.10368
37 positive regulation of smooth muscle contraction Function Known Explain 0.10162
38 positive regulation of vasoconstriction Function Known Explain 0.09746
39 response to corticosterone stimulus Function Known Explain 0.09743
40 4-biphenylamine Compound Known Explain 0.09457
41 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine Compound Known Explain 0.09139
42 cotylenin A Compound Known Explain 0.09107
43 Flurbiprofen Compound Known Explain 0.08770
44 Synflex Compound Known Explain 0.07927
45 response to organic nitrogen Function Known Explain 0.07475
46 4-phenylenediamine Compound Known Explain 0.07226
47 Platelet Activating Factor Compound Known Explain 0.06932
48 NS 398 Compound Known Explain 0.06817
49 Butyric Acid Compound Known Explain 0.06074
50 SC 58635 Compound Known Explain 0.05814
51 Diclofenac Compound Known Explain 0.05804
52 paricalcitol Compound Known Explain 0.05265
53 peroxidase activity Function Known Explain 0.05044
54 Arachidonic Acid Metabolism Pathway Function Known Explain 0.04842
55 blood pressure regulation Function Known Explain 0.04259
56 Dinoprostone Compound Known Explain 0.03995
57 Phosphorus Compound Known Explain 0.03928
58 ALOX5 gene Gene Inferred Explain 0.03908
59 rofecoxib Compound Known Explain 0.03877
60 Reactive Oxygen Species Compound Known Explain 0.03596
61 Acetaldehyde Compound Known Explain 0.03532
62 Acceptor Compound Known Explain 0.03317
63 Reduced acceptor Compound Known Explain 0.03317
64 hormone biosynthetic process Function Known Explain 0.03210
65 candoxin Compound Known Explain 0.03044
66 4-oxoretinoic acid Compound Known Explain 0.03011
67 Aging Function Known Explain 0.02905
68 Thalidomide Compound Known Explain 0.02878
69 fatty acid biosynthetic process Function Known Explain 0.02518
70 Isotretinoin Compound Known Explain 0.02479
71 Acetaco Compound Known Explain 0.02452
72 arachidonic acid metabolic process Function Inferred Explain 0.02450
73 Arachidonic Acid Compound Known Explain 0.02392
74 Cell Proliferation Regulation Function Known Explain 0.02386
75 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Function Known Explain 0.02349
76 negative regulation of catecholamine secretion Function Inferred Explain 0.02331
77 response to oxidative stress Function Known Explain 0.02320
78 Ibuprofen Compound Known Explain 0.02275
79 gemcitabine Compound Known Explain 0.02146
80 CYP1A2 gene Gene Inferred Explain 0.01888
81 Aloxiprimum Compound Known Explain 0.01814
82 alitretinoin Compound Known Explain 0.01772
83 Xenobiotic Metabolism Function Known Explain 0.01733
84 Dexamethasone Compound Known Explain 0.01699
85 sulindac sulfide Compound Known Explain 0.01693
86 Lipid Binding Function Known Explain 0.01669
87 Fever Disease Inferred Explain 0.01666
88 Fc Receptor Compound Inferred Explain 0.01655
89 Ethinyl Estradiol Compound Known Explain 0.01646
90 Oxygen Compound Known Explain 0.01629
91 Nuclear Envelope Component Known Explain 0.01583
92 Microsomes Component Known Explain 0.01521
93 trichostatin A Compound Known Explain 0.01512
94 Indomethacin Compound Known Explain 0.01434
95 Mifepristone Compound Known Explain 0.01385
96 ADRA2B gene Gene Inferred Explain 0.01372
97 heme binding Function Known Explain 0.01310
98 PTGIS gene Gene Inferred Explain 0.01286
99 Tetradecanoylphorbol Acetate Compound Known Explain 0.01272
100 Lipid Metabolism Function Known Explain 0.01264