integral to plasma membrane

Component • C1167220

Definition

Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. [GOC:go_curators]

Synonyms

There are no synonyms of this concept in our database.

Linked items?Related concepts, ordered by their global importance in the network.

integral to membrane    TNF gene    HLA-B gene    APP gene    INSR gene    CAV1 gene    IGF1R gene    PSEN1 gene    ICAM1 gene    TNFRSF1A gene    ERBB3 gene    FASLG gene    ABCC1 gene    ADRB2 gene    FGFR1 gene    TLR4 gene    DRD2 gene    ABCA1 gene    ABCC2 gene    PDGFRB gene   

Related concepts

# Concept name Type Relation Support Score
1 Cell membrane Component Inferred Explain 0.02993
2 receptor activity Function Inferred Explain 0.01673
3 Sodium:neurotransmitter symporter Domain Known Explain 0.01669
4 G-protein coupled receptor activity Function Inferred Explain 0.01404
5 neurotransmitter transport Function Inferred Explain 0.01105
6 Neuroactive ligand-receptor interaction - Homo sapiens (human) Pathway Inferred Explain 0.00967
7 G-protein coupled receptor protein signaling pathway Function Inferred Explain 0.00908
8 Membrane Component Inferred Explain 0.00877
9 membrane fraction Component Inferred Explain 0.00768
10 GPCR, rhodopsin-like superfamily Domain Inferred Explain 0.00579
11 7TM GPCR, rhodopsin-like Domain Inferred Explain 0.00573
12 Transmembrane Transport Function Inferred Explain 0.00571
13 Cell Adhesion Function Inferred Explain 0.00564
14 integral to membrane Component Known Explain 0.00524
15 Ion Transport Function Inferred Explain 0.00491
16 Protein Binding Function Inferred Explain 0.00487
17 neurotransmitter:sodium symporter activity Function Inferred Explain 0.00467
18 Sodium:neurotransmitter symporter, GABA, GAT-1 Domain Known Explain 0.00424
19 Sodium:neurotransmitter symporter, GABA, GAT-2 Domain Known Explain 0.00424
20 Sodium:neurotransmitter symporter, GABA, GAT-3 Domain Known Explain 0.00424
21 Sodium:neurotransmitter symporter, betaine Domain Known Explain 0.00424
22 Sodium:neurotransmitter symporter, noradrenaline Domain Known Explain 0.00416
23 Sodium:neurotransmitter symporter, orphan Domain Known Explain 0.00416
24 symporter activity Function Inferred Explain 0.00406
25 Sodium:neurotransmitter symporter, serotonin, N-terminal Domain Known Explain 0.00388
26 Cyclosporine Compound Inferred Explain 0.00385
27 transmembrane receptor activity Function Inferred Explain 0.00381
28 Sodium:neurotransmitter symporter, glycine, type 1 Domain Known Explain 0.00380
29 Sodium:neurotransmitter symporter, dopamine Domain Known Explain 0.00379
30 Synaptic Transmission Function Inferred Explain 0.00372
31 Sodium:neurotransmitter symporter, creatine Domain Known Explain 0.00363
32 Sodium:neurotransmitter symporter, taurine Domain Known Explain 0.00362
33 homophilic cell adhesion Function Inferred Explain 0.00357
34 Biological Transport Function Inferred Explain 0.00351
35 gamma-aminobutyric acid:sodium symporter activity Function Inferred Explain 0.00340
36 GYPB gene Gene Known Explain 0.00336
37 integral to external side of plasma membrane Component Known Explain 0.00336
38 Tyrosine-protein kinase, ephrin receptor Domain Known Explain 0.00314
39 IPR022319 Domain Known Explain 0.00314
40 GYPE gene Gene Known Explain 0.00312
41 RHAG gene Gene Known Explain 0.00312
42 RXFP3 gene Gene Known Explain 0.00310
43 CEACAM4 gene Gene Known Explain 0.00309
44 Signal Transduction Function Inferred Explain 0.00308
45 IPR022461 Domain Known Explain 0.00304
46 PODXL2 gene Gene Known Explain 0.00302
47 CD300C gene Gene Known Explain 0.00301
48 Lysosomal-associated transmembrane protein 5 Domain Known Explain 0.00299
49 Estradiol Compound Inferred Explain 0.00298
50 Immune response Function Inferred Explain 0.00297
51 IPR022318 Domain Known Explain 0.00297
52 GPR172B gene Gene Known Explain 0.00294
53 TSPAN15 gene Gene Known Explain 0.00292
54 TSPAN9 gene Gene Known Explain 0.00291
55 Benzo(a)pyrene Compound Inferred Explain 0.00290
56 LRRC32 gene Gene Known Explain 0.00288
57 SYNGR2 gene Gene Known Explain 0.00288
58 TM4SF5 gene Gene Known Explain 0.00288
59 Glycine receptor alpha Domain Known Explain 0.00288
60 KIR2DS3 gene Gene Known Explain 0.00285
61 CD200 gene Gene Known Explain 0.00284
62 CEACAM8 gene Gene Known Explain 0.00279
63 IGDCC3 gene Gene Known Explain 0.00279
64 Immunoglobulin-like fold Domain Inferred Explain 0.00278
65 Cation/acetate symporter ActP Domain Known Explain 0.00276
66 Tetrachlorodibenzodioxin Compound Inferred Explain 0.00275
67 PCDHAC1 gene Gene Known Explain 0.00273
68 PCDHB12 gene Gene Known Explain 0.00273
69 ODZ1 gene Gene Known Explain 0.00272
70 KIR2DS4 gene Gene Known Explain 0.00269
71 GPR20 gene Gene Known Explain 0.00268
72 GPR21 gene Gene Known Explain 0.00268
73 GPR22 gene Gene Known Explain 0.00268
74 GPR31 gene Gene Known Explain 0.00268
75 GPR52 gene Gene Known Explain 0.00268
76 GPR75 gene Gene Known Explain 0.00268
77 Transmembrane serine protease, TMPRSS9 Domain Known Explain 0.00268
78 PCDH11X gene Gene Known Explain 0.00267
79 Vascular endothelial growth factor receptor, VEGFR, N-terminal Domain Known Explain 0.00266
80 SLC22A14 gene Gene Known Explain 0.00265
81 TMEM8A gene Gene Known Explain 0.00265
82 Tie2 Ig-like domain 1, N-terminal Domain Known Explain 0.00264
83 PRRG2 gene Gene Known Explain 0.00264
84 GPR172A gene Gene Known Explain 0.00263
85 SYT13 gene Gene Known Explain 0.00263
86 Vascular endothelial growth factor receptor 1, VEGFR1, N-terminal Domain Known Explain 0.00263
87 Tryptophan/tyrosine transporter Domain Known Explain 0.00262
88 SLC31A2 gene Gene Known Explain 0.00262
89 Vascular endothelial growth factor receptor 3, VEGFR3, N-terminal Domain Known Explain 0.00261
90 NKG7 gene Gene Known Explain 0.00261
91 PCDHB15 gene Gene Known Explain 0.00261
92 cell surface receptor linked signaling pathway Function Inferred Explain 0.00260
93 SIGLEC9 gene Gene Known Explain 0.00259
94 RarD protein Domain Known Explain 0.00259
95 GPR42 gene Gene Known Explain 0.00258
96 TSPAN13 gene Gene Known Explain 0.00257
97 TMPRSS9 gene Gene Known Explain 0.00257
98 GPR19 gene Gene Known Explain 0.00256
99 TYROBP gene Gene Known Explain 0.00256
100 GPA33 gene Gene Known Explain 0.00252