hemoglobin biosynthetic process

Function • C1157477

Definition

The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. [GOC:jl, http://cancerweb.ncl.ac.uk/]

Synonyms

hemoglobin biosynthetic process • haemoglobin biosynthetic process • hemoglobin biosynthesis • haemoglobin biosynthesis • hemoglobin anabolism • hemoglobin formation • hemoglobin synthesis

Linked items?Related concepts, ordered by their global importance in the network.

INHBA gene    EPO gene    INHA gene    ALAS2 gene    cellular macromolecule biosynthetic process    hemoglobin metabolic process   

Related concepts

# Concept name Type Relation Support Score
1 hemoglobin metabolic process Function Known Explain 58.46355
2 cellular macromolecule biosynthetic process Function Known Explain 38.84301
3 ALAS2 gene Gene Known Explain 21.95652
4 INHA gene Gene Known Explain 19.41781
5 EPO gene Gene Known Explain 13.53812
6 INHBA gene Gene Known Explain 12.38864
7 cellular macromolecule metabolic process Function Inferred Explain 0.54773
8 hemoglobin catabolic process Function Inferred Explain 0.54092
9 Alpha-haemoglobin stabilising protein Domain Inferred Explain 0.42513
10 poly-gamma-glutamate biosynthetic process Function Inferred Explain 0.39273
11 ferredoxin biosynthetic process Function Inferred Explain 0.35061
12 AHSP gene Gene Inferred Explain 0.30200
13 cellular component macromolecule biosynthetic process Function Inferred Explain 0.20546
14 HPX gene Gene Inferred Explain 0.15819
15 Protein Metabolism Function Inferred Explain 0.13543
16 EPB42 gene Gene Inferred Explain 0.12195
17 lipoprotein biosynthetic process Function Inferred Explain 0.11715
18 ferredoxin metabolic process Function Inferred Explain 0.11192
19 macromolecule biosynthetic process Function Inferred Explain 0.09194
20 capsule poly-gamma-glutamate biosynthetic process Function Inferred Explain 0.09111
21 poly-gamma-glutamate metabolic process Function Inferred Explain 0.08641
22 erythrocyte differentiation Function Inferred Explain 0.07071
23 cellular polysaccharide biosynthetic process Function Inferred Explain 0.06355
24 inhibin A complex Component Inferred Explain 0.05041
25 negative regulation of follicle-stimulating hormone secretion Function Inferred Explain 0.04749
26 PTH gene Gene Inferred Explain 0.04561
27 positive regulation of follicle-stimulating hormone secretion Function Inferred Explain 0.04485
28 proteolysis involved in cellular protein catabolic process Function Inferred Explain 0.04066
29 cell wall macromolecule biosynthetic process Function Inferred Explain 0.03771
30 CAT gene Gene Inferred Explain 0.03577
31 capsule organization Function Inferred Explain 0.03508
32 2-Amino-3-oxoadipate Compound Inferred Explain 0.03501
33 negative regulation of macrophage differentiation Function Inferred Explain 0.03275
34 L-2-Amino-3-oxobutanoic acid Compound Inferred Explain 0.03107
35 INHBB gene Gene Inferred Explain 0.03017
36 negative regulation of B cell differentiation Function Inferred Explain 0.02941
37 negative regulation of interferon-gamma biosynthetic process Function Inferred Explain 0.02909
38 Glycoprotein Biosynthesis Pathway Function Inferred Explain 0.02717
39 regulation of follicle-stimulating hormone secretion Function Inferred Explain 0.02487
40 5-aminolevulinate synthase activity Function Inferred Explain 0.02382
41 Inhibin, alpha subunit subgroup Domain Inferred Explain 0.02171
42 Erythropoietin Domain Inferred Explain 0.02021
43 Transforming growth factor beta, conserved site Domain Inferred Explain 0.02009
44 oxygen homeostasis Function Inferred Explain 0.01981
45 Aminolevulinic Acid Compound Inferred Explain 0.01864
46 translational elongation Function Inferred Explain 0.01820
47 Transforming growth factor beta Domain Inferred Explain 0.01809
48 ALAS1 gene Gene Inferred Explain 0.01749
49 succinyl-coenzyme A Compound Inferred Explain 0.01697
50 negative regulation of phosphorylation Function Inferred Explain 0.01670
51 ACVR2A gene Gene Inferred Explain 0.01658
52 Sideroblastic anemia Disease Inferred Explain 0.01622
53 cellular biosynthetic process Function Inferred Explain 0.01613
54 inhibin beta-A binding Function Inferred Explain 0.01612
55 Inhibin, alpha subunit Domain Inferred Explain 0.01531
56 inhibin-betaglycan-ActRII complex Component Inferred Explain 0.01524
57 transferase activity, transferring nitrogenous groups Function Inferred Explain 0.01486
58 FST gene Gene Inferred Explain 0.01435
59 glycine binding Function Inferred Explain 0.01395
60 erythropoietin receptor binding activity Function Inferred Explain 0.01292
61 Erythropoietin/thrombopoeitin, conserved site Domain Inferred Explain 0.01274
62 Erythropoietin/thrombopoeitin Domain Inferred Explain 0.01260
63 Ovarian follicle development Function Inferred Explain 0.01213
64 RABGGTB gene Gene Inferred Explain 0.01111
65 capsule polysaccharide biosynthetic process Function Inferred Explain 0.01018
66 porphyrin metabolic process Function Inferred Explain 0.00985
67 Dibutyl Phthalate Compound Inferred Explain 0.00964
68 Glycine Compound Inferred Explain 0.00943
69 TGFBR3 gene Gene Inferred Explain 0.00925
70 SUCLA2 gene Gene Inferred Explain 0.00902
71 tetrapyrrole biosynthetic process Function Inferred Explain 0.00899
72 hormone activity Function Inferred Explain 0.00896
73 photoreceptor inner segment Component Inferred Explain 0.00890
74 negative regulation of cell cycle Function Inferred Explain 0.00881
75 activin A complex location Component Inferred Explain 0.00850
76 Transcription, Genetic Function Inferred Explain 0.00831
77 mesodermal cell differentiation Function Inferred Explain 0.00816
78 inhibin complex Component Inferred Explain 0.00811
79 heme biosynthetic process Function Inferred Explain 0.00784
80 Porphyrin and Chlorophyll Metabolism Pathway Function Inferred Explain 0.00773
81 male gonad development Function Inferred Explain 0.00772
82 external encapsulating structure organization Function Inferred Explain 0.00758
83 DNA biosynthesis Function Inferred Explain 0.00745
84 erythrocyte maturation Function Inferred Explain 0.00699
85 macromolecule metabolic process Function Inferred Explain 0.00697
86 hemoglobin binding Function Inferred Explain 0.00689
87 Glycine, Serine and Threonine Metabolism Pathway Function Inferred Explain 0.00683
88 cellular polysaccharide metabolic process Function Inferred Explain 0.00674
89 Inhibin, beta A subunit, N-terminal Domain Inferred Explain 0.00654
90 follistatin binding Function Inferred Explain 0.00634
91 Acetyl Coenzyme A Compound Inferred Explain 0.00632
92 positive regulation of ovulation Function Inferred Explain 0.00626
93 response to hypoxia Function Inferred Explain 0.00606
94 coenzyme binding Function Inferred Explain 0.00573
95 Amitrole Compound Inferred Explain 0.00567
96 photoreceptor outer segment Component Inferred Explain 0.00557
97 Transforming growth factor beta (TGFb), N-terminal Domain Inferred Explain 0.00557
98 INHBC gene Gene Inferred Explain 0.00554
99 Transforming growth factor-beta-related Domain Inferred Explain 0.00537
100 Th-1165a Compound Inferred Explain 0.00536