Endotoxemia

Disease • C0376618

Definition

A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Synonyms

Endotoxemia • Endotoxemias • Endotoxemia [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

Indomethacin    Ibuprofen    Lipopolysaccharides    ALOX5 gene    zileuton    phenylmethylpyrazolone    lipopolysaccharide, Escherichia coli 0111 B4    dang-gui    lipopolysaccharide, E. coli 026-B6    Bacteremia    Septic Toxemia    endotoxin, Escherichia coli    angelicae sinensis extract   

Related concepts

# Concept name Type Relation Support Score
1 angelicae sinensis extract Compound Known Explain 25.42042
2 endotoxin, Escherichia coli Compound Known Explain 23.67141
3 Septic Toxemia Disease Known Explain 19.94048
4 lipopolysaccharide, E. coli 026-B6 Compound Known Explain 19.74390
5 lipopolysaccharide, Escherichia coli 0111 B4 Compound Known Explain 14.59592
6 dang-gui Compound Known Explain 13.21102
7 Bacteremia Disease Known Explain 12.30315
8 phenylmethylpyrazolone Compound Known Explain 8.94275
9 Pyemia Disease Inferred Explain 4.80299
10 zileuton Compound Known Explain 4.20545
11 Endotoxic shock Disease Inferred Explain 2.91784
12 ALOX5 gene Gene Known Explain 2.71981
13 Pre-Eclampsia Disease Inferred Explain 1.80094
14 Fever Disease Inferred Explain 1.74442
15 Lipopolysaccharides Compound Known Explain 1.59693
16 Ibuprofen Compound Known Explain 1.55132
17 Infection Disease Inferred Explain 0.69142
18 Indomethacin Compound Known Explain 0.64847
19 Systemic infection Disease Inferred Explain 0.27291
20 Hemorrhagic Septicemia Disease Inferred Explain 0.25643
21 Cromoglycate Compound Inferred Explain 0.13261
22 Berry Aneurysm Disease Inferred Explain 0.12447
23 NFKBIA gene Gene Inferred Explain 0.10487
24 Diphenhydramine Hydrochloride Compound Inferred Explain 0.10030
25 Bacterial Infections Disease Inferred Explain 0.09177
26 NFKB1 gene Gene Inferred Explain 0.08607
27 Triprolidine Compound Inferred Explain 0.07205
28 Mangifera indica extract Compound Inferred Explain 0.07166
29 Left Ventricular Hypertrophy Disease Inferred Explain 0.07102
30 RELA gene Gene Inferred Explain 0.06703
31 Ischemia Disease Inferred Explain 0.06651
32 Reperfusion Injury Other Inferred Explain 0.05914
33 Cerebral hemisphere hemorrhage Disease Inferred Explain 0.05140
34 Gynecomastia Disease Inferred Explain 0.05099
35 PTGS2 gene Gene Inferred Explain 0.04955
36 CCL3 gene Gene Inferred Explain 0.04846
37 SELE gene Gene Inferred Explain 0.04292
38 SPP1 gene Gene Inferred Explain 0.04160
39 Systemic Inflammatory Response Syndrome Disease Inferred Explain 0.03945
40 TIRAP gene Gene Inferred Explain 0.03908
41 F3 gene Gene Inferred Explain 0.03835
42 mangiferin Compound Inferred Explain 0.03702
43 C5AR1 gene Gene Inferred Explain 0.03563
44 Hot flushes Disease Inferred Explain 0.03451
45 Drug toxicity Other Inferred Explain 0.03224
46 KWD-2019 Compound Inferred Explain 0.03052
47 Septic Shock Disease Inferred Explain 0.02991
48 Middle Cerebral Artery Syndrome Disease Inferred Explain 0.02867
49 TNF gene Gene Inferred Explain 0.02837
50 Fatty Liver Disease Inferred Explain 0.02834
51 Decompression Sickness Disease Inferred Explain 0.02824
52 anaphylaxis Disease Inferred Explain 0.02820
53 Metabolic Diseases Disease Inferred Explain 0.02638
54 Fractures, Closed Other Inferred Explain 0.02570
55 Pancreatitis Disease Inferred Explain 0.02514
56 IL6 gene Gene Inferred Explain 0.02512
57 Myocardial Reperfusion Injury Disease Inferred Explain 0.02415
58 Cerebral Edema Disease Inferred Explain 0.02297
59 Pasteurella Infections Disease Inferred Explain 0.02225
60 Asthma, Exercise-Induced Disease Inferred Explain 0.01955
61 NGF gene Gene Inferred Explain 0.01949
62 Acute Lung Injury Other Inferred Explain 0.01920
63 Sleep Apnea, Obstructive Disease Inferred Explain 0.01870
64 Fungemia Disease Inferred Explain 0.01779
65 Edema Disease Inferred Explain 0.01714
66 Parasitemia Disease Inferred Explain 0.01681
67 Sinusitis Disease Inferred Explain 0.01648
68 Nasal Polyps Other Inferred Explain 0.01620
69 Viremia Disease Inferred Explain 0.01588
70 Pulmonary Edema Disease Inferred Explain 0.01581
71 Rheumatoid Arthritis Disease Inferred Explain 0.01554
72 Glycolipids Compound Inferred Explain 0.01430
73 Isoflurane Compound Inferred Explain 0.01297
74 Spinal Cord Injuries Other Inferred Explain 0.01281
75 IL1B gene Gene Inferred Explain 0.01150
76 Myeloid Leukemia, Chronic Disease Inferred Explain 0.01089
77 Acne Vulgaris Disease Inferred Explain 0.01069
78 tetracycline CMT-3 Compound Inferred Explain 0.01068
79 Inflammation Disease Inferred Explain 0.01056
80 Ayerza Syndrome Disease Inferred Explain 0.01050
81 Peritonitis Disease Inferred Explain 0.01049
82 Bronchial Hyperreactivity Disease Inferred Explain 0.01024
83 Kidney Diseases Disease Inferred Explain 0.01019
84 NOS3 gene Gene Inferred Explain 0.00979
85 Pruritus Disease Inferred Explain 0.00967
86 TFF1 gene Gene Inferred Explain 0.00934
87 VEGFA gene Gene Inferred Explain 0.00928
88 KLK3 gene Gene Inferred Explain 0.00908
89 montelukast Compound Inferred Explain 0.00897
90 Inflammatory Bowel Diseases Disease Inferred Explain 0.00887
91 IL8 gene Gene Inferred Explain 0.00882
92 Pain Disease Inferred Explain 0.00834
93 zafirlukast Compound Inferred Explain 0.00828
94 Rhinitis Disease Inferred Explain 0.00801
95 Eosinophilia Disease Inferred Explain 0.00791
96 HIF1A gene Gene Inferred Explain 0.00774
97 8-epi-prostaglandin F2alpha Compound Inferred Explain 0.00749
98 Asthma Disease Inferred Explain 0.00723
99 Hepatomegaly Disease Inferred Explain 0.00684
100 carbabenzpyride Compound Inferred Explain 0.00649