|
aloe emodin
|
Compound • C0282164
Synonyms
aloe emodin • 1,8-dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
|
|
Inflammation
NAT1 gene
|
Related concepts
|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
NAT1 gene
|
Gene
|
Known
|
Explain
|
90.85649
|
|
2
|
Inflammation
|
Disease
|
Known
|
Explain
|
60.62686
|
|
3
|
NAT2 gene
|
Gene
|
Inferred
|
Explain
|
0.68242
|
|
4
|
4-Aminobenzoic Acid
|
Compound
|
Inferred
|
Explain
|
0.11252
|
|
5
|
4-bromoaniline
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
6
|
4-iodoaniline
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
7
|
Aniline
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
8
|
KEGG:cpd:C02558
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
9
|
Acetylhydrazine
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
10
|
N-Acetylisoniazid
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
11
|
5-Acetylamino-6-formylamino-3-methyluracil
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
12
|
2,4-Diamino-6-nitrotoluene
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
13
|
4-Acetamido-2-amino-6-nitrotoluene
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
14
|
N,N'-Diacetylhydrazine
|
Compound
|
Inferred
|
Explain
|
0.08859
|
|
15
|
Procainamide
|
Compound
|
Inferred
|
Explain
|
0.08588
|
|
16
|
Carotene
|
Compound
|
Inferred
|
Explain
|
0.08224
|
|
17
|
2-aminofluorene
|
Compound
|
Inferred
|
Explain
|
0.08224
|
|
18
|
cafestol palmitate
|
Compound
|
Inferred
|
Explain
|
0.07751
|
|
19
|
2-tolidine
|
Compound
|
Inferred
|
Explain
|
0.07727
|
|
20
|
dihydrofolate
|
Compound
|
Inferred
|
Explain
|
0.07639
|
|
21
|
4-chloroaniline
|
Compound
|
Inferred
|
Explain
|
0.07624
|
|
22
|
1,6-hexamethylene diisocyanate
|
Compound
|
Inferred
|
Explain
|
0.07253
|
|
23
|
arylamine N-acetyltransferase activity
|
Function
|
Inferred
|
Explain
|
0.07015
|
|
24
|
cafestol
|
Compound
|
Inferred
|
Explain
|
0.06729
|
|
25
|
kahweol
|
Compound
|
Inferred
|
Explain
|
0.06729
|
|
26
|
5-Aminosalicylate
|
Compound
|
Inferred
|
Explain
|
0.06681
|
|
27
|
4,4'-diphenylmethane diisocyanate
|
Compound
|
Inferred
|
Explain
|
0.06518
|
|
28
|
Peroxynitrite
|
Compound
|
Inferred
|
Explain
|
0.05998
|
|
29
|
2-anisidine
|
Compound
|
Inferred
|
Explain
|
0.05871
|
|
30
|
nitrobenzanthrone
|
Compound
|
Inferred
|
Explain
|
0.05865
|
|
31
|
Caffeine metabolism - Homo sapiens (human)
|
Pathway
|
Inferred
|
Explain
|
0.05515
|
|
32
|
DP 178
|
Compound
|
Inferred
|
Explain
|
0.05318
|
|
33
|
CV 664
|
Compound
|
Inferred
|
Explain
|
0.05211
|
|
34
|
Hair Dyes
|
Compound
|
Inferred
|
Explain
|
0.05030
|
|
35
|
benzidine
|
Compound
|
Inferred
|
Explain
|
0.04987
|
|
36
|
9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole
|
Compound
|
Inferred
|
Explain
|
0.04955
|
|
37
|
2-amino-3-methyl-9H-pyrido(2,3-b)indole
|
Compound
|
Inferred
|
Explain
|
0.04519
|
|
38
|
Aniline Compounds
|
Compound
|
Inferred
|
Explain
|
0.04212
|
|
39
|
isoniazid
|
Compound
|
Inferred
|
Explain
|
0.03548
|
|
40
|
nitrofen
|
Compound
|
Inferred
|
Explain
|
0.03483
|
|
41
|
1,7-Dimethylxanthine
|
Compound
|
Inferred
|
Explain
|
0.03445
|
|
42
|
TZI 41127
|
Compound
|
Inferred
|
Explain
|
0.03351
|
|
43
|
cacospongionolide B
|
Compound
|
Inferred
|
Explain
|
0.03311
|
|
44
|
petrosaspongiolide m
|
Compound
|
Inferred
|
Explain
|
0.03268
|
|
45
|
bolinaquinone
|
Compound
|
Inferred
|
Explain
|
0.03207
|
|
46
|
flunisolide
|
Compound
|
Inferred
|
Explain
|
0.03139
|
|
47
|
Foreign-Body Reaction
|
Disease
|
Inferred
|
Explain
|
0.03077
|
|
48
|
NAA10 gene
|
Gene
|
Inferred
|
Explain
|
0.03020
|
|
49
|
4-biphenylamine
|
Compound
|
Inferred
|
Explain
|
0.03018
|
|
50
|
Flexidol
|
Compound
|
Inferred
|
Explain
|
0.02952
|
|
51
|
Mecholyl
|
Compound
|
Inferred
|
Explain
|
0.02934
|
|
52
|
2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran
|
Compound
|
Inferred
|
Explain
|
0.02852
|
|
53
|
MDL 28170
|
Compound
|
Inferred
|
Explain
|
0.02801
|
|
54
|
2-Acetylaminofluorene
|
Compound
|
Inferred
|
Explain
|
0.02791
|
|
55
|
acetyltransferase activity
|
Function
|
Inferred
|
Explain
|
0.02764
|
|
56
|
1-(4-(benzothiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid
|
Compound
|
Inferred
|
Explain
|
0.02745
|
|
57
|
tcdA protein, Clostridium difficile
|
Compound
|
Inferred
|
Explain
|
0.02724
|
|
58
|
Amines
|
Compound
|
Inferred
|
Explain
|
0.02650
|
|
59
|
Quartz
|
Compound
|
Inferred
|
Explain
|
0.02597
|
|
60
|
baicalein
|
Compound
|
Inferred
|
Explain
|
0.02484
|
|
61
|
Systemic Inflammatory Response Syndrome
|
Disease
|
Inferred
|
Explain
|
0.02410
|
|
62
|
Fibrates
|
Compound
|
Inferred
|
Explain
|
0.02295
|
|
63
|
2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid
|
Compound
|
Inferred
|
Explain
|
0.02278
|
|
64
|
Freund's Adjuvant
|
Compound
|
Inferred
|
Explain
|
0.02261
|
|
65
|
4-phenylenediamine
|
Compound
|
Inferred
|
Explain
|
0.02241
|
|
66
|
Edema
|
Disease
|
Inferred
|
Explain
|
0.02226
|
|
67
|
Carrageenan
|
Compound
|
Inferred
|
Explain
|
0.02125
|
|
68
|
CYP1A2 gene
|
Gene
|
Inferred
|
Explain
|
0.02100
|
|
69
|
honokiol
|
Compound
|
Inferred
|
Explain
|
0.02053
|
|
70
|
Tolmetin
|
Compound
|
Inferred
|
Explain
|
0.01833
|
|
71
|
ursolic acid
|
Compound
|
Inferred
|
Explain
|
0.01831
|
|
72
|
Toluene 2,4-Diisocyanate
|
Compound
|
Inferred
|
Explain
|
0.01790
|
|
73
|
Polycyclic Hydrocarbons, Aromatic
|
Compound
|
Inferred
|
Explain
|
0.01766
|
|
74
|
Desmodium gangeticum extract
|
Compound
|
Inferred
|
Explain
|
0.01765
|
|
75
|
Drug metabolism - other enzymes - Homo sapiens (human)
|
|
Inferred
|
Explain
|
0.01763
|
|
76
|
ethylisopropylamiloride
|
Compound
|
Inferred
|
Explain
|
0.01696
|
|
77
|
Iodine
|
Compound
|
Inferred
|
Explain
|
0.01690
|
|
78
|
perfluorooctanoic acid
|
Compound
|
Inferred
|
Explain
|
0.01680
|
|
79
|
Neurogenic Inflammation
|
Other
|
Inferred
|
Explain
|
0.01667
|
|
80
|
Procaine
|
Compound
|
Inferred
|
Explain
|
0.01652
|
|
81
|
L 660,711
|
Compound
|
Inferred
|
Explain
|
0.01603
|
|
82
|
Crotalid Venoms
|
Compound
|
Inferred
|
Explain
|
0.01574
|
|
83
|
Oleanolic Acid
|
Compound
|
Inferred
|
Explain
|
0.01531
|
|
84
|
Bupivacaine
|
Compound
|
Inferred
|
Explain
|
0.01511
|
|
85
|
Roxithromycin
|
Compound
|
Inferred
|
Explain
|
0.01488
|
|
86
|
Mangifera indica extract
|
Compound
|
Inferred
|
Explain
|
0.01470
|
|
87
|
Heme
|
Compound
|
Inferred
|
Explain
|
0.01422
|
|
88
|
Suppurative inflammation
|
Disease
|
Inferred
|
Explain
|
0.01421
|
|
89
|
Acetyl Coenzyme A
|
Compound
|
Inferred
|
Explain
|
0.01400
|
|
90
|
Metals
|
Compound
|
Inferred
|
Explain
|
0.01332
|
|
91
|
ONO-RS 411
|
Compound
|
Inferred
|
Explain
|
0.01327
|
|
92
|
LTB4R gene
|
Gene
|
Inferred
|
Explain
|
0.01295
|
|
93
|
Silver
|
Compound
|
Inferred
|
Explain
|
0.01282
|
|
94
|
PTGER4 gene
|
Gene
|
Inferred
|
Explain
|
0.01269
|
|
95
|
CYP1A1 gene
|
Gene
|
Inferred
|
Explain
|
0.01266
|
|
96
|
CRHR2 gene
|
Gene
|
Inferred
|
Explain
|
0.01260
|
|
97
|
nimesulide
|
Compound
|
Inferred
|
Explain
|
0.01251
|
|
98
|
Anafranil
|
Compound
|
Inferred
|
Explain
|
0.01247
|
|
99
|
UCN3 gene
|
Gene
|
Inferred
|
Explain
|
0.01242
|
|
100
|
Fenoprofen
|
Compound
|
Inferred
|
Explain
|
0.01232
|
|