|
piperine
Related concepts
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
1
|
UGDH gene
|
Gene
|
Known
|
Explain
|
3.00734
|
2
|
REL gene
|
Gene
|
Known
|
Explain
|
2.69720
|
3
|
ATF2 gene
|
Gene
|
Known
|
Explain
|
2.34389
|
4
|
CSF2 gene
|
Gene
|
Known
|
Explain
|
1.48778
|
5
|
MMP2 gene
|
Gene
|
Known
|
Explain
|
1.16298
|
6
|
CREB1 gene
|
Gene
|
Known
|
Explain
|
1.05815
|
7
|
MMP9 gene
|
Gene
|
Known
|
Explain
|
0.94637
|
8
|
NFKB1 gene
|
Gene
|
Known
|
Explain
|
0.56558
|
9
|
FOS gene
|
Gene
|
Known
|
Explain
|
0.54713
|
10
|
IL1B gene
|
Gene
|
Known
|
Explain
|
0.49216
|
11
|
IL6 gene
|
Gene
|
Known
|
Explain
|
0.44011
|
12
|
RELA gene
|
Gene
|
Known
|
Explain
|
0.43211
|
13
|
CYP1A1 gene
|
Gene
|
Known
|
Explain
|
0.36480
|
14
|
TNF gene
|
Gene
|
Known
|
Explain
|
0.32657
|
15
|
IL8 gene
|
Gene
|
Inferred
|
Explain
|
0.00503
|
16
|
Nucleotide sugar dehydrogenase
|
Domain
|
Inferred
|
Explain
|
0.00394
|
17
|
Protein Binding
|
Function
|
Inferred
|
Explain
|
0.00319
|
18
|
UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding domain
|
Domain
|
Inferred
|
Explain
|
0.00312
|
19
|
Cell Nucleus
|
Component
|
Inferred
|
Explain
|
0.00260
|
20
|
UDP-glucose/GDP-mannose dehydrogenase, dimerisation
|
Domain
|
Inferred
|
Explain
|
0.00259
|
21
|
UDP-glucose/GDP-mannose dehydrogenase, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.00258
|
22
|
MAPK1 gene
|
Gene
|
Inferred
|
Explain
|
0.00247
|
23
|
UDP-glucose 6-dehydrogenase activity
|
Function
|
Inferred
|
Explain
|
0.00242
|
24
|
fucoidan
|
Compound
|
Inferred
|
Explain
|
0.00233
|
25
|
PTGS2 gene
|
Gene
|
Inferred
|
Explain
|
0.00232
|
26
|
CYP1A2 gene
|
Gene
|
Inferred
|
Explain
|
0.00222
|
27
|
UDP-glucose/GDP-mannose dehydrogenase, N-terminal
|
Domain
|
Inferred
|
Explain
|
0.00219
|
28
|
NFKBIA gene
|
Gene
|
Inferred
|
Explain
|
0.00210
|
29
|
MAPK3 gene
|
Gene
|
Inferred
|
Explain
|
0.00208
|
30
|
IPR021157
|
Domain
|
Inferred
|
Explain
|
0.00208
|
31
|
Cyclosporine
|
Compound
|
Inferred
|
Explain
|
0.00205
|
32
|
Tetrachlorodibenzodioxin
|
Compound
|
Inferred
|
Explain
|
0.00189
|
33
|
JUN gene
|
Gene
|
Inferred
|
Explain
|
0.00183
|
34
|
CYP1B1 gene
|
Gene
|
Inferred
|
Explain
|
0.00182
|
35
|
arsenic trioxide
|
Compound
|
Inferred
|
Explain
|
0.00180
|
36
|
6-phosphogluconate dehydrogenase, C-terminal-like
|
Domain
|
Inferred
|
Explain
|
0.00178
|
37
|
Cytoplasm
|
Component
|
Inferred
|
Explain
|
0.00177
|
38
|
Benzo(a)pyrene
|
Compound
|
Inferred
|
Explain
|
0.00176
|
39
|
Estradiol
|
Compound
|
Inferred
|
Explain
|
0.00174
|
40
|
scoparone
|
Compound
|
Inferred
|
Explain
|
0.00171
|
41
|
fly ash
|
Compound
|
Inferred
|
Explain
|
0.00167
|
42
|
CCL2 gene
|
Gene
|
Inferred
|
Explain
|
0.00167
|
43
|
Anisomycin
|
Compound
|
Inferred
|
Explain
|
0.00165
|
44
|
SB 202190
|
Compound
|
Inferred
|
Explain
|
0.00165
|
45
|
Tretinoin
|
Compound
|
Inferred
|
Explain
|
0.00164
|
46
|
PD 98059
|
Compound
|
Inferred
|
Explain
|
0.00158
|
47
|
UDP-glucuronate biosynthetic process
|
Function
|
Inferred
|
Explain
|
0.00158
|
48
|
MAPK8 gene
|
Gene
|
Inferred
|
Explain
|
0.00156
|
49
|
Tetradecanoylphorbol Acetate
|
Compound
|
Inferred
|
Explain
|
0.00156
|
50
|
CYP3A4 gene
|
Gene
|
Inferred
|
Explain
|
0.00153
|
51
|
SB 203580
|
Compound
|
Inferred
|
Explain
|
0.00144
|
52
|
Acrolein
|
Compound
|
Inferred
|
Explain
|
0.00142
|
53
|
2,2',4,6,6'-pentachlorobiphenyl
|
Compound
|
Inferred
|
Explain
|
0.00142
|
54
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
|
Compound
|
Inferred
|
Explain
|
0.00142
|
55
|
Aluminum Oxide
|
Compound
|
Inferred
|
Explain
|
0.00142
|
56
|
Fluorouracil
|
Compound
|
Inferred
|
Explain
|
0.00140
|
57
|
1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene
|
Compound
|
Inferred
|
Explain
|
0.00139
|
58
|
Acetaldehyde
|
Compound
|
Inferred
|
Explain
|
0.00138
|
59
|
Acetylcysteine
|
Compound
|
Inferred
|
Explain
|
0.00138
|
60
|
TP53 gene
|
Gene
|
Inferred
|
Explain
|
0.00136
|
61
|
sodium arsenite
|
Compound
|
Inferred
|
Explain
|
0.00136
|
62
|
Eugenol
|
Compound
|
Inferred
|
Explain
|
0.00135
|
63
|
Quercetin
|
Compound
|
Inferred
|
Explain
|
0.00135
|
64
|
Luteolin
|
Compound
|
Inferred
|
Explain
|
0.00134
|
65
|
CASP3 gene
|
Gene
|
Inferred
|
Explain
|
0.00131
|
66
|
Genistein
|
Compound
|
Inferred
|
Explain
|
0.00131
|
67
|
Toluene 2,4-Diisocyanate
|
Compound
|
Inferred
|
Explain
|
0.00126
|
68
|
Doxorubicin
|
Compound
|
Inferred
|
Explain
|
0.00126
|
69
|
hydroquinone
|
Compound
|
Inferred
|
Explain
|
0.00124
|
70
|
Disulfiram
|
Compound
|
Inferred
|
Explain
|
0.00123
|
71
|
NF-kappa-B/Rel/dorsal
|
Domain
|
Inferred
|
Explain
|
0.00123
|
72
|
2,2-bis(4-glycidyloxyphenyl)propane
|
Compound
|
Inferred
|
Explain
|
0.00123
|
73
|
AHR gene
|
Gene
|
Inferred
|
Explain
|
0.00122
|
74
|
resveratrol
|
Compound
|
Inferred
|
Explain
|
0.00121
|
75
|
fexofenadine
|
Compound
|
Inferred
|
Explain
|
0.00120
|
76
|
Metal Ion Binding
|
Function
|
Inferred
|
Explain
|
0.00120
|
77
|
bZIP transcription factor, bZIP-1
|
Domain
|
Inferred
|
Explain
|
0.00118
|
78
|
Ritonavir
|
Compound
|
Inferred
|
Explain
|
0.00118
|
79
|
Cytoplasmic matrix
|
Component
|
Inferred
|
Explain
|
0.00116
|
80
|
tyrphostin AG 1478
|
Compound
|
Inferred
|
Explain
|
0.00115
|
81
|
anthra(1,9-cd)pyrazol-6(2H)-one
|
Compound
|
Inferred
|
Explain
|
0.00114
|
82
|
ethyl acetate
|
Compound
|
Inferred
|
Explain
|
0.00114
|
83
|
Uridine Diphosphate Glucose
|
Compound
|
Inferred
|
Explain
|
0.00113
|
84
|
toll-like receptor 3 signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00113
|
85
|
MyD88-independent toll-like receptor signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00113
|
86
|
Cisplatin
|
Compound
|
Inferred
|
Explain
|
0.00111
|
87
|
extracellular region
|
Component
|
Inferred
|
Explain
|
0.00110
|
88
|
CREBBP gene
|
Gene
|
Inferred
|
Explain
|
0.00109
|
89
|
daidzein
|
Compound
|
Inferred
|
Explain
|
0.00109
|
90
|
Vehicle Emissions
|
Compound
|
Inferred
|
Explain
|
0.00109
|
91
|
Rel homology
|
Domain
|
Inferred
|
Explain
|
0.00108
|
92
|
toll-like receptor 1 signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00108
|
93
|
toll-like receptor 2 signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00108
|
94
|
tripterine
|
Compound
|
Inferred
|
Explain
|
0.00108
|
95
|
toll-like receptor signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00106
|
96
|
IFNG gene
|
Gene
|
Inferred
|
Explain
|
0.00106
|
97
|
MyD88-dependent toll-like receptor signaling pathway
|
Function
|
Inferred
|
Explain
|
0.00106
|
98
|
BCL2 gene
|
Gene
|
Inferred
|
Explain
|
0.00105
|
99
|
epigallocatechin gallate
|
Compound
|
Inferred
|
Explain
|
0.00105
|
100
|
sodium 2-(4-((1-((2-((3,3,3-trifluoro-1-isopropyl-2-oxopropyl)aminocarbonyl)pyrrolidin-1-yl)carbonyl)-2-methylpropyl)aminocarbonyl)benzoylamino)acetate
|
Compound
|
Inferred
|
Explain
|
0.00105
|
|