5-(N-methyl-N-isobutyl)amiloride

Compound • C0049022

Synonyms

5-(N-methyl-N-isobutyl)amiloride • 5-NMNIA • methylisobutylamiloride

Linked items?Related concepts, ordered by their global importance in the network.

RELA gene    NFKB1 gene    IL8 gene    IL1B gene    CCL2 gene   

Related concepts

# Concept name Type Relation Support Score
1 CCL2 gene Gene Known Explain 5.04452
2 NFKB1 gene Gene Known Explain 4.02772
3 IL1B gene Gene Known Explain 3.48028
4 IL8 gene Gene Known Explain 3.33807
5 RELA gene Gene Known Explain 3.03966
6 TNF gene Gene Inferred Explain 0.01191
7 IL6 gene Gene Inferred Explain 0.00581
8 Harmaline Compound Inferred Explain 0.00574
9 diphenyliodonium Compound Inferred Explain 0.00566
10 scoparone Compound Inferred Explain 0.00513
11 ethylisopropylamiloride Compound Inferred Explain 0.00512
12 1,3-dimethylthiourea Compound Inferred Explain 0.00497
13 Clonidine Compound Inferred Explain 0.00478
14 NFKBIA gene Gene Inferred Explain 0.00458
15 lipopolysaccharide, E coli O55-B5 Compound Inferred Explain 0.00453
16 BAY 11-7082 Compound Inferred Explain 0.00416
17 sodium 2-(4-((1-((2-((3,3,3-trifluoro-1-isopropyl-2-oxopropyl)aminocarbonyl)pyrrolidin-1-yl)carbonyl)-2-methylpropyl)aminocarbonyl)benzoylamino)acetate Compound Inferred Explain 0.00358
18 Cimetidine Compound Inferred Explain 0.00349
19 PTGS2 gene Gene Inferred Explain 0.00348
20 diphenyleneiodonium Compound Inferred Explain 0.00340
21 Tosylphenylalanyl Chloromethyl Ketone Compound Inferred Explain 0.00320
22 Methylmethacrylate Compound Inferred Explain 0.00288
23 Protein Binding Function Inferred Explain 0.00284
24 Tosyllysine Chloromethyl Ketone Compound Inferred Explain 0.00275
25 CCL5 gene Gene Inferred Explain 0.00262
26 15-deoxy-delta(12,14)-prostaglandin J2 Compound Inferred Explain 0.00259
27 Arequin Compound Inferred Explain 0.00251
28 n-dodecane Compound Inferred Explain 0.00243
29 undecane Compound Inferred Explain 0.00243
30 tridecane Compound Inferred Explain 0.00243
31 KEGG:hsa04621 Pathway Inferred Explain 0.00243
32 Shiga Toxin Compound Inferred Explain 0.00235
33 Hydroxychloroquine Compound Inferred Explain 0.00232
34 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone Compound Inferred Explain 0.00231
35 Dicumarol Compound Inferred Explain 0.00231
36 MAPK1 gene Gene Inferred Explain 0.00228
37 Cyclopentane Compound Inferred Explain 0.00226
38 MAPK3 gene Gene Inferred Explain 0.00226
39 nonane Compound Inferred Explain 0.00225
40 N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide Compound Inferred Explain 0.00223
41 tin protoporphyrin IX Compound Inferred Explain 0.00221
42 gastrin 17 Compound Inferred Explain 0.00218
43 Caffeic Acid Phenethyl Ester Compound Inferred Explain 0.00216
44 3-xylene Compound Inferred Explain 0.00213
45 Amiloride Compound Inferred Explain 0.00213
46 2,2-bis(4-glycidyloxyphenyl)propane Compound Inferred Explain 0.00211
47 CSF2 gene Gene Inferred Explain 0.00211
48 Neutrophil chemotaxis Function Inferred Explain 0.00210
49 pyrrolidine dithiocarbamic acid Compound Inferred Explain 0.00210
50 1-bromopropane Compound Inferred Explain 0.00208
51 calphostin C Compound Inferred Explain 0.00208
52 15-deoxyprostaglandin J2 Compound Inferred Explain 0.00203
53 bafilomycin A1 Compound Inferred Explain 0.00201
54 ICAM1 gene Gene Inferred Explain 0.00199
55 prolinedithiocarbamate Compound Inferred Explain 0.00198
56 fluticasone Compound Inferred Explain 0.00197
57 NS 398 Compound Inferred Explain 0.00197
58 Ionomycin Compound Inferred Explain 0.00191
59 IFNG gene Gene Inferred Explain 0.00191
60 Cell Nucleus Component Inferred Explain 0.00189
61 MMP9 gene Gene Inferred Explain 0.00186
62 Lipopolysaccharides Compound Inferred Explain 0.00182
63 Cytoplasm Component Inferred Explain 0.00182
64 Zymosan Compound Inferred Explain 0.00182
65 CCL3 gene Gene Inferred Explain 0.00181
66 Acetaldehyde Compound Inferred Explain 0.00181
67 SB 202190 Compound Inferred Explain 0.00180
68 Berberine Compound Inferred Explain 0.00178
69 lipopeptidophosphoglycan Compound Inferred Explain 0.00178
70 FOS gene Gene Inferred Explain 0.00174
71 KEGG:hsa05142 Pathway Inferred Explain 0.00173
72 chlorobenzene Compound Inferred Explain 0.00171
73 piperine Compound Inferred Explain 0.00170
74 Neurotensin Compound Inferred Explain 0.00168
75 beta-penta-O-galloyl-glucose Compound Inferred Explain 0.00165
76 PD 98059 Compound Inferred Explain 0.00165
77 Inflammatory Response Disease Inferred Explain 0.00164
78 CASP3 gene Gene Inferred Explain 0.00163
79 Simvastatin Compound Inferred Explain 0.00163
80 Gliotoxin Compound Inferred Explain 0.00161
81 Cyclosporine Compound Inferred Explain 0.00161
82 Pertussis Toxin Compound Inferred Explain 0.00160
83 Sodium Salicylate Compound Inferred Explain 0.00160
84 Estradiol Compound Inferred Explain 0.00160
85 Benzo(a)pyrene Compound Inferred Explain 0.00159
86 Chloroform Compound Inferred Explain 0.00158
87 Ammonium Chloride Compound Inferred Explain 0.00158
88 CYP1A1 gene Gene Inferred Explain 0.00157
89 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Compound Inferred Explain 0.00155
90 moxifloxacin Compound Inferred Explain 0.00154
91 lopinavir Compound Inferred Explain 0.00153
92 IL10 gene Gene Inferred Explain 0.00152
93 hyperforin Compound Inferred Explain 0.00152
94 Tetrachlorodibenzodioxin Compound Inferred Explain 0.00151
95 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt Compound Inferred Explain 0.00150
96 deoxynivalenol Compound Inferred Explain 0.00149
97 1-nitropyrene Compound Inferred Explain 0.00148
98 SB 203580 Compound Inferred Explain 0.00147
99 BAY 11-7085 Compound Inferred Explain 0.00146
100 Sulfasalazine Compound Inferred Explain 0.00146