|
5-(N-methyl-N-isobutyl)amiloride
Related concepts
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
1
|
CCL2 gene
|
Gene
|
Known
|
Explain
|
5.04452
|
2
|
NFKB1 gene
|
Gene
|
Known
|
Explain
|
4.02772
|
3
|
IL1B gene
|
Gene
|
Known
|
Explain
|
3.48028
|
4
|
IL8 gene
|
Gene
|
Known
|
Explain
|
3.33807
|
5
|
RELA gene
|
Gene
|
Known
|
Explain
|
3.03966
|
6
|
TNF gene
|
Gene
|
Inferred
|
Explain
|
0.01191
|
7
|
IL6 gene
|
Gene
|
Inferred
|
Explain
|
0.00581
|
8
|
Harmaline
|
Compound
|
Inferred
|
Explain
|
0.00574
|
9
|
diphenyliodonium
|
Compound
|
Inferred
|
Explain
|
0.00566
|
10
|
scoparone
|
Compound
|
Inferred
|
Explain
|
0.00513
|
11
|
ethylisopropylamiloride
|
Compound
|
Inferred
|
Explain
|
0.00512
|
12
|
1,3-dimethylthiourea
|
Compound
|
Inferred
|
Explain
|
0.00497
|
13
|
Clonidine
|
Compound
|
Inferred
|
Explain
|
0.00478
|
14
|
NFKBIA gene
|
Gene
|
Inferred
|
Explain
|
0.00458
|
15
|
lipopolysaccharide, E coli O55-B5
|
Compound
|
Inferred
|
Explain
|
0.00453
|
16
|
BAY 11-7082
|
Compound
|
Inferred
|
Explain
|
0.00416
|
17
|
sodium 2-(4-((1-((2-((3,3,3-trifluoro-1-isopropyl-2-oxopropyl)aminocarbonyl)pyrrolidin-1-yl)carbonyl)-2-methylpropyl)aminocarbonyl)benzoylamino)acetate
|
Compound
|
Inferred
|
Explain
|
0.00358
|
18
|
Cimetidine
|
Compound
|
Inferred
|
Explain
|
0.00349
|
19
|
PTGS2 gene
|
Gene
|
Inferred
|
Explain
|
0.00348
|
20
|
diphenyleneiodonium
|
Compound
|
Inferred
|
Explain
|
0.00340
|
21
|
Tosylphenylalanyl Chloromethyl Ketone
|
Compound
|
Inferred
|
Explain
|
0.00320
|
22
|
Methylmethacrylate
|
Compound
|
Inferred
|
Explain
|
0.00288
|
23
|
Protein Binding
|
Function
|
Inferred
|
Explain
|
0.00284
|
24
|
Tosyllysine Chloromethyl Ketone
|
Compound
|
Inferred
|
Explain
|
0.00275
|
25
|
CCL5 gene
|
Gene
|
Inferred
|
Explain
|
0.00262
|
26
|
15-deoxy-delta(12,14)-prostaglandin J2
|
Compound
|
Inferred
|
Explain
|
0.00259
|
27
|
Arequin
|
Compound
|
Inferred
|
Explain
|
0.00251
|
28
|
n-dodecane
|
Compound
|
Inferred
|
Explain
|
0.00243
|
29
|
undecane
|
Compound
|
Inferred
|
Explain
|
0.00243
|
30
|
tridecane
|
Compound
|
Inferred
|
Explain
|
0.00243
|
31
|
KEGG:hsa04621
|
Pathway
|
Inferred
|
Explain
|
0.00243
|
32
|
Shiga Toxin
|
Compound
|
Inferred
|
Explain
|
0.00235
|
33
|
Hydroxychloroquine
|
Compound
|
Inferred
|
Explain
|
0.00232
|
34
|
4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone
|
Compound
|
Inferred
|
Explain
|
0.00231
|
35
|
Dicumarol
|
Compound
|
Inferred
|
Explain
|
0.00231
|
36
|
MAPK1 gene
|
Gene
|
Inferred
|
Explain
|
0.00228
|
37
|
Cyclopentane
|
Compound
|
Inferred
|
Explain
|
0.00226
|
38
|
MAPK3 gene
|
Gene
|
Inferred
|
Explain
|
0.00226
|
39
|
nonane
|
Compound
|
Inferred
|
Explain
|
0.00225
|
40
|
N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide
|
Compound
|
Inferred
|
Explain
|
0.00223
|
41
|
tin protoporphyrin IX
|
Compound
|
Inferred
|
Explain
|
0.00221
|
42
|
gastrin 17
|
Compound
|
Inferred
|
Explain
|
0.00218
|
43
|
Caffeic Acid Phenethyl Ester
|
Compound
|
Inferred
|
Explain
|
0.00216
|
44
|
3-xylene
|
Compound
|
Inferred
|
Explain
|
0.00213
|
45
|
Amiloride
|
Compound
|
Inferred
|
Explain
|
0.00213
|
46
|
2,2-bis(4-glycidyloxyphenyl)propane
|
Compound
|
Inferred
|
Explain
|
0.00211
|
47
|
CSF2 gene
|
Gene
|
Inferred
|
Explain
|
0.00211
|
48
|
Neutrophil chemotaxis
|
Function
|
Inferred
|
Explain
|
0.00210
|
49
|
pyrrolidine dithiocarbamic acid
|
Compound
|
Inferred
|
Explain
|
0.00210
|
50
|
1-bromopropane
|
Compound
|
Inferred
|
Explain
|
0.00208
|
51
|
calphostin C
|
Compound
|
Inferred
|
Explain
|
0.00208
|
52
|
15-deoxyprostaglandin J2
|
Compound
|
Inferred
|
Explain
|
0.00203
|
53
|
bafilomycin A1
|
Compound
|
Inferred
|
Explain
|
0.00201
|
54
|
ICAM1 gene
|
Gene
|
Inferred
|
Explain
|
0.00199
|
55
|
prolinedithiocarbamate
|
Compound
|
Inferred
|
Explain
|
0.00198
|
56
|
fluticasone
|
Compound
|
Inferred
|
Explain
|
0.00197
|
57
|
NS 398
|
Compound
|
Inferred
|
Explain
|
0.00197
|
58
|
Ionomycin
|
Compound
|
Inferred
|
Explain
|
0.00191
|
59
|
IFNG gene
|
Gene
|
Inferred
|
Explain
|
0.00191
|
60
|
Cell Nucleus
|
Component
|
Inferred
|
Explain
|
0.00189
|
61
|
MMP9 gene
|
Gene
|
Inferred
|
Explain
|
0.00186
|
62
|
Lipopolysaccharides
|
Compound
|
Inferred
|
Explain
|
0.00182
|
63
|
Cytoplasm
|
Component
|
Inferred
|
Explain
|
0.00182
|
64
|
Zymosan
|
Compound
|
Inferred
|
Explain
|
0.00182
|
65
|
CCL3 gene
|
Gene
|
Inferred
|
Explain
|
0.00181
|
66
|
Acetaldehyde
|
Compound
|
Inferred
|
Explain
|
0.00181
|
67
|
SB 202190
|
Compound
|
Inferred
|
Explain
|
0.00180
|
68
|
Berberine
|
Compound
|
Inferred
|
Explain
|
0.00178
|
69
|
lipopeptidophosphoglycan
|
Compound
|
Inferred
|
Explain
|
0.00178
|
70
|
FOS gene
|
Gene
|
Inferred
|
Explain
|
0.00174
|
71
|
KEGG:hsa05142
|
Pathway
|
Inferred
|
Explain
|
0.00173
|
72
|
chlorobenzene
|
Compound
|
Inferred
|
Explain
|
0.00171
|
73
|
piperine
|
Compound
|
Inferred
|
Explain
|
0.00170
|
74
|
Neurotensin
|
Compound
|
Inferred
|
Explain
|
0.00168
|
75
|
beta-penta-O-galloyl-glucose
|
Compound
|
Inferred
|
Explain
|
0.00165
|
76
|
PD 98059
|
Compound
|
Inferred
|
Explain
|
0.00165
|
77
|
Inflammatory Response
|
Disease
|
Inferred
|
Explain
|
0.00164
|
78
|
CASP3 gene
|
Gene
|
Inferred
|
Explain
|
0.00163
|
79
|
Simvastatin
|
Compound
|
Inferred
|
Explain
|
0.00163
|
80
|
Gliotoxin
|
Compound
|
Inferred
|
Explain
|
0.00161
|
81
|
Cyclosporine
|
Compound
|
Inferred
|
Explain
|
0.00161
|
82
|
Pertussis Toxin
|
Compound
|
Inferred
|
Explain
|
0.00160
|
83
|
Sodium Salicylate
|
Compound
|
Inferred
|
Explain
|
0.00160
|
84
|
Estradiol
|
Compound
|
Inferred
|
Explain
|
0.00160
|
85
|
Benzo(a)pyrene
|
Compound
|
Inferred
|
Explain
|
0.00159
|
86
|
Chloroform
|
Compound
|
Inferred
|
Explain
|
0.00158
|
87
|
Ammonium Chloride
|
Compound
|
Inferred
|
Explain
|
0.00158
|
88
|
CYP1A1 gene
|
Gene
|
Inferred
|
Explain
|
0.00157
|
89
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
Compound
|
Inferred
|
Explain
|
0.00155
|
90
|
moxifloxacin
|
Compound
|
Inferred
|
Explain
|
0.00154
|
91
|
lopinavir
|
Compound
|
Inferred
|
Explain
|
0.00153
|
92
|
IL10 gene
|
Gene
|
Inferred
|
Explain
|
0.00152
|
93
|
hyperforin
|
Compound
|
Inferred
|
Explain
|
0.00152
|
94
|
Tetrachlorodibenzodioxin
|
Compound
|
Inferred
|
Explain
|
0.00151
|
95
|
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt
|
Compound
|
Inferred
|
Explain
|
0.00150
|
96
|
deoxynivalenol
|
Compound
|
Inferred
|
Explain
|
0.00149
|
97
|
1-nitropyrene
|
Compound
|
Inferred
|
Explain
|
0.00148
|
98
|
SB 203580
|
Compound
|
Inferred
|
Explain
|
0.00147
|
99
|
BAY 11-7085
|
Compound
|
Inferred
|
Explain
|
0.00146
|
100
|
Sulfasalazine
|
Compound
|
Inferred
|
Explain
|
0.00146
|
|