von Willebrand Disease

Disease • C0042974

Definition

Hereditary or acquired coagulation disorder characterized by a qualitative or quantitative deficiency of the von Willebrand factor. The latter plays an important role in platelet adhesion. Signs and symptoms include bruises, nose bleeding, gum bleeding fo

Synonyms

von Willebrand Disease • von Willebrand Diseases • von Willebrand's Disease • von Willebrand's Diseases • von Willebrands Disease • von Willebrands Diseases • Angiohemophilia • Hemophilia, Vascular • Vascular hemophilia • Vascular Hemophilias • PSEUDOHEMOPHILIA • WILLEBRAND-JUERGENS DISEASE • Pseudohemophilia type B • Constitutional thrombopathy • Factor VIII deficiency with vascular defect • Angiohemophilias • Angiohemophilia, A • Angiohemophilia, B • Vascular pseudohemophilia • von Willebrand's-Jurgens' disease • von Willebrand • VON WILLEBRAND DIS • VON WILLEBRANDS DIS • von Willebrand Diseases [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

VWF gene    Hemorrhagic Disorders    Blood Coagulation Disorders, Inherited    Coagulation Protein Disorders    Blood Platelet Disorders    von Willebrand Disease, Recessive Form    Von Willebrand disease, platelet type    VON WILLEBRAND DISEASE, X-LINKED FORM    von Willebrand Disease, Type 3   

Related concepts

# Concept name Type Relation Support Score
1 von Willebrand Disease, Type 3 Disease Known Explain 52.57362
2 VON WILLEBRAND DISEASE, X-LINKED FORM Disease Known Explain 52.57362
3 Von Willebrand disease, platelet type Disease Known Explain 49.00145
4 von Willebrand Disease, Recessive Form Disease Known Explain 47.28204
5 VWF gene Gene Known Explain 45.76899
6 Coagulation Protein Disorders Disease Known Explain 39.12110
7 Blood Coagulation Disorders, Inherited Disease Known Explain 34.87238
8 Hemorrhagic Disorders Disease Known Explain 30.28635
9 Blood Platelet Disorders Disease Known Explain 27.86182
10 Hypoprothrombinemias Disease Inferred Explain 3.02237
11 Factor VII Deficiency Disease Inferred Explain 3.01670
12 Factor V Deficiency Disease Inferred Explain 3.00573
13 Factor X Deficiency Disease Inferred Explain 2.98356
14 Factor XI Deficiency Disease Inferred Explain 2.98068
15 Factor XII Deficiency Disease Inferred Explain 2.93361
16 Factor XIII Deficiency Disease Inferred Explain 2.76995
17 GP1BA gene Gene Inferred Explain 2.73725
18 Hemophilia B Disease Inferred Explain 2.66140
19 Afibrinogenemia Disease Inferred Explain 2.61130
20 Thrombasthenia Disease Inferred Explain 2.43626
21 Hemophilia A Disease Inferred Explain 2.33067
22 VWF wt Allele Gene Inferred Explain 2.11590
23 Bernard-Soulier Syndrome Disease Inferred Explain 2.04398
24 Gray Platelet Syndrome Disease Inferred Explain 1.87202
25 Activated Protein C Resistance Disease Inferred Explain 1.86466
26 Platelet Storage Pool Deficiency Disease Inferred Explain 1.70730
27 Blood Coagulation Disorders Disease Inferred Explain 1.30660
28 Hermanski-Pudlak Syndrome Disease Inferred Explain 1.01800
29 Wiskott-Aldrich Syndrome Disease Inferred Explain 0.78891
30 Thrombocytosis Disease Inferred Explain 0.76830
31 PLATELET DISORDER, FAMILIAL, WITH ASSOCIATED MYELOID MALIGNANCY Disease Inferred Explain 0.69554
32 STORMORKEN SYNDROME Disease Inferred Explain 0.59778
33 Thrombocythemia, Essential Disease Inferred Explain 0.52641
34 Hematological Disease Disease Inferred Explain 0.48229
35 Disseminated Intravascular Coagulation Disease Inferred Explain 0.33345
36 Antithrombin III Deficiency Disease Inferred Explain 0.29493
37 Thrombocytopenia Disease Inferred Explain 0.29250
38 Protein C Deficiency Disease Inferred Explain 0.27641
39 Vitamin K Deficiency Disease Inferred Explain 0.27042
40 Thrombophilia Disease Inferred Explain 0.26639
41 Waterhouse-Friderichsen Syndrome Disease Inferred Explain 0.20898
42 F7 gene Gene Inferred Explain 0.20179
43 F11 gene Gene Inferred Explain 0.18733
44 Purpura, Thrombocytopenic, Idiopathic Disease Inferred Explain 0.18578
45 F13B gene Gene Inferred Explain 0.14596
46 F9 gene Gene Inferred Explain 0.14116
47 Hereditary factor I deficiency disease Disease Inferred Explain 0.13683
48 ITGA2 gene Gene Inferred Explain 0.12603
49 F12 gene Gene Inferred Explain 0.10927
50 F5 gene Gene Inferred Explain 0.10268
51 GIANT PLATELET SYNDROME WITH THROMBOCYTOPENIA Disease Inferred Explain 0.10249
52 GP9 gene Gene Inferred Explain 0.09820
53 Pupil constriction Function Inferred Explain 0.09557
54 Pupil constriction observed Disease Inferred Explain 0.09557
55 Genetic Diseases, X-Linked Disease Inferred Explain 0.09349
56 Vascular Hemostatic Disorders Disease Inferred Explain 0.09048
57 Miosis disorder Disease Inferred Explain 0.08334
58 Malnutrition Disease Inferred Explain 0.08302
59 FGA gene Gene Inferred Explain 0.07417
60 F13A1 gene Gene Inferred Explain 0.07283
61 F10 gene Gene Inferred Explain 0.07225
62 FGB gene Gene Inferred Explain 0.06938
63 Blood Platelets Other Inferred Explain 0.06768
64 F2 gene Gene Inferred Explain 0.06504
65 ITGA2B gene Gene Inferred Explain 0.06191
66 CFI gene Gene Inferred Explain 0.06112
67 Asplenia Other Inferred Explain 0.05804
68 GP1BB gene Gene Inferred Explain 0.05717
69 ATAXIA, SPASTIC, WITH CONGENITAL MIOSIS Disease Inferred Explain 0.05702
70 PLA2G4A gene Gene Inferred Explain 0.05645
71 Microcoria, congenital Other Inferred Explain 0.05478
72 P2RX1 gene Gene Inferred Explain 0.05390
73 blood coagulation, intrinsic pathway Function Inferred Explain 0.05042
74 OPHTHALMOPLEGIA TOTALIS WITH PTOSIS AND MIOSIS Disease Inferred Explain 0.04598
75 Myeloproliferative disease Disease Inferred Explain 0.04463
76 Lymphopenia Disease Inferred Explain 0.04422
77 Blood Protein Disorders Disease Inferred Explain 0.04320
78 Genetic Diseases, Inborn Disease Inferred Explain 0.03731
79 F8 gene Gene Inferred Explain 0.03662
80 MTHFR gene Gene Inferred Explain 0.03480
81 PROC gene Gene Inferred Explain 0.03061
82 Protein S Deficiency Disease Inferred Explain 0.02883
83 ITGB3 gene Gene Inferred Explain 0.02594
84 HEMOPHILIA A WITH VASCULAR ABNORMALITY Disease Inferred Explain 0.02585
85 Ivemark syndrome Other Inferred Explain 0.02130
86 Purpura Disease Inferred Explain 0.02031
87 Gestodene Compound Inferred Explain 0.01929
88 Immunologic Deficiency Syndromes Disease Inferred Explain 0.01720
89 nilestriol Compound Inferred Explain 0.01685
90 Anti-Retroviral Agents Compound Inferred Explain 0.01598
91 Mercilon Compound Inferred Explain 0.01546
92 von Willebrand factor Domain Inferred Explain 0.01517
93 Weibel-Palade Bodies Component Inferred Explain 0.01349
94 Go 6983 Compound Inferred Explain 0.01289
95 propylene dichloride Compound Inferred Explain 0.01247
96 cell-substrate adhesion Function Inferred Explain 0.01245
97 JAK2 gene Gene Inferred Explain 0.01209
98 platelet alpha granule Component Inferred Explain 0.01204
99 ECM-receptor interaction - Homo sapiens (human) Pathway Inferred Explain 0.01167
100 GP5 gene Gene Inferred Explain 0.01125