Silicosis

Disease • C0037116

Definition

An occupational lung disorder caused by the inhalation of silica dust. It results in the inflammation and scarring of the upper lobes of the lungs. It may be an acute or chronic disorder. In the acute form, patients develop shortness of breath, fever, and

Synonyms

Silicosis • Silicoses • Silicosis NOS • Pneumoconiosis due to other silica or silicates • Silica pneumocon NEC • Pneumoconiosis due to dust containing silica • Silicotic fibrosis of lung • Silicosis [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

Pneumoconiosis    Silicotuberculosis    Anthracosilicosis   

Related concepts

# Concept name Type Relation Support Score
1 Anthracosilicosis Disease Known Explain 648.90076
2 Pneumoconiosis Disease Known Explain 495.90909
3 Silicotuberculosis Disease Known Explain 456.41851
4 Anthracosis Disease Inferred Explain 376.33039
5 Tuberculosis, Pulmonary Disease Inferred Explain 28.50549
6 Caplan Syndrome Disease Inferred Explain 23.86589
7 Asbestosis Disease Inferred Explain 18.98213
8 Berylliosis Other Inferred Explain 11.59477
9 Lung Injury Other Inferred Explain 9.55180
10 Lung Diseases, Interstitial Disease Inferred Explain 8.38178
11 Occupational Diseases Disease Inferred Explain 8.25853
12 Rheumatoid Arthritis Disease Inferred Explain 0.98954
13 Chrysotile Compound Inferred Explain 0.61336
14 Lung diseases Disease Inferred Explain 0.22107
15 Extrinsic allergic alveolitis Disease Inferred Explain 0.21570
16 HLA-DPB2 gene Gene Inferred Explain 0.21566
17 Radiation Pneumonitis Other Inferred Explain 0.20738
18 Bird Fancier's Lung Disease Inferred Explain 0.19024
19 SERPINA1 gene Gene Inferred Explain 0.18769
20 BTNL2 gene Gene Inferred Explain 0.15894
21 Sleep Disorders, Circadian Rhythm Disease Inferred Explain 0.15379
22 Inert Gas Narcosis Other Inferred Explain 0.14044
23 Persian Gulf Syndrome Disease Inferred Explain 0.13623
24 GSTT1 gene Gene Inferred Explain 0.13203
25 Respiratory Tract Infections Disease Inferred Explain 0.13185
26 Beryllium Compound Inferred Explain 0.12618
27 Laboratory Infection Disease Inferred Explain 0.12069
28 High Pressure Neurological Syndrome Disease Inferred Explain 0.11751
29 Hand-Arm Vibration Syndrome Other Inferred Explain 0.10927
30 NOS2 gene Gene Inferred Explain 0.10667
31 Tuberculosis Disease Inferred Explain 0.09450
32 Sarcoidosis, Pulmonary Disease Inferred Explain 0.08608
33 Dermatitis, Occupational Disease Inferred Explain 0.08042
34 Wegener Granulomatosis Disease Inferred Explain 0.07397
35 Idiopathic Interstitial Pneumonias Disease Inferred Explain 0.07209
36 Ventilator-Induced Lung Injury Other Inferred Explain 0.07189
37 Desquamative interstitial pneumonia Disease Inferred Explain 0.07128
38 Histiocytosis, Langerhans-Cell Disease Inferred Explain 0.06969
39 Prednisone Compound Inferred Explain 0.06930
40 Anti-Glomerular Basement Membrane Disease Disease Inferred Explain 0.06746
41 HLA-DPB1 gene Gene Inferred Explain 0.06259
42 Agricultural Workers' Diseases Disease Inferred Explain 0.05607
43 Thoracic Injuries Other Inferred Explain 0.05595
44 Polyvinyl Chloride Compound Inferred Explain 0.05460
45 SURFACTANT METABOLISM DYSFUNCTION, PULMONARY, 1 Disease Inferred Explain 0.05340
46 Gas Poisoning Other Inferred Explain 0.05049
47 HLA-DRB1 gene Gene Inferred Explain 0.04726
48 CD28 gene Gene Inferred Explain 0.04096
49 Meconium Aspiration Syndrome Disease Inferred Explain 0.03843
50 Chronobiology Disorders Disease Inferred Explain 0.03696
51 Acute Lung Injury Other Inferred Explain 0.03528
52 Vinyl Chloride Compound Inferred Explain 0.03430
53 Sarcoidosis Disease Inferred Explain 0.03356
54 IL2RA gene Gene Inferred Explain 0.03158
55 Jet Lag Syndrome Disease Inferred Explain 0.03021
56 Toluene 2,4-Diisocyanate Compound Inferred Explain 0.02854
57 GCLM gene Gene Inferred Explain 0.02676
58 ACE gene Gene Inferred Explain 0.02585
59 Hydrochloric Acid Compound Inferred Explain 0.02161
60 Nitrofurantoin Compound Inferred Explain 0.02110
61 XRCC1 gene Gene Inferred Explain 0.02059
62 Radiation injury Other Inferred Explain 0.01911
63 Farmer's Lung Disease Inferred Explain 0.01695
64 Silo Filler's Disease Disease Inferred Explain 0.01695
65 Pneumonia, Ventilator-Associated Disease Inferred Explain 0.01505
66 MPO gene Gene Inferred Explain 0.01441
67 CNS disorder Disease Inferred Explain 0.01282
68 ERCC2 gene Gene Inferred Explain 0.01261
69 Benzene Compound Inferred Explain 0.01200
70 Dyssomnias Disease Inferred Explain 0.01198
71 Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Disease Inferred Explain 0.01191
72 Infection Disease Inferred Explain 0.01165
73 beryllium sulfate Compound Inferred Explain 0.01162
74 Eosinophilic Granuloma Disease Inferred Explain 0.01144
75 Ciprofloxacin Compound Inferred Explain 0.01066
76 Bronchopulmonary Dysplasia Disease Inferred Explain 0.01009
77 NQO1 gene Gene Inferred Explain 0.00983
78 Rib Fractures Other Inferred Explain 0.00970
79 TGFB1 gene Gene Inferred Explain 0.00870
80 Histiocytosis Disease Inferred Explain 0.00793
81 FCGR3B gene Gene Inferred Explain 0.00720
82 Pneumonia Disease Inferred Explain 0.00701
83 TNF gene Gene Inferred Explain 0.00648
84 IL6 gene Gene Inferred Explain 0.00643
85 Respiratory Hypersensitivity Disease Inferred Explain 0.00554
86 Glomerulonephritis Disease Inferred Explain 0.00542
87 Dermatitis, Allergic Contact Disease Inferred Explain 0.00516
88 CYP2D6 gene Gene Inferred Explain 0.00495
89 Autoimmune Diseases Disease Inferred Explain 0.00483
90 nabam Compound Inferred Explain 0.00435
91 polymarcine Compound Inferred Explain 0.00435
92 propineb Compound Inferred Explain 0.00435
93 PON1 gene Gene Inferred Explain 0.00428
94 CYP1A1 gene Gene Inferred Explain 0.00388
95 Bronchiolitis Obliterans Organizing Pneumonia Disease Inferred Explain 0.00384
96 Pulmonary Alveolar Proteinosis Disease Inferred Explain 0.00383
97 Pneumonia, Interstitial Disease Inferred Explain 0.00327
98 Zineb Compound Inferred Explain 0.00313
99 Cross Infection Disease Inferred Explain 0.00306
100 dyrene Compound Inferred Explain 0.00281