|
#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
HYPOURICEMIA, HYPERCALCINURIA, AND DECREASED BONE DENSITY
|
Disease
|
Known
|
Explain
|
44.99349
|
|
2
|
Familial idiopathic hypercalciuria
|
Other
|
Known
|
Explain
|
28.99929
|
|
3
|
HYPERPARATHYROIDISM, NEONATAL SELF-LIMITED PRIMARY, WITH HYPERCALCIURIA
|
Disease
|
Known
|
Explain
|
25.85786
|
|
4
|
autosomal recessive hypophosphatemic bone disease
|
Disease
|
Known
|
Explain
|
23.74509
|
|
5
|
Bartter syndrome, antenatal , type 2
|
Disease
|
Known
|
Explain
|
23.53199
|
|
6
|
Bartter syndrome, antenatal type 1
|
Disease
|
Known
|
Explain
|
23.06884
|
|
7
|
PROTEINURIA, LOW MOLECULAR WEIGHT, WITH HYPERCALCIURIA AND NEPHROCALCINOSIS
|
Disease
|
Known
|
Explain
|
20.46124
|
|
8
|
HYPOMAGNESEMIA 5, RENAL, WITH OCULAR INVOLVEMENT
|
Disease
|
Known
|
Explain
|
19.35937
|
|
9
|
Hypouricemia
|
Disease
|
Inferred
|
Explain
|
17.22581
|
|
10
|
Urological Manifestations
|
Disease
|
Known
|
Explain
|
15.09891
|
|
11
|
Primary hypomagnesemia (disorder)
|
Disease
|
Known
|
Explain
|
14.03401
|
|
12
|
Furosemide
|
Compound
|
Known
|
Explain
|
7.28708
|
|
13
|
SLC34A1 gene
|
Gene
|
Known
|
Explain
|
6.32767
|
|
14
|
Genticin
|
Compound
|
Known
|
Explain
|
6.26388
|
|
15
|
Renal hypouricemia
|
Disease
|
Inferred
|
Explain
|
5.51891
|
|
16
|
ADCY10 gene
|
Gene
|
Inferred
|
Explain
|
3.46470
|
|
17
|
Hypophosphatemic Rickets
|
Disease
|
Inferred
|
Explain
|
3.45700
|
|
18
|
Hypokalemic alkalosis
|
Disease
|
Inferred
|
Explain
|
2.71313
|
|
19
|
SLC34A3 gene
|
Gene
|
Inferred
|
Explain
|
2.22057
|
|
20
|
Bartter Disease
|
Disease
|
Inferred
|
Explain
|
1.84792
|
|
21
|
Nephrocalcinosis
|
Disease
|
Inferred
|
Explain
|
1.57456
|
|
22
|
Kidney
|
Other
|
Inferred
|
Explain
|
1.14631
|
|
23
|
Hyperparathyroidism
|
Disease
|
Inferred
|
Explain
|
0.97505
|
|
24
|
HYPOMAGNESEMIA
|
Disease
|
Inferred
|
Explain
|
0.86182
|
|
25
|
Proteinuria
|
Disease
|
Inferred
|
Explain
|
0.57528
|
|
26
|
KCNJ1 gene
|
Gene
|
Inferred
|
Explain
|
0.56986
|
|
27
|
HYPOKALEMIA, FAMILIAL
|
Disease
|
Inferred
|
Explain
|
0.51130
|
|
28
|
Proteinuria Adverse Event
|
Disease
|
Inferred
|
Explain
|
0.46102
|
|
29
|
SLC22A12 gene
|
Gene
|
Inferred
|
Explain
|
0.41436
|
|
30
|
Polyuria
|
Disease
|
Inferred
|
Explain
|
0.38133
|
|
31
|
Urinary Incontinence
|
Disease
|
Inferred
|
Explain
|
0.36081
|
|
32
|
SLC2A9 gene
|
Gene
|
Inferred
|
Explain
|
0.32117
|
|
33
|
Oliguria
|
Disease
|
Inferred
|
Explain
|
0.29315
|
|
34
|
Urination Disorders
|
Disease
|
Inferred
|
Explain
|
0.28528
|
|
35
|
SLC12A1 gene
|
Gene
|
Inferred
|
Explain
|
0.27928
|
|
36
|
Overactive Bladder
|
Disease
|
Inferred
|
Explain
|
0.25432
|
|
37
|
CLDN19 gene
|
Gene
|
Inferred
|
Explain
|
0.17708
|
|
38
|
CLCN5 gene
|
Gene
|
Inferred
|
Explain
|
0.16366
|
|
39
|
Dietary Magnesium
|
Compound
|
Inferred
|
Explain
|
0.13968
|
|
40
|
Hyperparathyroidism, Secondary
|
Disease
|
Inferred
|
Explain
|
0.12163
|
|
41
|
Hypomagnesemia 2, renal
|
Disease
|
Inferred
|
Explain
|
0.10355
|
|
42
|
HYPOPHOSPHATEMIC RICKETS, AUTOSOMAL RECESSIVE, 1
|
Disease
|
Inferred
|
Explain
|
0.10019
|
|
43
|
HYPOPHOSPHATEMIC RICKETS, X-LINKED RECESSIVE
|
Disease
|
Inferred
|
Explain
|
0.09951
|
|
44
|
Megaloblastic anemia due to inborn errors of metabolism
|
Disease
|
Inferred
|
Explain
|
0.09813
|
|
45
|
Hypercalcemia
|
Disease
|
Inferred
|
Explain
|
0.09656
|
|
46
|
Autosomal dominant hypophosphatemic rickets
|
Other
|
Inferred
|
Explain
|
0.09034
|
|
47
|
Hyperaldosteronism
|
Disease
|
Inferred
|
Explain
|
0.09032
|
|
48
|
FXYD2 gene
|
Gene
|
Inferred
|
Explain
|
0.07775
|
|
49
|
Hypophosphatemia
|
Disease
|
Inferred
|
Explain
|
0.07683
|
|
50
|
terodiline
|
Compound
|
Inferred
|
Explain
|
0.07266
|
|
51
|
Urinary Bladder Diseases
|
Disease
|
Inferred
|
Explain
|
0.06822
|
|
52
|
Bartter syndrome, type 3
|
Disease
|
Inferred
|
Explain
|
0.06811
|
|
53
|
Hypokalemia
|
Disease
|
Inferred
|
Explain
|
0.06648
|
|
54
|
Familial hypophosphatemic bone disease
|
Disease
|
Inferred
|
Explain
|
0.06584
|
|
55
|
CLDN16 gene
|
Gene
|
Inferred
|
Explain
|
0.06546
|
|
56
|
Donnai Barrow syndrome
|
Disease
|
Inferred
|
Explain
|
0.06365
|
|
57
|
NPS R-467
|
Compound
|
Inferred
|
Explain
|
0.06203
|
|
58
|
BARTTER SYNDROME, TYPE 4A
|
Disease
|
Inferred
|
Explain
|
0.05377
|
|
59
|
Bedwetting
|
Disease
|
Inferred
|
Explain
|
0.05315
|
|
60
|
HYPOMAGNESEMIC TETANY
|
Disease
|
Inferred
|
Explain
|
0.05297
|
|
61
|
Signs and Symptoms
|
Disease
|
Inferred
|
Explain
|
0.04835
|
|
62
|
REN gene
|
Gene
|
Inferred
|
Explain
|
0.04794
|
|
63
|
Tacrolimus
|
Compound
|
Inferred
|
Explain
|
0.04786
|
|
64
|
Hypotension, Orthostatic
|
Disease
|
Inferred
|
Explain
|
0.04699
|
|
65
|
Renal Tubular Transport, Inborn Errors
|
Disease
|
Inferred
|
Explain
|
0.04660
|
|
66
|
HYPOMAGNESEMIA, HYPERTENSION, AND HYPERCHOLESTEROLEMIA, MITOCHONDRIAL
|
Disease
|
Inferred
|
Explain
|
0.04572
|
|
67
|
Blue diaper syndrome
|
Disease
|
Inferred
|
Explain
|
0.04262
|
|
68
|
Magnesium
|
Compound
|
Inferred
|
Explain
|
0.04028
|
|
69
|
Hypoproteinemia
|
Disease
|
Inferred
|
Explain
|
0.03878
|
|
70
|
Kidney Diseases
|
Disease
|
Inferred
|
Explain
|
0.03853
|
|
71
|
Hypertension induced by pregnancy
|
Disease
|
Inferred
|
Explain
|
0.03486
|
|
72
|
Dyspnea
|
Disease
|
Inferred
|
Explain
|
0.03019
|
|
73
|
Enamel-renal syndrome
|
Disease
|
Inferred
|
Explain
|
0.02887
|
|
74
|
Hypotension
|
Disease
|
Inferred
|
Explain
|
0.02680
|
|
75
|
Sulfanilamides
|
Compound
|
Inferred
|
Explain
|
0.02513
|
|
76
|
hearing impairment
|
Disease
|
Inferred
|
Explain
|
0.02485
|
|
77
|
Respiratory Distress Syndrome, Adult
|
Disease
|
Inferred
|
Explain
|
0.02432
|
|
78
|
Vesico-Ureteral Reflux
|
Disease
|
Inferred
|
Explain
|
0.02398
|
|
79
|
CASR gene
|
Gene
|
Inferred
|
Explain
|
0.02228
|
|
80
|
RENAL TUBULAR ACIDOSIS, DISTAL, WITH NEPHROCALCINOSIS, SHORT STATURE, MENTAL RETARDATION, AND DISTINCTIVE FACIES
|
Disease
|
Inferred
|
Explain
|
0.02153
|
|
81
|
HYPOPHOSPHATEMIA, RENAL, WITH INTRACEREBRAL CALCIFICATIONS
|
Disease
|
Inferred
|
Explain
|
0.02034
|
|
82
|
Calcinosis
|
Disease
|
Inferred
|
Explain
|
0.01925
|
|
83
|
VENTRICULOMEGALY WITH DEFECTS OF THE RADIUS AND KIDNEY
|
Disease
|
Inferred
|
Explain
|
0.01899
|
|
84
|
HYPERPHOSPHATEMIA, POLYURIA, AND SEIZURES
|
Disease
|
Inferred
|
Explain
|
0.01766
|
|
85
|
sodium-dependent phosphate transmembrane transporter activity
|
Function
|
Inferred
|
Explain
|
0.01752
|
|
86
|
Glycosuria, Renal
|
Disease
|
Inferred
|
Explain
|
0.01681
|
|
87
|
response to magnesium ion
|
Function
|
Inferred
|
Explain
|
0.01619
|
|
88
|
Glucocorticoid-remediable aldosteronism
|
Disease
|
Inferred
|
Explain
|
0.01578
|
|
89
|
Adrenal Gland Hyperfunction
|
Disease
|
Inferred
|
Explain
|
0.01560
|
|
90
|
Torsades de Pointes
|
Disease
|
Inferred
|
Explain
|
0.01475
|
|
91
|
MAGNESIUM, ELEVATED RED CELL
|
Disease
|
Inferred
|
Explain
|
0.01425
|
|
92
|
Lisinopril
|
Compound
|
Inferred
|
Explain
|
0.01337
|
|
93
|
Renal Osteodystrophy
|
Disease
|
Inferred
|
Explain
|
0.01303
|
|
94
|
X- linked recessive
|
Disease
|
Inferred
|
Explain
|
0.01299
|
|
95
|
Fanconi Syndrome
|
Disease
|
Inferred
|
Explain
|
0.01239
|
|
96
|
Heart failure
|
Disease
|
Inferred
|
Explain
|
0.01231
|
|
97
|
Reperfusion Injury
|
Other
|
Inferred
|
Explain
|
0.01208
|
|
98
|
Urinary tract
|
Other
|
Inferred
|
Explain
|
0.01154
|
|
99
|
Dinoprostone
|
Compound
|
Inferred
|
Explain
|
0.01151
|
|
100
|
brush border membrane
|
Component
|
Inferred
|
Explain
|
0.01123
|