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Fetal Alcohol Syndrome
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Disease • C0015923
Definition
A syndrome that can develop in infants whose mothers consumed alcohol during pregnancy. Manifestations of this syndrome include low birth weight, failure to thrive, developmental defects, organ dysfunction, mental deficiencies, behavioral problems and poo
Synonyms
Fetal Alcohol Syndrome • Fetal Alcohol Syndromes • Alcohol affecting fetus or newborn via placenta or breast milk • Fetal alcohol syndrome (dysmorphic) • alcohol related birth defects • fetal alcohol effects • FAS • FAE • ARBD • Maternl alc aff NB/fetus • Fetal Alcohol Syndrome [Disease/Finding]
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Ethanol
Fetal Diseases
PLUNC gene
Alcohol-Induced Disorders
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Related concepts
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#
|
Concept name
|
Type
|
Relation
|
Support
|
Score
|
|
1
|
PLUNC gene
|
Gene
|
Known
|
Explain
|
152.59513
|
|
2
|
Alcohol-Induced Disorders
|
Disease
|
Known
|
Explain
|
124.70283
|
|
3
|
Fetal Diseases
|
Disease
|
Known
|
Explain
|
83.84261
|
|
4
|
Ethanol
|
Compound
|
Known
|
Explain
|
18.28841
|
|
5
|
Lipid-binding serum glycoprotein, N-terminal
|
Domain
|
Inferred
|
Explain
|
2.53503
|
|
6
|
Bactericidal permeability-increasing protein, alpha/beta domain
|
Domain
|
Inferred
|
Explain
|
2.47705
|
|
7
|
Alcohol-Related Disorders
|
Disease
|
Inferred
|
Explain
|
2.35420
|
|
8
|
Psychoses, Alcoholic
|
Disease
|
Inferred
|
Explain
|
2.04156
|
|
9
|
Pancreatitis, Alcoholic
|
Disease
|
Inferred
|
Explain
|
1.98788
|
|
10
|
Alcohol-Induced Disorders, Nervous System
|
Disease
|
Inferred
|
Explain
|
1.76999
|
|
11
|
Cardiomyopathy, Alcoholic
|
Disease
|
Inferred
|
Explain
|
1.76808
|
|
12
|
Fetal Hypoxia
|
Disease
|
Inferred
|
Explain
|
1.32030
|
|
13
|
Alcoholic Liver Diseases
|
Disease
|
Inferred
|
Explain
|
1.17469
|
|
14
|
Chorioamnionitis
|
Disease
|
Inferred
|
Explain
|
1.03545
|
|
15
|
Fetal Macrosomia
|
Disease
|
Inferred
|
Explain
|
0.94515
|
|
16
|
Nuchal Cord
|
Disease
|
Inferred
|
Explain
|
0.88902
|
|
17
|
Fetal Nutrition Disorders
|
Disease
|
Inferred
|
Explain
|
0.84758
|
|
18
|
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
|
Disease
|
Inferred
|
Explain
|
0.65110
|
|
19
|
Pregnancy Complications
|
Disease
|
Inferred
|
Explain
|
0.63268
|
|
20
|
Meconium Aspiration Syndrome
|
Disease
|
Inferred
|
Explain
|
0.62732
|
|
21
|
Fetal Growth Retardation
|
Disease
|
Inferred
|
Explain
|
0.59852
|
|
22
|
Erythroblastosis, Fetal
|
Disease
|
Inferred
|
Explain
|
0.50671
|
|
23
|
Anoxia
|
Disease
|
Inferred
|
Explain
|
0.41195
|
|
24
|
Lipid Binding
|
Function
|
Inferred
|
Explain
|
0.34840
|
|
25
|
Psychoses, Substance-Induced
|
Disease
|
Inferred
|
Explain
|
0.34683
|
|
26
|
Placenta Disorders
|
Disease
|
Inferred
|
Explain
|
0.26511
|
|
27
|
UBQLN4 gene
|
Gene
|
Inferred
|
Explain
|
0.26314
|
|
28
|
Fetal Membranes, Premature Rupture
|
Disease
|
Inferred
|
Explain
|
0.18872
|
|
29
|
Alcohol Withdrawal Delirium
|
Disease
|
Inferred
|
Explain
|
0.18291
|
|
30
|
Innate Immune Response
|
Disease
|
Inferred
|
Explain
|
0.17954
|
|
31
|
Alcohol Amnestic Disorder
|
Disease
|
Inferred
|
Explain
|
0.16765
|
|
32
|
Pancreatitis
|
Disease
|
Inferred
|
Explain
|
0.14967
|
|
33
|
Pregnancy in Diabetics
|
Disease
|
Inferred
|
Explain
|
0.10483
|
|
34
|
Obstetric Labor Complications
|
Disease
|
Inferred
|
Explain
|
0.10153
|
|
35
|
Birth Weight
|
Other
|
Inferred
|
Explain
|
0.09685
|
|
36
|
Gestational Diabetes
|
Disease
|
Inferred
|
Explain
|
0.08372
|
|
37
|
Alcohol Withdrawal Seizures
|
Disease
|
Inferred
|
Explain
|
0.08371
|
|
38
|
Alcoholic Neuropathy
|
Disease
|
Inferred
|
Explain
|
0.08123
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|
39
|
Neonatal disorder
|
Disease
|
Inferred
|
Explain
|
0.07649
|
|
40
|
Lipid-binding serum glycoprotein, C-terminal
|
Domain
|
Inferred
|
Explain
|
0.07340
|
|
41
|
Lipid-binding serum glycoprotein, conserved site
|
Domain
|
Inferred
|
Explain
|
0.07262
|
|
42
|
Substance Withdrawal Syndrome
|
Disease
|
Inferred
|
Explain
|
0.06926
|
|
43
|
Signs and Symptoms, Respiratory
|
Disease
|
Inferred
|
Explain
|
0.06912
|
|
44
|
Malnutrition
|
Disease
|
Inferred
|
Explain
|
0.06045
|
|
45
|
molecular_function
|
Function
|
Inferred
|
Explain
|
0.05938
|
|
46
|
BPIL3 gene
|
Gene
|
Inferred
|
Explain
|
0.05333
|
|
47
|
IPR021193
|
Domain
|
Inferred
|
Explain
|
0.05306
|
|
48
|
Substance-Related Disorders
|
Disease
|
Inferred
|
Explain
|
0.05303
|
|
49
|
Fatty Liver, Alcoholic
|
Disease
|
Inferred
|
Explain
|
0.05271
|
|
50
|
Acetaldehyde
|
Compound
|
Inferred
|
Explain
|
0.05116
|
|
51
|
Neurotoxicity Syndromes
|
Other
|
Inferred
|
Explain
|
0.05079
|
|
52
|
Cholesteryl ester transfer
|
Domain
|
Inferred
|
Explain
|
0.04955
|
|
53
|
BPIL2 gene
|
Gene
|
Inferred
|
Explain
|
0.04831
|
|
54
|
tezosentan
|
Compound
|
Inferred
|
Explain
|
0.04711
|
|
55
|
Liver Cirrhosis, Alcoholic
|
Disease
|
Inferred
|
Explain
|
0.04642
|
|
56
|
BPIL1 gene
|
Gene
|
Inferred
|
Explain
|
0.04439
|
|
57
|
Complications of Diabetes Mellitus
|
Disease
|
Inferred
|
Explain
|
0.04349
|
|
58
|
Cardiomyopathies
|
Disease
|
Inferred
|
Explain
|
0.04136
|
|
59
|
varenicline
|
Compound
|
Inferred
|
Explain
|
0.03763
|
|
60
|
INTRAUTERINE GROWTH RETARDATION, METAPHYSEAL DYSPLASIA, ADRENAL HYPOPLASIA CONGENITA, AND GENITAL ANOMALIES
|
Disease
|
Inferred
|
Explain
|
0.03446
|
|
61
|
Placenta Accreta
|
Disease
|
Inferred
|
Explain
|
0.03355
|
|
62
|
Placenta Previa
|
Disease
|
Inferred
|
Explain
|
0.03355
|
|
63
|
Body Weight
|
Other
|
Inferred
|
Explain
|
0.03216
|
|
64
|
Estradiol
|
Compound
|
Inferred
|
Explain
|
0.03190
|
|
65
|
Abruptio Placentae
|
Disease
|
Inferred
|
Explain
|
0.02938
|
|
66
|
BPI gene
|
Gene
|
Inferred
|
Explain
|
0.02926
|
|
67
|
Respiration Disorders
|
Disease
|
Inferred
|
Explain
|
0.02922
|
|
68
|
Wernicke Encephalopathy
|
Disease
|
Inferred
|
Explain
|
0.02893
|
|
69
|
PLTP gene
|
Gene
|
Inferred
|
Explain
|
0.02892
|
|
70
|
Tetrachlorodibenzodioxin
|
Compound
|
Inferred
|
Explain
|
0.02822
|
|
71
|
Hepatitis, Alcoholic
|
Disease
|
Inferred
|
Explain
|
0.02812
|
|
72
|
Chlormethiazole
|
Compound
|
Inferred
|
Explain
|
0.02807
|
|
73
|
extracellular region
|
Component
|
Inferred
|
Explain
|
0.02704
|
|
74
|
Lung Injury
|
Other
|
Inferred
|
Explain
|
0.02605
|
|
75
|
Lambotte syndrome
|
Disease
|
Inferred
|
Explain
|
0.02413
|
|
76
|
Wernicke-Korsakoff Syndrome
|
Disease
|
Inferred
|
Explain
|
0.02263
|
|
77
|
CETP gene
|
Gene
|
Inferred
|
Explain
|
0.01986
|
|
78
|
Amnesia
|
Disease
|
Inferred
|
Explain
|
0.01495
|
|
79
|
Congenital Abnormality
|
Other
|
Inferred
|
Explain
|
0.01487
|
|
80
|
PNPLA3 gene
|
Gene
|
Inferred
|
Explain
|
0.01443
|
|
81
|
Pyle metaphyseal dysplasia
|
Disease
|
Inferred
|
Explain
|
0.01401
|
|
82
|
LBP gene
|
Gene
|
Inferred
|
Explain
|
0.01386
|
|
83
|
SERPINH1 gene
|
Gene
|
Inferred
|
Explain
|
0.01351
|
|
84
|
puerarin
|
Compound
|
Inferred
|
Explain
|
0.01316
|
|
85
|
Psychotic Disorders
|
Disease
|
Inferred
|
Explain
|
0.01221
|
|
86
|
Genetic Diseases, Inborn
|
Disease
|
Inferred
|
Explain
|
0.01189
|
|
87
|
Alcoholic Intoxication, Chronic
|
Disease
|
Inferred
|
Explain
|
0.01178
|
|
88
|
Hydrops Fetalis
|
Disease
|
Inferred
|
Explain
|
0.01145
|
|
89
|
Silymarin
|
Compound
|
Inferred
|
Explain
|
0.01143
|
|
90
|
Lead
|
Compound
|
Inferred
|
Explain
|
0.01142
|
|
91
|
Memory Disorders
|
Disease
|
Inferred
|
Explain
|
0.01090
|
|
92
|
Kernicterus
|
Disease
|
Inferred
|
Explain
|
0.00977
|
|
93
|
Poisoning
|
Other
|
Inferred
|
Explain
|
0.00949
|
|
94
|
MIR212 gene
|
Gene
|
Inferred
|
Explain
|
0.00874
|
|
95
|
Growth Disorders
|
Disease
|
Inferred
|
Explain
|
0.00870
|
|
96
|
Blood Group Incompatibility
|
Disease
|
Inferred
|
Explain
|
0.00860
|
|
97
|
Polyneuropathy
|
Disease
|
Inferred
|
Explain
|
0.00820
|
|
98
|
Fatty Liver
|
Disease
|
Inferred
|
Explain
|
0.00722
|
|
99
|
Thiamine Deficiency
|
Disease
|
Inferred
|
Explain
|
0.00617
|
|
100
|
Trifluoroethanol
|
Compound
|
Inferred
|
Explain
|
0.00558
|
|