Factor VII Deficiency

Disease • C0015503

Definition

An autosomal recessive characteristic or a coagulation disorder acquired in association with VITAMIN K DEFICIENCY. FACTOR VII is a Vitamin K dependent glycoprotein essential to the extrinsic pathway of coagulation.

Synonyms

Factor VII Deficiency • Deficiency, factor VII • Deficiencies, Factor VII • Factor VII Deficiencies • Hypoproconvertinemia • SERUM PROTHROMBIN CONVERSION ACCELERATOR DEFICIENCY • STABLE FACTOR DEFICIENCY • PROCONVERTIN DEFICIENCY • SPCA DEFICIENCY • Hypoproconvertinemias • Deficiency, stable • DEFIC FACTOR VII • FACTOR VII DEFIC • Factor VII Deficiency [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

F7 gene    Hemorrhagic Disorders    Blood Coagulation Disorders, Inherited    Coagulation Protein Disorders   

Related concepts

# Concept name Type Relation Support Score
1 Coagulation Protein Disorders Disease Known Explain 116.51486
2 Blood Coagulation Disorders, Inherited Disease Known Explain 87.04012
3 Hemorrhagic Disorders Disease Known Explain 79.91175
4 F7 gene Gene Known Explain 35.68988
5 Hypoprothrombinemias Disease Inferred Explain 3.45614
6 Factor V Deficiency Disease Inferred Explain 3.44148
7 Factor X Deficiency Disease Inferred Explain 3.42970
8 Factor XI Deficiency Disease Inferred Explain 3.39786
9 Factor XII Deficiency Disease Inferred Explain 3.34903
10 Factor XIII Deficiency Disease Inferred Explain 3.18351
11 Hemophilia B Disease Inferred Explain 3.08507
12 Afibrinogenemia Disease Inferred Explain 3.05378
13 Hemophilia A Disease Inferred Explain 2.71015
14 von Willebrand Disease Disease Inferred Explain 2.34974
15 Activated Protein C Resistance Disease Inferred Explain 2.14493
16 Blood Coagulation Disorders Disease Inferred Explain 1.29687
17 Thrombasthenia Disease Inferred Explain 1.00457
18 Wiskott-Aldrich Syndrome Disease Inferred Explain 0.91763
19 Hermanski-Pudlak Syndrome Disease Inferred Explain 0.85749
20 Bernard-Soulier Syndrome Disease Inferred Explain 0.79256
21 Blood Platelet Disorders Disease Inferred Explain 0.64774
22 Platelet Storage Pool Deficiency Disease Inferred Explain 0.50162
23 Gray Platelet Syndrome Disease Inferred Explain 0.41933
24 Disseminated Intravascular Coagulation Disease Inferred Explain 0.40223
25 Thrombophilia Disease Inferred Explain 0.35671
26 Antithrombin III Deficiency Disease Inferred Explain 0.34496
27 Thrombocythemia, Essential Disease Inferred Explain 0.34250
28 Protein C Deficiency Disease Inferred Explain 0.32832
29 Vitamin K Deficiency Disease Inferred Explain 0.32510
30 F9 gene Gene Inferred Explain 0.28186
31 Waterhouse-Friderichsen Syndrome Disease Inferred Explain 0.25154
32 Purpura, Thrombocytopenic, Idiopathic Disease Inferred Explain 0.21965
33 F13B gene Gene Inferred Explain 0.18752
34 F10 gene Gene Inferred Explain 0.18048
35 Hereditary factor I deficiency disease Disease Inferred Explain 0.17857
36 F11 gene Gene Inferred Explain 0.17221
37 Hematological Disease Disease Inferred Explain 0.16086
38 F5 gene Gene Inferred Explain 0.13709
39 Genetic Diseases, X-Linked Disease Inferred Explain 0.12745
40 Vascular Hemostatic Disorders Disease Inferred Explain 0.11709
41 FGA gene Gene Inferred Explain 0.11111
42 F12 gene Gene Inferred Explain 0.10793
43 FGB gene Gene Inferred Explain 0.10721
44 F13A1 gene Gene Inferred Explain 0.09455
45 CFI gene Gene Inferred Explain 0.07948
46 F2 gene Gene Inferred Explain 0.07698
47 PROC gene Gene Inferred Explain 0.07593
48 P2RX1 gene Gene Inferred Explain 0.06038
49 Lymphopenia Disease Inferred Explain 0.05780
50 Blood Protein Disorders Disease Inferred Explain 0.05707
51 Genetic Diseases, Inborn Disease Inferred Explain 0.04416
52 Malnutrition Disease Inferred Explain 0.04330
53 GGCX gene Gene Inferred Explain 0.04058
54 MTHFR gene Gene Inferred Explain 0.04043
55 GIANT PLATELET SYNDROME WITH THROMBOCYTOPENIA Disease Inferred Explain 0.03993
56 Protein S Deficiency Disease Inferred Explain 0.03878
57 HEMOPHILIA A WITH VASCULAR ABNORMALITY Disease Inferred Explain 0.03714
58 VWF gene Gene Inferred Explain 0.03651
59 Thrombocytosis Disease Inferred Explain 0.03524
60 Warfarin Compound Inferred Explain 0.03288
61 blood coagulation, extrinsic pathway Function Inferred Explain 0.03076
62 Purpura Disease Inferred Explain 0.03073
63 Blood Platelets Other Inferred Explain 0.02969
64 von Willebrand Disease, Type 3 Disease Inferred Explain 0.02875
65 VON WILLEBRAND DISEASE, X-LINKED FORM Disease Inferred Explain 0.02875
66 Von Willebrand disease, platelet type Disease Inferred Explain 0.02809
67 Gestodene Compound Inferred Explain 0.02771
68 response to vitamin K Function Inferred Explain 0.02763
69 von Willebrand Disease, Recessive Form Disease Inferred Explain 0.02739
70 CycloProvera Compound Inferred Explain 0.02713
71 Mesigyna Compound Inferred Explain 0.02713
72 GP1BA gene Gene Inferred Explain 0.02679
73 GP9 gene Gene Inferred Explain 0.02605
74 Immunologic Deficiency Syndromes Disease Inferred Explain 0.02505
75 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one Compound Inferred Explain 0.02415
76 F8 gene Gene Inferred Explain 0.02389
77 estradiol valerate-dienogest Compound Inferred Explain 0.02224
78 SERPINC1 gene Gene Inferred Explain 0.02201
79 NuvaRing Compound Inferred Explain 0.02196
80 Mercilon Compound Inferred Explain 0.02186
81 peptidyl-glutamic acid carboxylation Function Inferred Explain 0.02158
82 positive regulation of platelet-derived growth factor receptor signaling pathway Function Inferred Explain 0.02110
83 GP1BB gene Gene Inferred Explain 0.02069
84 ITGA2B gene Gene Inferred Explain 0.01802
85 dienogest Compound Inferred Explain 0.01759
86 propylene dichloride Compound Inferred Explain 0.01685
87 positive regulation of blood coagulation Function Inferred Explain 0.01617
88 Norethindrone Compound Inferred Explain 0.01591
89 Complement and coagulation cascades - Homo sapiens (human) Pathway Inferred Explain 0.01565
90 norgestimate Compound Inferred Explain 0.01431
91 response to growth hormone stimulus Function Inferred Explain 0.01412
92 Thrombocytopenia Disease Inferred Explain 0.01408
93 vesicular fraction Component Inferred Explain 0.01386
94 Golgi lumen Component Inferred Explain 0.01341
95 F3 gene Gene Inferred Explain 0.01305
96 Ethionine Compound Inferred Explain 0.01291
97 positive regulation of positive chemotaxis Function Inferred Explain 0.01272
98 Ecchymosis Disease Inferred Explain 0.01110
99 antibiotic G 418 Compound Inferred Explain 0.01077
100 Estrogens, Conjugated (USP) Compound Inferred Explain 0.01052