Doxorubicin

Compound • C0013089

Definition

An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline.

Synonyms

Doxorubicin • ADM • 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)- • (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione • ADR • Hydroxyl Daunorubicin • DOX • (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione • 14-Hydroxydaunomycin • Hydroxyldaunorubicin • Doxorubicin [Chemical/Ingredient]

Linked items?Related concepts, ordered by their global importance in the network.

ESR1 gene    TP53 gene    MAPK1 gene    MYC gene    TNF gene    EGFR gene    BCL2 gene    ESR2 gene    RELA gene    CASP3 gene    MAPK3 gene    AKT1 gene    MAPK14 gene    GSK3B gene    JUN gene    CYP1A1 gene    CYP1A2 gene    CDK2 gene    Prostatic Neoplasms    PRKCA gene   

Related concepts

# Concept name Type Relation Support Score
1 Vinblastine Compound Inferred Explain 0.01148
2 OR10B1P gene Gene Known Explain 0.00766
3 HIST2H3PS2 gene Gene Known Explain 0.00743
4 DENND2A gene Gene Known Explain 0.00700
5 CRISP2 gene Gene Known Explain 0.00645
6 SCUBE2 gene Gene Known Explain 0.00637
7 Phyllodes Tumor Disease Known Explain 0.00608
8 Endomyocardial Fibrosis Disease Known Explain 0.00605
9 NUDT15 gene Gene Known Explain 0.00600
10 HIST2H4B gene Gene Known Explain 0.00599
11 EFCAB7 gene Gene Known Explain 0.00598
12 TSPAN13 gene Gene Known Explain 0.00582
13 TMEM134 gene Gene Known Explain 0.00581
14 FAM69A gene Gene Known Explain 0.00576
15 Acute Erythroblastic Leukemia Disease Known Explain 0.00539
16 KIAA1467 gene Gene Known Explain 0.00536
17 DLEU2 gene Gene Known Explain 0.00525
18 FRMD4A gene Gene Known Explain 0.00518
19 TMEM156 gene Gene Known Explain 0.00517
20 BBS12 gene Gene Known Explain 0.00509
21 TMEM14A gene Gene Known Explain 0.00505
22 CABC1 gene Gene Known Explain 0.00504
23 DONSON gene Gene Known Explain 0.00499
24 Protein Binding Function Inferred Explain 0.00498
25 NKAIN1 gene Gene Known Explain 0.00497
26 BCL2L12 gene Gene Known Explain 0.00495
27 Fluorouracil Compound Inferred Explain 0.00494
28 Ewings sarcoma Disease Known Explain 0.00485
29 OR12D2 gene Gene Known Explain 0.00481
30 GPR176 gene Gene Known Explain 0.00477
31 SNRNP25 gene Gene Known Explain 0.00477
32 ZDHHC11 gene Gene Known Explain 0.00472
33 TRIM34 gene Gene Known Explain 0.00462
34 7-epi-Taxol Compound Inferred Explain 0.00459
35 Fibromatosis, Aggressive Disease Known Explain 0.00458
36 Soft Tissue Neoplasms Disease Known Explain 0.00455
37 RFTN1 gene Gene Known Explain 0.00454
38 Bone Marrow Neoplasms Disease Known Explain 0.00453
39 CAPN6 gene Gene Known Explain 0.00450
40 Cyclosporine Compound Inferred Explain 0.00444
41 Carcinoid Tumor Disease Known Explain 0.00444
42 ZNF552 gene Gene Known Explain 0.00441
43 Mucositis Disease Known Explain 0.00441
44 EPYC gene Gene Known Explain 0.00439
45 MRPS18A gene Gene Known Explain 0.00437
46 MICAL2 gene Gene Known Explain 0.00437
47 T-Cell Lymphoma Disease Known Explain 0.00435
48 ARHGEF17 gene Gene Known Explain 0.00434
49 KCNJ13 gene Gene Known Explain 0.00424
50 PSG4 gene Gene Known Explain 0.00421
51 Sarcoma, Epithelioid Disease Known Explain 0.00418
52 OR2F1 gene Gene Known Explain 0.00418
53 OR1I1 gene Gene Known Explain 0.00416
54 PSG6 gene Gene Known Explain 0.00414
55 Nephrosis Disease Known Explain 0.00413
56 SNX10 gene Gene Known Explain 0.00407
57 DKK2 gene Gene Known Explain 0.00401
58 Pleural Neoplasms Disease Known Explain 0.00400
59 osteosarcoma Disease Known Explain 0.00392
60 RAB6C gene Gene Known Explain 0.00391
61 PITPNC1 gene Gene Known Explain 0.00390
62 CIAPIN1 gene Gene Known Explain 0.00386
63 Cytoplasm Component Inferred Explain 0.00379
64 BNC1 gene Gene Known Explain 0.00377
65 Cell Nucleus Component Inferred Explain 0.00377
66 RNF19B gene Gene Known Explain 0.00375
67 THNSL2 gene Gene Known Explain 0.00370
68 Epirubicin Compound Known Explain 0.00368
69 METRN gene Gene Known Explain 0.00367
70 ZNF22 gene Gene Known Explain 0.00366
71 Estradiol Compound Inferred Explain 0.00364
72 RAB11FIP1 gene Gene Known Explain 0.00362
73 Kaposi Sarcoma Disease Known Explain 0.00361
74 SYDE1 gene Gene Known Explain 0.00359
75 CRHBP gene Gene Known Explain 0.00357
76 Ventricular Dysfunction, Left Disease Known Explain 0.00351
77 CKAP2 gene Gene Known Explain 0.00351
78 FAIM2 gene Gene Known Explain 0.00343
79 ORC6L gene Gene Known Explain 0.00339
80 ADAMTS5 gene Gene Known Explain 0.00336
81 Benzo(a)pyrene Compound Inferred Explain 0.00334
82 PTCD3 gene Gene Known Explain 0.00330
83 APOBEC3C gene Gene Known Explain 0.00326
84 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Compound Inferred Explain 0.00326
85 API5 gene Gene Known Explain 0.00325
86 Reticulosarcoma Disease Known Explain 0.00322
87 HMGN3 gene Gene Known Explain 0.00320
88 RGS13 gene Gene Known Explain 0.00318
89 KCNJ16 gene Gene Known Explain 0.00317
90 HCRTR1 gene Gene Known Explain 0.00317
91 Kidney Failure Disease Known Explain 0.00316
92 Hemangiosarcoma Disease Known Explain 0.00315
93 GP9 gene Gene Known Explain 0.00315
94 HIST1H1E gene Gene Known Explain 0.00313
95 BTG3 gene Gene Known Explain 0.00312
96 GTSE1 gene Gene Known Explain 0.00310
97 DZIP1 gene Gene Known Explain 0.00309
98 CPXM1 gene Gene Known Explain 0.00308
99 PROCR gene Gene Known Explain 0.00307
100 Nephrotic Syndrome Disease Known Explain 0.00306