Diabetic Nephropathy

Disease • C0011881

Definition

Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis.

Synonyms

Diabetic Nephropathy • Diabetic Nephropathies • Nephropathies, Diabetic • Nephropathy, Diabetic • Diabetes with renal manifestations • Diabetic Kidney Disease • Diabetic Kidney Diseases • Kidney Diseases, Diabetic • Kidney Disease, Diabetic • Diabetic Kidney Problems • Diabetic Nephropathies [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

Estradiol    resveratrol    Tamoxifen    Raloxifene    Curcumin    TGFB1 gene    VEGFA gene    Plant Extracts    KDR gene    Kidney Diseases    ACE gene    valsartan    GAS6 gene    TXNIP gene    AXL gene    Warfarin    mangiferin    Streptozocin    Complications of Diabetes Mellitus    Perindopril   

Related concepts

# Concept name Type Relation Support Score
1 Perindopril Compound Known Explain 7.07495
2 Complications of Diabetes Mellitus Disease Known Explain 4.50184
3 Streptozocin Compound Known Explain 3.77955
4 AXL gene Gene Known Explain 2.07436
5 TXNIP gene Gene Known Explain 1.73401
6 GAS6 gene Gene Known Explain 1.64753
7 mangiferin Compound Known Explain 1.53930
8 Warfarin Compound Known Explain 1.36557
9 valsartan Compound Known Explain 1.32590
10 ACE gene Gene Known Explain 1.04752
11 KDR gene Gene Known Explain 0.95598
12 Kidney Diseases Disease Known Explain 0.65089
13 Plant Extracts Compound Known Explain 0.48892
14 VEGFA gene Gene Known Explain 0.38003
15 TGFB1 gene Gene Known Explain 0.29218
16 Toxic effect of carbon tetrachloride Other Inferred Explain 0.25470
17 Raloxifene Compound Known Explain 0.24408
18 Curcumin Compound Known Explain 0.23929
19 resveratrol Compound Known Explain 0.20715
20 Tamoxifen Compound Known Explain 0.20310
21 Indoles Compound Inferred Explain 0.13234
22 Estradiol Compound Known Explain 0.07502
23 Hypertensive disease Disease Inferred Explain 0.06567
24 Fetal Macrosomia Disease Inferred Explain 0.05663
25 Diabetic Ketoacidosis Disease Inferred Explain 0.05028
26 protocatechualdehyde Compound Inferred Explain 0.04246
27 Diabetic Angiopathies Disease Inferred Explain 0.04016
28 Liver Cirrhosis, Experimental Disease Inferred Explain 0.03963
29 Diabetic Neuropathies Disease Inferred Explain 0.03336
30 Diabetes Mellitus Disease Inferred Explain 0.03064
31 bivalirudin Compound Inferred Explain 0.02198
32 Diabetic Retinopathy Disease Inferred Explain 0.02173
33 Diabetic Cardiomyopathies Disease Inferred Explain 0.01960
34 Alloxan Diabetes Disease Inferred Explain 0.01453
35 Carcinoid Tumor Disease Inferred Explain 0.01408
36 Aminoglycosides Compound Inferred Explain 0.01219
37 Nitrosourea Compounds Compound Inferred Explain 0.01091
38 Ketosis Disease Inferred Explain 0.01027
39 Diabetes Mellitus, Insulin-Dependent Disease Inferred Explain 0.00711
40 Heart Diseases Disease Inferred Explain 0.00652
41 Birth Weight Other Inferred Explain 0.00610
42 Pregnancy in Diabetics Disease Inferred Explain 0.00521
43 Diabetes Mellitus, Non-Insulin-Dependent Disease Inferred Explain 0.00495
44 Gestational Diabetes Disease Inferred Explain 0.00487
45 Thrombosis Disease Inferred Explain 0.00416
46 Thromboembolism Disease Inferred Explain 0.00365
47 Venous Thromboembolism Disease Inferred Explain 0.00302
48 Diabetic Foot Disease Inferred Explain 0.00294
49 Gaucher Disease Disease Inferred Explain 0.00261
50 Protein Binding Function Inferred Explain 0.00260
51 Trichinellosis Disease Inferred Explain 0.00254
52 Fetal Diseases Disease Inferred Explain 0.00238
53 Cerebrovascular accident Disease Inferred Explain 0.00219
54 Body Weight Other Inferred Explain 0.00214
55 Cyclosporine Compound Inferred Explain 0.00213
56 MGMT gene Gene Inferred Explain 0.00213
57 Anuria Disease Inferred Explain 0.00204
58 AGTR2 gene Gene Inferred Explain 0.00201
59 Tetrachlorodibenzodioxin Compound Inferred Explain 0.00198
60 Ischemia Disease Inferred Explain 0.00185
61 Cell Nucleus Component Inferred Explain 0.00181
62 4-Hydroxycoumarins Compound Inferred Explain 0.00179
63 Cytoplasm Component Inferred Explain 0.00176
64 Pericementitis Disease Inferred Explain 0.00175
65 20-alpha-Dihydroprogesterone Compound Inferred Explain 0.00164
66 Sinus Thrombosis, Intracranial Disease Inferred Explain 0.00163
67 PTGS2 gene Gene Inferred Explain 0.00162
68 Hematoma Disease Inferred Explain 0.00161
69 Cardiomegaly Disease Inferred Explain 0.00159
70 Ayerza Syndrome Disease Inferred Explain 0.00159
71 Benzo(a)pyrene Compound Inferred Explain 0.00157
72 TNF gene Gene Inferred Explain 0.00155
73 anaphylaxis Disease Inferred Explain 0.00154
74 PROC gene Gene Inferred Explain 0.00154
75 COUMARIN RESISTANCE Disease Inferred Explain 0.00152
76 Radiation Injuries, Experimental Other Inferred Explain 0.00152
77 Thrombophilia Disease Inferred Explain 0.00151
78 Protein C Deficiency Disease Inferred Explain 0.00150
79 Coronary Arteriosclerosis Disease Inferred Explain 0.00150
80 Pregnanolone Compound Inferred Explain 0.00149
81 Myocardial Infarction Disease Inferred Explain 0.00142
82 Cell membrane Component Inferred Explain 0.00142
83 Pulmonary Embolism Disease Inferred Explain 0.00141
84 Doxorubicin Compound Inferred Explain 0.00139
85 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Compound Inferred Explain 0.00139
86 F2 gene Gene Inferred Explain 0.00138
87 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid Compound Inferred Explain 0.00137
88 Coronary Restenosis Disease Inferred Explain 0.00136
89 Progesterone Compound Inferred Explain 0.00135
90 Hemorrhage Disease Inferred Explain 0.00135
91 Fatty Liver Disease Inferred Explain 0.00135
92 Endotoxic shock Disease Inferred Explain 0.00133
93 Malignant Hypertension Disease Inferred Explain 0.00133
94 MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 1(finding) Disease Inferred Explain 0.00131
95 Venous Thrombosis Disease Inferred Explain 0.00131
96 Cardiovascular Diseases Disease Inferred Explain 0.00130
97 Pregnancy Complications Disease Inferred Explain 0.00129
98 Gastrointestinal Hemorrhage Disease Inferred Explain 0.00128
99 Indomethacin Compound Inferred Explain 0.00124
100 TP53 gene Gene Inferred Explain 0.00123