Cell Transformation, Neoplastic

Disease • C0007621

Definition

Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade

Synonyms

Cell Transformation, Neoplastic • neoplastic cell transformation • Cell Neoplastic Transformations • Cell Transformations, Neoplastic • Neoplastic Cell Transformations • Neoplastic Transformations, Cell • Transformations, Cell Neoplastic • Transformations, Neoplastic Cell • Cell Neoplastic Transformation • Neoplastic Transformation, Cell • Transformation, Cell Neoplastic • Transformation, Neoplastic Cell • neoplastic transformation • CELL TRANSFORM NEOPL • NEOPL CELL TRANSFORM • NEOPL TRANSFORM CELL • TRANSFORM NEOPL CELL

Linked items?Related concepts, ordered by their global importance in the network.

Estradiol    sodium arsenite    MMP9 gene    tobacco tar    Acetylcysteine    TSC22D1 gene    Cadmium    MMA(III)    WNT5A gene    SLC2A1 gene    AKR1C1 gene    Dinoprostone    AKR1C3 gene    POR gene    AKR1C2 gene    SLC16A1 gene    LGALS3 gene    20-Methylcholanthrene    4-biphenylamine    Ethylnitrosourea   

Related concepts

# Concept name Type Relation Support Score
1 Blast Phase Disease Known Explain 26.14971
2 Cell Transformation, Viral Function Known Explain 21.29309
3 bromoform Compound Known Explain 10.72030
4 Azoxymethane Compound Known Explain 8.88053
5 Neoplastic Processes Disease Known Explain 7.96112
6 Dinoprost Compound Known Explain 4.02340
7 4-hydroxyestradiol-17 alpha Compound Known Explain 3.26000
8 Ethylnitrosourea Compound Known Explain 2.55547
9 4-biphenylamine Compound Known Explain 2.12327
10 20-Methylcholanthrene Compound Known Explain 2.08954
11 LGALS3 gene Gene Known Explain 1.13613
12 AKR1C3 gene Gene Known Explain 1.08894
13 AKR1C2 gene Gene Known Explain 1.08864
14 SLC16A1 gene Gene Known Explain 1.04089
15 POR gene Gene Known Explain 0.99568
16 AKR1C1 gene Gene Known Explain 0.98381
17 Virus Physiological Processes Other Inferred Explain 0.97231
18 Dinoprostone Compound Known Explain 0.85941
19 SLC2A1 gene Gene Known Explain 0.61957
20 WNT5A gene Gene Known Explain 0.54552
21 MMA(III) Compound Known Explain 0.51048
22 Cadmium Compound Known Explain 0.48425
23 TSC22D1 gene Gene Known Explain 0.46688
24 Acetylcysteine Compound Known Explain 0.37888
25 tobacco tar Compound Known Explain 0.37225
26 MMP9 gene Gene Known Explain 0.34424
27 Neoplasm Regression, Spontaneous Function Inferred Explain 0.34378
28 Myeloid Leukemia, Chronic Disease Inferred Explain 0.27492
29 Rectal Carcinoma Disease Inferred Explain 0.12549
30 Azo Compounds Compound Inferred Explain 0.11926
31 sodium arsenite Compound Known Explain 0.09316
32 Precancerous Conditions Disease Inferred Explain 0.07384
33 Prostaglandins F Compound Inferred Explain 0.06914
34 Neoplasms Disease Inferred Explain 0.06152
35 Estradiol Compound Known Explain 0.06126
36 Neoplasm Invasiveness Disease Inferred Explain 0.05995
37 Hemagglutination, Viral Other Inferred Explain 0.05010
38 Virus Replication Function Inferred Explain 0.04537
39 Antibody-Dependent Enhancement Disease Inferred Explain 0.03904
40 Remission, Spontaneous Other Inferred Explain 0.03798
41 GABRB2 gene Gene Inferred Explain 0.03594
42 Virus Integration Function Inferred Explain 0.03308
43 GABRA1 gene Gene Inferred Explain 0.03179
44 GABRG2 gene Gene Inferred Explain 0.03037
45 N-(4-chlorobenzoyl)melatonin Compound Inferred Explain 0.02810
46 Virus Inactivation Other Inferred Explain 0.02774
47 oligodendroglioma Disease Inferred Explain 0.02333
48 Pathologic Processes Disease Inferred Explain 0.02329
49 Neoplasm Metastasis Disease Inferred Explain 0.02147
50 trans-1,2-Dihydrobenzene-1,2-diol Compound Inferred Explain 0.01803
51 Microbiological Processes Other Inferred Explain 0.01800
52 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Function Inferred Explain 0.01770
53 Lung Neoplasms Disease Inferred Explain 0.01757
54 9,10-phenanthrenequinone Compound Inferred Explain 0.01733
55 Central Nervous System Neoplasms Disease Inferred Explain 0.01714
56 Neoplasm Recurrence, Local Disease Inferred Explain 0.01677
57 Virus Physiological Phenomena Other Inferred Explain 0.01625
58 7-hydroxyflavone Compound Inferred Explain 0.01564
59 Chromosomal Instability Disease Inferred Explain 0.01507
60 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity Function Inferred Explain 0.01491
61 meningioma Disease Inferred Explain 0.01486
62 5alpha-Androstane-3,17-dione Compound Inferred Explain 0.01474
63 Thymus Neoplasms Disease Inferred Explain 0.01326
64 Catechol Compound Inferred Explain 0.01320
65 Malignant tumor of colon Disease Inferred Explain 0.01296
66 Neurilemmoma Disease Inferred Explain 0.01203
67 indanol dehydrogenase activity Function Inferred Explain 0.01187
68 Carcinoma of the Large Intestine Disease Inferred Explain 0.01136
69 Fever Disease Inferred Explain 0.01131
70 CBR3 gene Gene Inferred Explain 0.01085
71 Nitrosourea Compounds Compound Inferred Explain 0.00961
72 T-Cell Lymphoma Disease Inferred Explain 0.00932
73 Hemagglutination Function Inferred Explain 0.00863
74 Ectodermal Dysplasia Disease Inferred Explain 0.00740
75 6-Ketoprostaglandin F1 alpha Compound Inferred Explain 0.00705
76 fibrosarcoma Disease Inferred Explain 0.00689
77 HPGD gene Gene Inferred Explain 0.00680
78 SLC22A7 gene Gene Inferred Explain 0.00668
79 CBR1 gene Gene Inferred Explain 0.00619
80 HSD11B2 gene Gene Inferred Explain 0.00602
81 mevalonate transport Function Inferred Explain 0.00589
82 mevalonate transmembrane transporter activity Function Inferred Explain 0.00583
83 CD59 gene Gene Inferred Explain 0.00575
84 HYPERINSULINEMIC HYPOGLYCEMIA, FAMILIAL, 7 Disease Inferred Explain 0.00572
85 naringenin Compound Inferred Explain 0.00571
86 GG 745 Compound Inferred Explain 0.00548
87 Neoplasms, Experimental Disease Inferred Explain 0.00539
88 5-nitro-2-(3-phenylpropylamino)benzoic acid Compound Inferred Explain 0.00532
89 ametryne Compound Inferred Explain 0.00501
90 RH1 benzoquinone Compound Inferred Explain 0.00498
91 prostaglandin-F synthase activity Function Inferred Explain 0.00498
92 pseudohypericin Compound Inferred Explain 0.00497
93 NSC 130181 Compound Inferred Explain 0.00496
94 bile acid binding Function Inferred Explain 0.00496
95 ALPPL2 gene Gene Inferred Explain 0.00490
96 Brain Neoplasms Disease Inferred Explain 0.00477
97 ATP2B4 gene Gene Inferred Explain 0.00470
98 Clubbed Fingers Other Inferred Explain 0.00456
99 NADPH-ferrihemoprotein reductase activity Function Inferred Explain 0.00448
100 prostaglandin metabolic process Function Inferred Explain 0.00432