Estrogens, Catechol
Compound • C0007406
Definition2- or 4-Hydroxyestrogens. Substances that are physiologically active in mammals, especially in the control of gonadotropin secretion. Physiological activity can be ascribed to either an estrogenic action or interaction with the catecholaminergic system. SynonymsEstrogens, Catechol • Catechol estrogens • Catecholestrogens |
Linked items?Related concepts, ordered by their global importance in the network. |
Related concepts
# | Concept name | Type | Relation | Support | Score |
---|---|---|---|---|---|
1 | Hydroxyestrones | Compound | Known | Explain | 82.82879 |
2 | Catechols | Compound | Known | Explain | 24.59541 |
3 | Estradiol Congeners | Compound | Known | Explain | 22.18767 |
4 | Endometrial Neoplasms | Disease | Known | Explain | 5.60683 |
5 | CYP17A1 gene | Gene | Known | Explain | 2.19691 |
6 | SULT1A1 gene | Gene | Known | Explain | 1.87562 |
7 | COMT gene | Gene | Known | Explain | 1.75439 |
8 | GSTT1 gene | Gene | Known | Explain | 1.54191 |
9 | GSTM1 gene | Gene | Known | Explain | 1.13767 |
10 | UGT1A1 gene | Gene | Known | Explain | 0.88525 |
11 | Estrogenic Steroids, Alkylated | Compound | Inferred | Explain | 0.70104 |
12 | Malignant neoplasm of breast | Disease | Known | Explain | 0.59836 |
13 | Equilenin | Compound | Inferred | Explain | 0.54895 |
14 | Equilin | Compound | Inferred | Explain | 0.54895 |
15 | Estrone | Compound | Inferred | Explain | 0.54748 |
16 | CYP1A1 gene | Gene | Known | Explain | 0.47288 |
17 | Prostatic Neoplasms | Disease | Known | Explain | 0.40698 |
18 | Guaiacol | Compound | Inferred | Explain | 0.38565 |
19 | MAPK3 gene | Gene | Known | Explain | 0.35883 |
20 | MAPK1 gene | Gene | Known | Explain | 0.31616 |
21 | Gonadal Steroid Hormones | Compound | Inferred | Explain | 0.25716 |
22 | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt | Compound | Inferred | Explain | 0.17164 |
23 | Phenols | Compound | Inferred | Explain | 0.13571 |
24 | Estrogens, Conjugated (USP) | Compound | Inferred | Explain | 0.08510 |
25 | Nordihydroguaiaretic Acid | Compound | Inferred | Explain | 0.07163 |
26 | 17-Ketosteroids | Compound | Inferred | Explain | 0.06436 |
27 | Endometrial Stromal Tumors | Disease | Inferred | Explain | 0.05814 |
28 | bu-zhong-yi-qi-tang | Other | Inferred | Explain | 0.04932 |
29 | STX64 compound | Compound | Inferred | Explain | 0.04892 |
30 | STX 213 | Compound | Inferred | Explain | 0.04892 |
31 | Estriol | Compound | Inferred | Explain | 0.04241 |
32 | Estrenes | Compound | Inferred | Explain | 0.04118 |
33 | Carcinoma, Endometrioid | Disease | Inferred | Explain | 0.03256 |
34 | Capsaicin | Compound | Inferred | Explain | 0.02751 |
35 | Guaifenesin | Compound | Inferred | Explain | 0.01914 |
36 | Ethylenethiourea | Compound | Inferred | Explain | 0.01345 |
37 | 2-methoxyestradiol-3,17-O,O-bis(sulfamate) | Compound | Inferred | Explain | 0.01281 |
38 | nitrobenzene | Compound | Inferred | Explain | 0.01280 |
39 | 2,2',3,4,4',5',6-heptabromodiphenyl ether | Compound | Inferred | Explain | 0.01252 |
40 | Phenyl Ethers | Compound | Inferred | Explain | 0.01120 |
41 | Deficiency of steroid 17-alpha-monooxygenase | Disease | Inferred | Explain | 0.01037 |
42 | Sodium Nitrite | Compound | Inferred | Explain | 0.00957 |
43 | Methyl Ethers | Compound | Inferred | Explain | 0.00925 |
44 | kahweol | Compound | Inferred | Explain | 0.00888 |
45 | cafestol | Compound | Inferred | Explain | 0.00888 |
46 | Progesterone Congeners | Compound | Inferred | Explain | 0.00848 |
47 | Phytoestrogens | Compound | Inferred | Explain | 0.00822 |
48 | Curcumin | Compound | Inferred | Explain | 0.00787 |
49 | 17alpha,20alpha-Dihydroxycholesterol | Compound | Inferred | Explain | 0.00757 |
50 | 20alpha-Hydroxycholesterol | Compound | Inferred | Explain | 0.00757 |
51 | Uterine Neoplasms | Disease | Inferred | Explain | 0.00748 |
52 | 7-methylguanine | Compound | Inferred | Explain | 0.00731 |
53 | SULT1A3 gene | Gene | Inferred | Explain | 0.00709 |
54 | Estradiol | Compound | Inferred | Explain | 0.00653 |
55 | Pyrogallol | Compound | Inferred | Explain | 0.00634 |
56 | Diiodothyronines | Compound | Inferred | Explain | 0.00626 |
57 | Chlorophenols | Compound | Inferred | Explain | 0.00613 |
58 | Hydroxyprogesterone | Compound | Inferred | Explain | 0.00612 |
59 | JAZF1 gene | Gene | Inferred | Explain | 0.00596 |
60 | 3,3'-diiodothyronine | Compound | Inferred | Explain | 0.00589 |
61 | 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine | Compound | Inferred | Explain | 0.00589 |
62 | 6-hydroxymelatonin | Compound | Inferred | Explain | 0.00589 |
63 | 5-hydroxyindole | Compound | Inferred | Explain | 0.00589 |
64 | harmol | Compound | Inferred | Explain | 0.00589 |
65 | Endometrial Stromal Sarcoma | Disease | Inferred | Explain | 0.00578 |
66 | 3-hydroxybenzo(a)pyrene | Compound | Inferred | Explain | 0.00555 |
67 | 2-methoxyestradiol | Compound | Inferred | Explain | 0.00547 |
68 | N-nitrosodiethanolamine | Compound | Inferred | Explain | 0.00528 |
69 | Benserazide | Compound | Inferred | Explain | 0.00515 |
70 | 2-hydroxyestradiol | Compound | Inferred | Explain | 0.00513 |
71 | steroid 17-alpha-hydroxylase-C17-20 lyase activity | Function | Inferred | Explain | 0.00507 |
72 | O-methyltransferase, family 3 | Domain | Inferred | Explain | 0.00501 |
73 | PANIC DISORDER 1 | Disease | Inferred | Explain | 0.00494 |
74 | SK&F-38393 | Inferred | Explain | 0.00493 | |
75 | Halogenated Diphenyl Ethers | Compound | Inferred | Explain | 0.00476 |
76 | Fenofibrate | Compound | Inferred | Explain | 0.00473 |
77 | 4-methylcatechol | Compound | Inferred | Explain | 0.00460 |
78 | Catechol O-methyltransferase, eukaryotic | Domain | Inferred | Explain | 0.00458 |
79 | GSTA1 gene | Gene | Inferred | Explain | 0.00455 |
80 | Ethinyl Estradiol | Compound | Inferred | Explain | 0.00443 |
81 | Methyldopa | Compound | Inferred | Explain | 0.00433 |
82 | 15-A(2t)-IsoP | Compound | Inferred | Explain | 0.00428 |
83 | pinocembrin | Compound | Inferred | Explain | 0.00426 |
84 | UGT1A9 gene | Gene | Inferred | Explain | 0.00425 |
85 | Pregnanolone | Compound | Inferred | Explain | 0.00424 |
86 | Raynaud Disease | Disease | Inferred | Explain | 0.00420 |
87 | Steroid | Compound | Inferred | Explain | 0.00414 |
88 | 11beta-Hydroxyprogesterone | Compound | Inferred | Explain | 0.00414 |
89 | 21-Deoxycortisol | Compound | Inferred | Explain | 0.00414 |
90 | Sodium, Dietary | Compound | Inferred | Explain | 0.00408 |
91 | Gonadal Hormones | Compound | Inferred | Explain | 0.00402 |
92 | Hydroxytryptophol | Compound | Inferred | Explain | 0.00400 |
93 | CS 045 | Compound | Inferred | Explain | 0.00398 |
94 | Testosterone Congeners | Compound | Inferred | Explain | 0.00398 |
95 | Androsterone | Compound | Inferred | Explain | 0.00395 |
96 | tetrabrominated diphenyl ether 47 | Compound | Inferred | Explain | 0.00392 |
97 | 4-methylumbelliferone | Compound | Inferred | Explain | 0.00392 |
98 | 1,2-epoxy-3-(p-nitrophenoxy)propane | Compound | Inferred | Explain | 0.00390 |
99 | drospirenone | Compound | Inferred | Explain | 0.00387 |
100 | caffeic acid | Compound | Inferred | Explain | 0.00384 |