Estrogens, Catechol

Compound • C0007406

Definition

2- or 4-Hydroxyestrogens. Substances that are physiologically active in mammals, especially in the control of gonadotropin secretion. Physiological activity can be ascribed to either an estrogenic action or interaction with the catecholaminergic system.

Synonyms

Estrogens, Catechol • Catechol estrogens • Catecholestrogens

Linked items?Related concepts, ordered by their global importance in the network.

MAPK1 gene    MAPK3 gene    Prostatic Neoplasms    CYP1A1 gene    Malignant neoplasm of breast    UGT1A1 gene    GSTM1 gene    GSTT1 gene    COMT gene    SULT1A1 gene    CYP17A1 gene    Endometrial Neoplasms    Estradiol Congeners    Catechols    Hydroxyestrones   

Related concepts

# Concept name Type Relation Support Score
1 Hydroxyestrones Compound Known Explain 82.82879
2 Catechols Compound Known Explain 24.59541
3 Estradiol Congeners Compound Known Explain 22.18767
4 Endometrial Neoplasms Disease Known Explain 5.60683
5 CYP17A1 gene Gene Known Explain 2.19691
6 SULT1A1 gene Gene Known Explain 1.87562
7 COMT gene Gene Known Explain 1.75439
8 GSTT1 gene Gene Known Explain 1.54191
9 GSTM1 gene Gene Known Explain 1.13767
10 UGT1A1 gene Gene Known Explain 0.88525
11 Estrogenic Steroids, Alkylated Compound Inferred Explain 0.70104
12 Malignant neoplasm of breast Disease Known Explain 0.59836
13 Equilenin Compound Inferred Explain 0.54895
14 Equilin Compound Inferred Explain 0.54895
15 Estrone Compound Inferred Explain 0.54748
16 CYP1A1 gene Gene Known Explain 0.47288
17 Prostatic Neoplasms Disease Known Explain 0.40698
18 Guaiacol Compound Inferred Explain 0.38565
19 MAPK3 gene Gene Known Explain 0.35883
20 MAPK1 gene Gene Known Explain 0.31616
21 Gonadal Steroid Hormones Compound Inferred Explain 0.25716
22 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt Compound Inferred Explain 0.17164
23 Phenols Compound Inferred Explain 0.13571
24 Estrogens, Conjugated (USP) Compound Inferred Explain 0.08510
25 Nordihydroguaiaretic Acid Compound Inferred Explain 0.07163
26 17-Ketosteroids Compound Inferred Explain 0.06436
27 Endometrial Stromal Tumors Disease Inferred Explain 0.05814
28 bu-zhong-yi-qi-tang Other Inferred Explain 0.04932
29 STX64 compound Compound Inferred Explain 0.04892
30 STX 213 Compound Inferred Explain 0.04892
31 Estriol Compound Inferred Explain 0.04241
32 Estrenes Compound Inferred Explain 0.04118
33 Carcinoma, Endometrioid Disease Inferred Explain 0.03256
34 Capsaicin Compound Inferred Explain 0.02751
35 Guaifenesin Compound Inferred Explain 0.01914
36 Ethylenethiourea Compound Inferred Explain 0.01345
37 2-methoxyestradiol-3,17-O,O-bis(sulfamate) Compound Inferred Explain 0.01281
38 nitrobenzene Compound Inferred Explain 0.01280
39 2,2',3,4,4',5',6-heptabromodiphenyl ether Compound Inferred Explain 0.01252
40 Phenyl Ethers Compound Inferred Explain 0.01120
41 Deficiency of steroid 17-alpha-monooxygenase Disease Inferred Explain 0.01037
42 Sodium Nitrite Compound Inferred Explain 0.00957
43 Methyl Ethers Compound Inferred Explain 0.00925
44 kahweol Compound Inferred Explain 0.00888
45 cafestol Compound Inferred Explain 0.00888
46 Progesterone Congeners Compound Inferred Explain 0.00848
47 Phytoestrogens Compound Inferred Explain 0.00822
48 Curcumin Compound Inferred Explain 0.00787
49 17alpha,20alpha-Dihydroxycholesterol Compound Inferred Explain 0.00757
50 20alpha-Hydroxycholesterol Compound Inferred Explain 0.00757
51 Uterine Neoplasms Disease Inferred Explain 0.00748
52 7-methylguanine Compound Inferred Explain 0.00731
53 SULT1A3 gene Gene Inferred Explain 0.00709
54 Estradiol Compound Inferred Explain 0.00653
55 Pyrogallol Compound Inferred Explain 0.00634
56 Diiodothyronines Compound Inferred Explain 0.00626
57 Chlorophenols Compound Inferred Explain 0.00613
58 Hydroxyprogesterone Compound Inferred Explain 0.00612
59 JAZF1 gene Gene Inferred Explain 0.00596
60 3,3'-diiodothyronine Compound Inferred Explain 0.00589
61 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine Compound Inferred Explain 0.00589
62 6-hydroxymelatonin Compound Inferred Explain 0.00589
63 5-hydroxyindole Compound Inferred Explain 0.00589
64 harmol Compound Inferred Explain 0.00589
65 Endometrial Stromal Sarcoma Disease Inferred Explain 0.00578
66 3-hydroxybenzo(a)pyrene Compound Inferred Explain 0.00555
67 2-methoxyestradiol Compound Inferred Explain 0.00547
68 N-nitrosodiethanolamine Compound Inferred Explain 0.00528
69 Benserazide Compound Inferred Explain 0.00515
70 2-hydroxyestradiol Compound Inferred Explain 0.00513
71 steroid 17-alpha-hydroxylase-C17-20 lyase activity Function Inferred Explain 0.00507
72 O-methyltransferase, family 3 Domain Inferred Explain 0.00501
73 PANIC DISORDER 1 Disease Inferred Explain 0.00494
74 SK&F-38393 Inferred Explain 0.00493
75 Halogenated Diphenyl Ethers Compound Inferred Explain 0.00476
76 Fenofibrate Compound Inferred Explain 0.00473
77 4-methylcatechol Compound Inferred Explain 0.00460
78 Catechol O-methyltransferase, eukaryotic Domain Inferred Explain 0.00458
79 GSTA1 gene Gene Inferred Explain 0.00455
80 Ethinyl Estradiol Compound Inferred Explain 0.00443
81 Methyldopa Compound Inferred Explain 0.00433
82 15-A(2t)-IsoP Compound Inferred Explain 0.00428
83 pinocembrin Compound Inferred Explain 0.00426
84 UGT1A9 gene Gene Inferred Explain 0.00425
85 Pregnanolone Compound Inferred Explain 0.00424
86 Raynaud Disease Disease Inferred Explain 0.00420
87 Steroid Compound Inferred Explain 0.00414
88 11beta-Hydroxyprogesterone Compound Inferred Explain 0.00414
89 21-Deoxycortisol Compound Inferred Explain 0.00414
90 Sodium, Dietary Compound Inferred Explain 0.00408
91 Gonadal Hormones Compound Inferred Explain 0.00402
92 Hydroxytryptophol Compound Inferred Explain 0.00400
93 CS 045 Compound Inferred Explain 0.00398
94 Testosterone Congeners Compound Inferred Explain 0.00398
95 Androsterone Compound Inferred Explain 0.00395
96 tetrabrominated diphenyl ether 47 Compound Inferred Explain 0.00392
97 4-methylumbelliferone Compound Inferred Explain 0.00392
98 1,2-epoxy-3-(p-nitrophenoxy)propane Compound Inferred Explain 0.00390
99 drospirenone Compound Inferred Explain 0.00387
100 caffeic acid Compound Inferred Explain 0.00384