Asbestosis

Disease • C0003949

Definition

A lung disorder caused by inhalation of asbestos fibers. It results in fibrosis of the lung parenchyma. Signs and symptoms include coughing, shortness of breath and chest pain.

Synonyms

Asbestosis • Asbestoses • PULMONARY ASBESTOSIS • Asbestosis [Disease/Finding]

Linked items?Related concepts, ordered by their global importance in the network.

NOS2 gene    GSTT1 gene    SERPINA1 gene    Chrysotile    Pneumoconiosis   

Related concepts

# Concept name Type Relation Support Score
1 Pneumoconiosis Disease Known Explain 67.26866
2 Chrysotile Compound Known Explain 57.35687
3 SERPINA1 gene Gene Known Explain 17.77111
4 GSTT1 gene Gene Known Explain 11.47679
5 NOS2 gene Gene Known Explain 9.88950
6 Anthracosis Disease Inferred Explain 2.01964
7 Silicosis Disease Inferred Explain 1.78407
8 Caplan Syndrome Disease Inferred Explain 1.09136
9 Anthracosilicosis Disease Inferred Explain 1.00054
10 Berylliosis Other Inferred Explain 0.54210
11 Lung Injury Other Inferred Explain 0.46087
12 Lung Diseases, Interstitial Disease Inferred Explain 0.41477
13 Occupational Diseases Disease Inferred Explain 0.40810
14 Silicotuberculosis Disease Inferred Explain 0.12011
15 Rheumatoid Arthritis Disease Inferred Explain 0.05197
16 Pleural Diseases Disease Inferred Explain 0.03611
17 Pulmonary Fibrosis Disease Inferred Explain 0.03425
18 Lung diseases Disease Inferred Explain 0.03260
19 Neoplasms, Experimental Disease Inferred Explain 0.02736
20 CD59 gene Gene Inferred Explain 0.02485
21 CXCL1 gene Gene Inferred Explain 0.02038
22 CITED1 gene Gene Inferred Explain 0.01921
23 Lung Neoplasms Disease Inferred Explain 0.01741
24 ATF3 gene Gene Inferred Explain 0.01481
25 G6PD gene Gene Inferred Explain 0.01468
26 F3 gene Gene Inferred Explain 0.01382
27 Extrinsic allergic alveolitis Disease Inferred Explain 0.01379
28 Radiation Pneumonitis Other Inferred Explain 0.01239
29 response to methanol Function Inferred Explain 0.01210
30 response to chromate Function Inferred Explain 0.01123
31 HLA-DPB2 gene Gene Inferred Explain 0.01095
32 TERT gene Gene Inferred Explain 0.01089
33 Bird Fancier's Lung Disease Inferred Explain 0.01075
34 Tuberculosis, Pulmonary Disease Inferred Explain 0.01036
35 PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET Disease Inferred Explain 0.00959
36 Prednisone Compound Inferred Explain 0.00916
37 Sleep Disorders, Circadian Rhythm Disease Inferred Explain 0.00894
38 Panniculitis, Nodular Nonsuppurative Disease Inferred Explain 0.00888
39 HRAS gene Gene Inferred Explain 0.00873
40 GSTM1 gene Gene Inferred Explain 0.00855
41 BTNL2 gene Gene Inferred Explain 0.00816
42 Inert Gas Narcosis Other Inferred Explain 0.00773
43 Hydrochloric Acid Compound Inferred Explain 0.00751
44 alpha 1-Antitrypsin Deficiency Disease Inferred Explain 0.00750
45 response to triglyceride Function Inferred Explain 0.00749
46 Vinyl Chloride Compound Inferred Explain 0.00725
47 Persian Gulf Syndrome Disease Inferred Explain 0.00714
48 Bronchiectasis Disease Inferred Explain 0.00690
49 Beryllium Compound Inferred Explain 0.00687
50 GSTM4 gene Gene Inferred Explain 0.00643
51 Laboratory Infection Disease Inferred Explain 0.00640
52 IL8 gene Gene Inferred Explain 0.00628
53 High Pressure Neurological Syndrome Disease Inferred Explain 0.00619
54 BAX gene Gene Inferred Explain 0.00613
55 GSTA4 gene Gene Inferred Explain 0.00590
56 GSTA5 gene Gene Inferred Explain 0.00589
57 Hand-Arm Vibration Syndrome Other Inferred Explain 0.00579
58 DERL3 gene Gene Inferred Explain 0.00570
59 response to lead ion Function Inferred Explain 0.00569
60 Chronic Obstructive Airway Disease Disease Inferred Explain 0.00569
61 GSTM2 gene Gene Inferred Explain 0.00567
62 GSTM5 gene Gene Inferred Explain 0.00562
63 GSTT2 gene Gene Inferred Explain 0.00559
64 GSTA3 gene Gene Inferred Explain 0.00555
65 MAPK8 gene Gene Inferred Explain 0.00549
66 Agricultural Workers' Diseases Disease Inferred Explain 0.00535
67 GSTO2 gene Gene Inferred Explain 0.00525
68 Sarcoidosis, Pulmonary Disease Inferred Explain 0.00520
69 Dermatitis, Occupational Disease Inferred Explain 0.00518
70 Pulmonary Emphysema Disease Inferred Explain 0.00516
71 TP53 gene Gene Inferred Explain 0.00505
72 GSTA2 gene Gene Inferred Explain 0.00498
73 CTRB1 gene Gene Inferred Explain 0.00493
74 Nitric oxide synthase, oxygenase region Domain Inferred Explain 0.00486
75 MMP26 gene Gene Inferred Explain 0.00479
76 GSTM3 gene Gene Inferred Explain 0.00475
77 Toluene 2,4-Diisocyanate Compound Inferred Explain 0.00474
78 GSTP1 gene Gene Inferred Explain 0.00474
79 GSTA1 gene Gene Inferred Explain 0.00472
80 MGST3 gene Gene Inferred Explain 0.00469
81 MAPK14 gene Gene Inferred Explain 0.00465
82 Idiopathic Interstitial Pneumonias Disease Inferred Explain 0.00465
83 KLK13 gene Gene Inferred Explain 0.00461
84 Wegener Granulomatosis Disease Inferred Explain 0.00459
85 Ventilator-Induced Lung Injury Other Inferred Explain 0.00447
86 1,2-epoxy-3-(p-nitrophenoxy)propane Compound Inferred Explain 0.00447
87 Desquamative interstitial pneumonia Disease Inferred Explain 0.00446
88 ADAMTS4 gene Gene Inferred Explain 0.00440
89 Nitric-oxide synthase Domain Inferred Explain 0.00438
90 Histiocytosis, Langerhans-Cell Disease Inferred Explain 0.00437
91 GSTO1 gene Gene Inferred Explain 0.00435
92 MGST2 gene Gene Inferred Explain 0.00419
93 7-methylguanine Compound Inferred Explain 0.00418
94 DERL2 gene Gene Inferred Explain 0.00418
95 Asbestos Compound Inferred Explain 0.00417
96 MYC gene Gene Inferred Explain 0.00415
97 Methyl Chloride Compound Inferred Explain 0.00411
98 Anti-Glomerular Basement Membrane Disease Disease Inferred Explain 0.00411
99 nitric oxide synthase activity Function Inferred Explain 0.00410
100 MGST1 gene Gene Inferred Explain 0.00407